SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)		 4z2q LECTIN
(Athelia
rolfsii) 		4 / 6 VAL A  41
ASP A 133
HIS A 135
TYR A 126
 None
 1.25A 2zs9A-4z2qA:
undetectable		 2zs9A-4z2qA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 4z2q LECTIN
(Athelia
rolfsii) 		4 / 7 LEU A  82
GLU A  86
ASP A  85
SER A  62
 None
 1.20A 3dzgA-4z2qA:
undetectable		 3dzgA-4z2qA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 4z2q LECTIN
(Athelia
rolfsii) 		4 / 7 LEU A  82
GLU A  86
ASP A  85
SER A  62
 None
 1.25A 3dzgB-4z2qA:
undetectable		 3dzgB-4z2qA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4z2q LECTIN
(Athelia
rolfsii) 		4 / 6 GLY A  51
TYR A  95
GLY A  68
ASN A  92
 None
 1.08A 3e9rA-4z2qA:
undetectable		 3e9rA-4z2qA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4z2q LECTIN
(Athelia
rolfsii) 		4 / 6 GLY A  51
TYR A  95
GLY A  68
ASN A  92
 None
 1.00A 3e9rC-4z2qA:
undetectable		 3e9rC-4z2qA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4z2q LECTIN
(Athelia
rolfsii) 		3 / 3 ASP A  77
ARG A 101
ALA A 104
 NAG  A 203 ( 2.6A)
NDG  A 202 ( 3.9A)
NAG  A 203 ( 4.3A)
 0.79A 3mbgC-4z2qA:
undetectable		 3mbgC-4z2qA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4z2q LECTIN
(Athelia
rolfsii) 		3 / 3 GLY A  51
SER A  50
TRP A  75
 None
 0.88A 4e7cD-4z2qA:
undetectable		 4e7cD-4z2qA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4z2q LECTIN
(Athelia
rolfsii) 		5 / 12 GLU A  61
ASN A 116
ILE A  78
ALA A  65
PHE A  67
 None
 1.14A 4u8yB-4z2qA:
undetectable		 4u8yB-4z2qA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4z2q LECTIN
(Athelia
rolfsii) 		4 / 5 ASN A  59
ASP A  14
ASN A  12
ASN A 116
 None
 1.13A 5vooA-4z2qA:
undetectable		 5vooA-4z2qA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4z2q LECTIN
(Athelia
rolfsii) 		4 / 5 ASN A  59
ASP A  14
ASN A  12
ASN A 116
 None
 1.16A 5vooC-4z2qA:
undetectable		 5vooC-4z2qA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4z2q LECTIN
(Athelia
rolfsii) 		4 / 5 ASN A  59
ASP A  14
ASN A  12
ASN A 116
 None
 1.20A 5vooE-4z2qA:
undetectable		 5vooE-4z2qA:
19.33