SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z3l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		8 / 12 PHE A  58
PHE A  62
PHE A  64
THR A  94
ILE A  98
TYR A 120
SER A 136
MET A 139
 None
None
SO4  A 202 (-4.8A)
None
None
None
None
None
 0.81A 1fm4A-4z3lA:
27.6		 1fm4A-4z3lA:
91.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		8 / 12 PHE A  58
PHE A  62
PRO A  63
PHE A  64
THR A  94
TYR A 120
SER A 136
MET A 139
 None
None
None
SO4  A 202 (-4.8A)
None
None
None
None
 0.87A 1fm4A-4z3lA:
27.6		 1fm4A-4z3lA:
91.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		8 / 12 PHE A  58
PHE A  64
THR A  94
ILE A  98
TYR A 120
ALA A 135
SER A 136
MET A 139
 None
SO4  A 202 (-4.8A)
None
None
None
None
None
None
 0.75A 1fm4A-4z3lA:
27.6		 1fm4A-4z3lA:
91.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		8 / 12 PHE A  58
PRO A  63
PHE A  64
THR A  94
TYR A 120
ALA A 135
SER A 136
MET A 139
 None
None
SO4  A 202 (-4.8A)
None
None
None
None
None
 0.85A 1fm4A-4z3lA:
27.6		 1fm4A-4z3lA:
91.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		10 / 12 PHE A  22
ILE A  56
TYR A  81
TYR A  83
VAL A  85
ILE A  98
ASN A 100
ASN A 118
TYR A 120
SER A 136
 None
 0.67A 1fm4A-4z3lA:
27.6		 1fm4A-4z3lA:
91.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		10 / 12 PHE A  22
ILE A  56
TYR A  83
VAL A  85
ILE A  98
ASN A 100
ASN A 118
TYR A 120
SER A 136
LEU A 143
 None
 0.56A 1fm4A-4z3lA:
27.6		 1fm4A-4z3lA:
91.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		9 / 12 PHE A  30
TYR A  83
VAL A  85
ILE A  98
ASN A 100
ASN A 118
TYR A 120
SER A 136
LEU A 143
 None
 1.44A 1fm4A-4z3lA:
27.6		 1fm4A-4z3lA:
91.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 12 ARG A 145
THR A  10
GLY A 111
GLU A 148
ASP A 109
 None
 1.27A 1jdvE-4z3lA:
undetectable
1jdvF-4z3lA:
undetectable		 1jdvE-4z3lA:
22.13
1jdvF-4z3lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		3 / 3 PHE A  30
TYR A  81
TYR A  83
 None
 0.82A 1x70B-4z3lA:
undetectable		 1x70B-4z3lA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 11 ARG A 145
THR A  10
GLY A 111
GLU A 148
ASP A 109
 None
 1.22A 2ac7A-4z3lA:
undetectable
2ac7B-4z3lA:
undetectable		 2ac7A-4z3lA:
22.45
2ac7B-4z3lA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 11 ARG A 145
THR A  10
GLY A 111
GLU A 148
ASP A 109
 None
 1.24A 2ac7A-4z3lA:
undetectable
2ac7B-4z3lA:
undetectable		 2ac7A-4z3lA:
22.45
2ac7B-4z3lA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 11 ARG A 145
THR A  10
GLY A 111
GLU A 148
ASP A 109
 None
 1.24A 3uawA-4z3lA:
undetectable		 3uawA-4z3lA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 12 ALA A 146
LEU A  29
PHE A  30
ILE A 102
LEU A  18
 None
 0.92A 3uvvB-4z3lA:
undetectable		 3uvvB-4z3lA:
19.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		8 / 12 ILE A  23
ASP A  27
LYS A  54
ILE A  56
VAL A  67
ASN A 100
MET A 139
LEU A 143
 None
 0.64A 4a81A-4z3lA:
28.3		 4a81A-4z3lA:
97.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		9 / 12 ILE A  23
ASP A  27
LYS A  54
ILE A  56
VAL A  67
TYR A  81
ASN A 100
ASN A 118
LEU A 143
 None
 0.60A 4a81A-4z3lA:
28.3		 4a81A-4z3lA:
97.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		10 / 12 PHE A  58
PHE A  62
PRO A  63
PHE A  64
LEU A  95
ILE A  98
TYR A 120
ALA A 135
SER A 136
MET A 139
 None
None
None
SO4  A 202 (-4.8A)
None
None
None
None
None
None
 0.85A 4a83A-4z3lA:
27.9		 4a83A-4z3lA:
97.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		8 / 12 PHE A  30
VAL A  67
TYR A  81
TYR A  83
ASN A 100
ASN A 118
SER A 136
LEU A 143
 None
 0.48A 4a83A-4z3lA:
27.9		 4a83A-4z3lA:
97.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		8 / 12 PHE A  30
VAL A  67
TYR A  83
ASN A 100
ASN A 118
SER A 136
MET A 139
LEU A 143
 None
 0.59A 4a83A-4z3lA:
27.9		 4a83A-4z3lA:
97.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 12 PHE A  30
VAL A  85
SER A 136
MET A 139
LEU A 143
 None
 1.04A 4a83A-4z3lA:
27.9		 4a83A-4z3lA:
97.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		10 / 12 ASP A  27
ILE A  56
TYR A  81
TYR A  83
VAL A  85
ILE A  98
ASN A 118
TYR A 120
SER A 136
LEU A 143
 None
 0.57A 4a84A-4z3lA:
27.8		 4a84A-4z3lA:
96.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		10 / 12 ASP A  27
ILE A  56
TYR A  83
VAL A  85
ILE A  98
ASN A 118
TYR A 120
SER A 136
MET A 139
LEU A 143
 None
 0.64A 4a84A-4z3lA:
27.8		 4a84A-4z3lA:
96.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 12 VAL A  41
TYR A  83
ILE A  98
ASN A 118
TYR A 120
 None
 1.23A 4a84A-4z3lA:
27.8		 4a84A-4z3lA:
96.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		9 / 12 PHE A  58
PHE A  62
PRO A  63
PHE A  64
LEU A  95
TYR A 120
VAL A 128
SER A 136
MET A 139
 None
None
None
SO4  A 202 (-4.8A)
None
None
None
None
None
 0.91A 4a84A-4z3lA:
27.8		 4a84A-4z3lA:
96.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		9 / 12 PHE A  58
PRO A  63
PHE A  64
LEU A  95
TYR A 120
VAL A 128
ALA A 135
SER A 136
MET A 139
 None
None
SO4  A 202 (-4.8A)
None
None
None
None
None
None
 0.84A 4a84A-4z3lA:
27.8		 4a84A-4z3lA:
96.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 12 ALA A 146
LEU A  29
PHE A  30
ILE A 102
LEU A  18
 None
 0.81A 6a60D-4z3lA:
undetectable		 6a60D-4z3lA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		3 / 3 SER A 112
SER A  11
ALA A  21
 None
 0.49A 6dwnC-4z3lA:
undetectable		 6dwnC-4z3lA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 4z3l MAJOR POLLEN
ALLERGEN BET V 1-A
(Betula
pendula) 		5 / 9 LEU A 114
SER A 149
LEU A 151
GLU A 148
ILE A  13
 None
 1.13A 6fdyU-4z3lA:
undetectable		 6fdyU-4z3lA:
18.29