SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z61'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 THR A 354
SER A 378
SER A 308
TYR A 282
 None
 0.61A 1ibgL-4z61A:
undetectable		 1ibgL-4z61A:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 GLY A  43
LEU A 112
LEU A  37
ALA A  36
LEU A 115
 None
 1.29A 1jipA-4z61A:
undetectable		 1jipA-4z61A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 8 SER A 143
SER A 142
ASN A 167
GLY A  94
 None
None
None
NAG  A 701 ( 3.7A)
 0.98A 1meiA-4z61A:
undetectable		 1meiA-4z61A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 LEU A 331
ASN A 356
LEU A 298
MET A 294
LEU A 314
 None
 1.40A 1nhzA-4z61A:
undetectable		 1nhzA-4z61A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 11 PHE A 146
LEU A 141
ALA A 107
VAL A 164
LEU A 189
 None
 1.12A 1rlbF-4z61A:
undetectable		 1rlbF-4z61A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.96A 1v55C-4z61A:
undetectable
1v55J-4z61A:
undetectable		 1v55C-4z61A:
16.59
1v55J-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 10 LEU A 181
LEU A 177
ILE A 184
GLU A 166
LEU A 189
 None
 1.20A 1wopA-4z61A:
undetectable		 1wopA-4z61A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 PHE A 411
LEU A 396
LEU A 393
ILE A 395
LEU A 405
 None
 1.01A 1xdkF-4z61A:
undetectable		 1xdkF-4z61A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 5 LEU A 445
LEU A 475
LEU A 453
LEU A 469
 None
 1.06A 1yajD-4z61A:
undetectable		 1yajD-4z61A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 5 ILE A 187
ILE A 222
ILE A 173
LEU A 256
 None
 0.93A 1zgyA-4z61A:
undetectable		 1zgyA-4z61A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 5 ILE A 538
ILE A 573
ILE A 489
LEU A 607
 None
 0.84A 1zgyA-4z61A:
undetectable		 1zgyA-4z61A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.97A 2dysP-4z61A:
undetectable
2dysW-4z61A:
undetectable		 2dysP-4z61A:
16.59
2dysW-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.94A 2eijC-4z61A:
undetectable
2eijJ-4z61A:
undetectable		 2eijC-4z61A:
16.59
2eijJ-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 8 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.92A 2eilC-4z61A:
undetectable
2eilJ-4z61A:
undetectable		 2eilC-4z61A:
16.59
2eilJ-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 6 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 1.00A 2einP-4z61A:
undetectable
2einW-4z61A:
undetectable		 2einP-4z61A:
16.59
2einW-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 2
(Daucus
carota;
Arabidopsis
thaliana) 		5 / 12 SER A 608
PHE A 606
THR C  67
VAL C  66
LEU C  39
 None
 1.40A 2fj1A-4z61A:
undetectable		 2fj1A-4z61A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 ALA A 190
TYR A 165
ASP A 188
TYR A 210
 None
 1.27A 2pncA-4z61A:
undetectable		 2pncA-4z61A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 6 ALA A 190
TYR A 165
ASP A 188
TYR A 210
 None
 1.18A 2pncB-4z61A:
undetectable		 2pncB-4z61A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 LEU A 405
LEU A 430
ILE A 366
PRO A 442
VAL A 441
 None
 1.35A 2pnjB-4z61A:
undetectable		 2pnjB-4z61A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 6 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.99A 2zxwP-4z61A:
undetectable
2zxwW-4z61A:
undetectable		 2zxwP-4z61A:
16.59
2zxwW-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 ILE A 538
ILE A 573
LEU A 499
LEU A 607
 None
 0.81A 3adxA-4z61A:
undetectable		 3adxA-4z61A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 6 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.94A 3ag1C-4z61A:
undetectable
3ag1J-4z61A:
undetectable		 3ag1C-4z61A:
16.59
3ag1J-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.99A 3ag2C-4z61A:
undetectable		 3ag2C-4z61A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 8 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.94A 3ag4C-4z61A:
