SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z8i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 4z8i PEPTIDOGLYCAN
RECOGNITION PROTEIN
3
(Branchiostoma
belcheri) 		4 / 4 ASN A  26
SER A 185
ALA A  29
VAL A  30
 None
 1.38A 4x1kC-4z8iA:
undetectable		 4x1kC-4z8iA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4z8i PEPTIDOGLYCAN
RECOGNITION PROTEIN
3
(Branchiostoma
belcheri) 		4 / 5 SER A  95
ARG A 142
GLY A 141
THR A  77
 None
 1.20A 5btiA-4z8iA:
undetectable
5btiB-4z8iA:
undetectable		 5btiA-4z8iA:
18.02
5btiB-4z8iA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 4z8i PEPTIDOGLYCAN
RECOGNITION PROTEIN
3
(Branchiostoma
belcheri) 		3 / 3 ASP A 135
SER A 107
TYR A 139
 None
 0.92A 5glmA-4z8iA:
undetectable		 5glmA-4z8iA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4z8i PEPTIDOGLYCAN
RECOGNITION PROTEIN
3
(Branchiostoma
belcheri) 		5 / 12 LEU A 215
ASP A 204
GLY A 201
ALA A 180
TYR A 225
 None
 1.15A 5kbwB-4z8iA:
undetectable		 5kbwB-4z8iA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4z8i PEPTIDOGLYCAN
RECOGNITION PROTEIN
3
(Branchiostoma
belcheri) 		4 / 5 ASP A 135
ILE A 177
ASN A 112
TYR A 139
 None
 0.91A 6a93B-4z8iA:
undetectable		 6a93B-4z8iA:
17.36