SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 4z85 2-NITROBENZOATE
NITROREDUCTASE
(Pseudomonas
fluorescens) 		4 / 8 TYR A  44
ILE A  59
LEU A  78
VAL A 156
 None
 0.80A 1fslB-4z85A:
undetectable		 1fslB-4z85A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4z85 2-NITROBENZOATE
NITROREDUCTASE
(Pseudomonas
fluorescens) 		5 / 12 VAL A 129
ILE A  96
ILE A  81
VAL A  92
ILE A  59
 None
 1.06A 1oipA-4z85A:
undetectable		 1oipA-4z85A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 4z85 2-NITROBENZOATE
NITROREDUCTASE
(Pseudomonas
fluorescens) 		5 / 12 VAL A 129
ILE A  96
ILE A  81
VAL A  92
ILE A  59
 None
 1.12A 1r5lA-4z85A:
undetectable		 1r5lA-4z85A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 4z85 2-NITROBENZOATE
NITROREDUCTASE
(Pseudomonas
fluorescens) 		4 / 7 VAL A 129
VAL A 161
TYR A  49
CYH A  39
 None
 1.20A 1t46A-4z85A:
undetectable		 1t46A-4z85A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 4z85 2-NITROBENZOATE
NITROREDUCTASE
(Pseudomonas
fluorescens) 		5 / 11 ARG A  25
ASN A  90
VAL A  92
GLY A 104
ILE A  27
 None
 0.95A 3lzvB-4z85A:
undetectable		 3lzvB-4z85A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 4z85 2-NITROBENZOATE
NITROREDUCTASE
(Pseudomonas
fluorescens) 		4 / 6 ARG A  99
ARG A 166
ASP A 134
ASP A  93
 None
 1.10A 4xqeB-4z85A:
undetectable		 4xqeB-4z85A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 4z85 2-NITROBENZOATE
NITROREDUCTASE
(Pseudomonas
fluorescens) 		4 / 8 ARG A  99
ARG A 166
ASP A 134
ASP A  93
 None
 1.09A 4xqgA-4z85A:
undetectable		 4xqgA-4z85A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 4z85 2-NITROBENZOATE
NITROREDUCTASE
(Pseudomonas
fluorescens) 		4 / 8 ARG A  99
ARG A 166
ASP A 134
ASP A  93
 None
 1.10A 4xqgB-4z85A:
undetectable		 4xqgB-4z85A:
19.16