undetectable
3ag4J-4z61A:
undetectable		 3ag4C-4z61A:
16.59
3ag4J-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 LEU A 229
GLN A 228
PHE A 227
LEU A 211
 None
 0.97A 3asnC-4z61A:
undetectable
3asnJ-4z61A:
undetectable		 3asnC-4z61A:
16.59
3asnJ-4z61A:
5.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		3 / 3 CYH A 399
HIS A 398
PHE A 424
 None
 0.85A 3cr4X-4z61A:
undetectable		 3cr4X-4z61A:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 SER A 380
THR A 408
ILE A 386
ASN A 356
ILE A 355
 None
 1.22A 3ddyA-4z61A:
undetectable		 3ddyA-4z61A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 4z61 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 2
(Arabidopsis
thaliana) 		5 / 12 LEU C 180
LEU C 204
PHE C 198
LEU C 173
ASP C 174
 None
 1.33A 3gwuA-4z61C:
undetectable		 3gwuA-4z61C:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		3 / 3 PRO A 417
PHE A 411
ALA A 392
 None
 0.62A 3itaD-4z61A:
undetectable		 3itaD-4z61A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 GLY A  94
THR A 118
ASP A  49
ILE A  48
LEU A  98
 NAG  A 701 ( 3.7A)
NAG  A 701 (-4.4A)
None
None
None
 1.29A 3iv6C-4z61A:
undetectable		 3iv6C-4z61A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		3 / 3 ARG A 310
ASP A 512
ASP A 332
 NAG  A 704 (-3.4A)
None
None
 0.90A 3jb3A-4z61A:
undetectable		 3jb3A-4z61A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 LEU A 577
ILE A 573
LEU A 588
ASP A 587
PHE A 627
 None
 1.07A 3ko0A-4z61A:
undetectable
3ko0B-4z61A:
undetectable
3ko0C-4z61A:
undetectable
3ko0D-4z61A:
undetectable		 3ko0A-4z61A:
10.84
3ko0B-4z61A:
10.84
3ko0C-4z61A:
10.84
3ko0D-4z61A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 PHE A 627
LEU A 577
ILE A 573
LEU A 588
ASP A 587
 None
 1.03A 3ko0G-4z61A:
undetectable
3ko0H-4z61A:
undetectable
3ko0I-4z61A:
undetectable
3ko0J-4z61A:
undetectable		 3ko0G-4z61A:
10.84
3ko0H-4z61A:
10.84
3ko0I-4z61A:
10.84
3ko0J-4z61A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 11 PHE A 627
LEU A 588
ASP A 587
LEU A 577
ILE A 573
 None
 1.10A 3ko0A-4z61A:
undetectable
3ko0B-4z61A:
undetectable
3ko0I-4z61A:
undetectable
3ko0J-4z61A:
undetectable		 3ko0A-4z61A:
10.84
3ko0B-4z61A:
10.84
3ko0I-4z61A:
10.84
3ko0J-4z61A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 LEU A 577
ILE A 573
LEU A 588
ASP A 587
PHE A 627
 None
 1.01A 3ko0K-4z61A:
undetectable
3ko0L-4z61A:
undetectable
3ko0S-4z61A:
undetectable
3ko0T-4z61A:
undetectable		 3ko0K-4z61A:
10.84
3ko0L-4z61A:
10.84
3ko0S-4z61A:
10.84
3ko0T-4z61A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 LEU A 588
ASP A 587
LEU A 577
ILE A 573
PHE A 627
 None
 1.07A 3ko0K-4z61A:
undetectable
3ko0L-4z61A:
undetectable
3ko0M-4z61A:
undetectable
3ko0N-4z61A:
undetectable		 3ko0K-4z61A:
10.84
3ko0L-4z61A:
10.84
3ko0M-4z61A:
10.84
3ko0N-4z61A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 LEU A 577
ILE A 573
LEU A 588
ASP A 587
PHE A 627
 None
 1.03A 3ko0M-4z61A:
undetectable
3ko0N-4z61A:
undetectable
3ko0O-4z61A:
undetectable
3ko0P-4z61A:
undetectable		 3ko0M-4z61A:
10.84
3ko0N-4z61A:
10.84
3ko0O-4z61A:
10.84
3ko0P-4z61A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 PHE A 627
LEU A 588
ASP A 587
LEU A 577
ILE A 573
 None
 1.05A 3ko0M-4z61A:
undetectable
3ko0N-4z61A:
undetectable
3ko0O-4z61A:
undetectable
3ko0P-4z61A:
undetectable		 3ko0M-4z61A:
10.84
3ko0N-4z61A:
10.84
3ko0O-4z61A:
10.84
3ko0P-4z61A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 LEU A 445
LEU A 430
SER A 457
THR A 408
 None
 1.04A 3lm8A-4z61A:
undetectable
3lm8C-4z61A:
undetectable		 3lm8A-4z61A:
14.33
3lm8C-4z61A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 LEU A 469
LEU A 454
SER A 457
THR A 408
 None
 1.07A 3lm8B-4z61A:
undetectable
3lm8D-4z61A:
undetectable		 3lm8B-4z61A:
14.33
