SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z45'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_B_CCSB47_0 (GLUTATHIONE S-TRANSFERASE)	4z45	ODORANT-BINDING PROTEIN NRIBOBP3 (Nasonovia ribisnigri)	4 / 7	LEU A 67 GLY A 62 LEU A 51 TYR A 58	None	0.91A	1gtiB-4z45A: undetectable	1gtiB-4z45A: 21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_C_ADNC1503_1 (CLASS B ACID PHOSPHATASE)	4z45	ODORANT-BINDING PROTEIN NRIBOBP3 (Nasonovia ribisnigri)	4 / 8	PHE A 5 TRP A 71 GLY A 66 TYR A 13	None	0.86A	1rmtC-4z45A: undetectable	1rmtC-4z45A: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y0X_X_T44X500_1 (THYROID HORMONE RECEPTOR BETA-1)	4z45	ODORANT-BINDING PROTEIN NRIBOBP3 (Nasonovia ribisnigri)	5 / 12	ILE A 46 MET A 3 MET A 108 LEU A 67 ILE A 82	None	1.28A	1y0xX-4z45A: undetectable	1y0xX-4z45A: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VT7_A_VDXA500_2 (VITAMIN D3 RECEPTOR)	4z45	ODORANT-BINDING PROTEIN NRIBOBP3 (Nasonovia ribisnigri)	4 / 4	LEU A 51 ILE A 10 TYR A 105 TYR A 70	None	1.12A	3vt7A-4z45A: undetectable	3vt7A-4z45A: 19.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTI_B_CCSB47_0","GLUTATHIONE S-TRANSFERASE","4z45","ODORANT-BINDING PROTEIN NRIBOBP3","Nasonovia ribisnigri",4,"LEU A  67;GLY A  62;LEU A  51;TYR A  58","None","0.91A","1gtiB-4z45A:undetectable","1gtiB-4z45A:21.03"],["1RMT_C_ADNC1503_1","CLASS B ACID PHOSPHATASE","4z45","ODORANT-BINDING PROTEIN NRIBOBP3","Nasonovia ribisnigri",4,"PHE A   5;TRP A  71;GLY A  66;TYR A  13","None","0.86A","1rmtC-4z45A:undetectable","1rmtC-4z45A:19.27"],["1Y0X_X_T44X500_1","THYROID HORMONE RECEPTOR BETA-1","4z45","ODORANT-BINDING PROTEIN NRIBOBP3","Nasonovia ribisnigri",5,"ILE A  46;MET A   3;MET A 108;LEU A  67;ILE A  82","None","1.28A","1y0xX-4z45A:undetectable","1y0xX-4z45A:17.19"],["3VT7_A_VDXA500_2","VITAMIN D3 RECEPTOR","4z45","ODORANT-BINDING PROTEIN NRIBOBP3","Nasonovia ribisnigri",4,"LEU A  51;ILE A  10;TYR A 105;TYR A  70","None","1.12A","3vt7A-4z45A:undetectable","3vt7A-4z45A:19.69"]]