3lm8D-4z61A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 4z61 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 2
(Arabidopsis
thaliana) 		5 / 12 PRO C 161
LEU C 175
ASN C 152
PHE C 132
LEU C 156
 None
 1.50A 3megA-4z61C:
undetectable		 3megA-4z61C:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 2
(Daucus
carota;
Arabidopsis
thaliana) 		5 / 11 LEU C  79
GLU A 584
PHE A 606
LEU C  50
SER C  52
 None
 1.36A 3o94A-4z61C:
undetectable		 3o94A-4z61C:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 2
(Daucus
carota;
Arabidopsis
thaliana) 		5 / 11 LEU C  79
GLU A 584
PHE A 606
LEU C  50
SER C  52
 None
 1.38A 3o94C-4z61C:
undetectable		 3o94C-4z61C:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 2
(Daucus
carota;
Arabidopsis
thaliana) 		5 / 11 LEU C  79
GLU A 584
PHE A 606
LEU C  50
SER C  52
 None
 1.38A 3o94D-4z61C:
undetectable		 3o94D-4z61C:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 7 TRP A 444
PRO A 442
LEU A 454
ASN A 459
 None
 1.03A 3u5jA-4z61A:
undetectable		 3u5jA-4z61A:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 10 ALA A 236
LEU A 226
LEU A 213
ASN A 239
ILE A 198
 None
 1.08A 3wdmB-4z61A:
undetectable		 3wdmB-4z61A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 10 GLY A 212
LEU A 218
LEU A 237
LEU A 211
ILE A 198
 None
 1.10A 3wdmB-4z61A:
undetectable		 3wdmB-4z61A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 9 ALA A 236
LEU A 226
LEU A 213
ASN A 239
ILE A 198
 None
 1.21A 3wdmC-4z61A:
undetectable		 3wdmC-4z61A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 9 GLY A 212
LEU A 218
LEU A 237
LEU A 211
ILE A 198
 None
 1.06A 3wdmC-4z61A:
undetectable		 3wdmC-4z61A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 10 ALA A 214
GLY A 212
LEU A 237
LEU A 211
ILE A 198
 None
 1.18A 3wdmD-4z61A:
undetectable		 3wdmD-4z61A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 10 ALA A 236
LEU A 226
LEU A 213
ASN A 239
ILE A 198
 None
 1.04A 3wdmD-4z61A:
undetectable		 3wdmD-4z61A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 ALA A 127
SER A 129
ILE A 154
SER A 176
PHE A 150
 None
 1.22A 4c49A-4z61A:
undetectable		 4c49A-4z61A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 8 PRO A 199
ILE A 198
LEU A 226
ILE A 202
 None
 0.95A 4dtaB-4z61A:
undetectable		 4dtaB-4z61A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 5 LEU A 451
SER A 446
LEU A 469
LEU A 430
 None
 1.24A 4n09B-4z61A:
undetectable		 4n09B-4z61A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 5 LEU A 451
SER A 446
LEU A 469
LEU A 430
 None
 1.24A 4n09D-4z61A:
undetectable		 4n09D-4z61A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 8 PHE A 146
ILE A 126
LEU A  91
LEU A 112
 None
 0.84A 5hs1A-4z61A:
undetectable		 5hs1A-4z61A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 12 LEU A 407
ILE A 432
LEU A 416
GLY A 439
LEU A 402
 None
 1.11A 5ienA-4z61A:
undetectable		 5ienA-4z61A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		6 / 12 LEU A 416
LEU A 393
LEU A 475
SER A 448
PHE A 424
LEU A 478
 None
 1.29A 5ljeA-4z61A:
undetectable		 5ljeA-4z61A:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 9 ALA A 236
ILE A 202
LEU A 226
ILE A 198
ILE A 173
 None
 0.97A 5nunA-4z61A:
undetectable		 5nunA-4z61A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 10 LEU A 156
ILE A 126
LEU A 102
PHE A  40
LEU A  91
 None
 1.18A 5y7pH-4z61A:
undetectable		 5y7pH-4z61A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		5 / 10 VAL A 106
LEU A 112
LEU A 136
LEU A 117
LEU A  91
 None
 0.91A 6f5uA-4z61A:
undetectable
6f5uB-4z61A:
undetectable		 6f5uA-4z61A:
8.76
6f5uB-4z61A:
8.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 4z61 PHYTOSULFOKINE
RECEPTOR 1
(Daucus
carota) 		4 / 6 LEU A 130
ALA A 107
LEU A 117
SER A 103
 None
 0.87A 6f88B-4z61A:
undetectable		 6f88B-4z61A:
8.96