SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z8t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		3 / 3 LEU A 131
SER A 218
ASN A 191
 None
 0.78A 1bx4A-4z8tA:
undetectable		 1bx4A-4z8tA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.87A 1dz9A-4z8tA:
undetectable		 1dz9A-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.92A 1o76B-4z8tA:
undetectable		 1o76B-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.91A 1t85A-4z8tA:
undetectable		 1t85A-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.92A 1t87A-4z8tA:
undetectable		 1t87A-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.87A 1uyuA-4z8tA:
undetectable		 1uyuA-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.89A 1uyuB-4z8tA:
undetectable		 1uyuB-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 1yrcA-4z8tA:
undetectable		 1yrcA-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.89A 1yrdA-4z8tA:
undetectable		 1yrdA-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.91A 2a1oA-4z8tA:
undetectable		 2a1oA-4z8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 6 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.85A 2feuA-4z8tA:
undetectable		 2feuA-4z8tA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 2feuB-4z8tA:
undetectable		 2feuB-4z8tA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 4z8t AVRRXO1-ORF1
AVRRXO1-ORF2
(Xanthomonas
oryzae) 		4 / 6 ASP B  68
ILE B  69
LEU B  60
GLU A 251
 None
 0.70A 2ya7A-4z8tB:
undetectable		 2ya7A-4z8tB:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 4z8t AVRRXO1-ORF1
AVRRXO1-ORF2
(Xanthomonas
oryzae) 		4 / 6 ASP B  68
ILE B  69
LEU B  60
GLU A 251
 None
 0.70A 2ya7B-4z8tB:
undetectable		 2ya7B-4z8tB:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 4z8t AVRRXO1-ORF1
AVRRXO1-ORF2
(Xanthomonas
oryzae) 		4 / 6 ASP B  68
ILE B  69
LEU B  60
GLU A 251
 None
 0.70A 2ya7D-4z8tB:
undetectable		 2ya7D-4z8tB:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 6 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 2z97A-4z8tA:
undetectable		 2z97A-4z8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 6 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.84A 2zuhA-4z8tA:
undetectable		 2zuhA-4z8tA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 6 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.88A 2zuiA-4z8tA:
undetectable		 2zuiA-4z8tA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.87A 2zwtA-4z8tA:
undetectable		 2zwtA-4z8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 2zwuA-4z8tA:
undetectable		 2zwuA-4z8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 3fwfA-4z8tA:
undetectable		 3fwfA-4z8tA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 3fwfB-4z8tA:
undetectable		 3fwfB-4z8tA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.88A 3fwiA-4z8tA:
undetectable		 3fwiA-4z8tA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.87A 3fwjA-4z8tA:
undetectable		 3fwjA-4z8tA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 3l63A-4z8tA:
undetectable		 3l63A-4z8tA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.89A 3wrhA-4z8tA:
undetectable		 3wrhA-4z8tA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.88A 3wrjA-4z8tA:
undetectable		 3wrjA-4z8tA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.88A 3wrlA-4z8tA:
undetectable		 3wrlA-4z8tA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.84A 3wrlE-4z8tA:
undetectable		 3wrlE-4z8tA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.86A 3wrmA-4z8tA:
undetectable		 3wrmA-4z8tA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.88A 3wrmF-4z8tA:
undetectable		 3wrmF-4z8tA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 TYR A 298
VAL A 301
TRP A 410
LEU A 285
 None
 1.07A 4jtrA-4z8tA:
undetectable		 4jtrA-4z8tA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.84A 4l4aA-4z8tA:
undetectable		 4l4aA-4z8tA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.84A 4l4bA-4z8tA:
undetectable		 4l4bA-4z8tA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.79A 4l4cB-4z8tA:
undetectable		 4l4cB-4z8tA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.85A 4l4dA-4z8tA:
undetectable		 4l4dA-4z8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.89A 4l4eA-4z8tA:
undetectable		 4l4eA-4z8tA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 8 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.88A 4l4fA-4z8tA:
undetectable		 4l4fA-4z8tA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.94A 4l4gA-4z8tA:
undetectable		 4l4gA-4z8tA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		5 / 9 ALA A 143
GLU A 144
LEU A 140
GLY A 228
LEU A 229
 None
 1.43A 5wgqA-4z8tA:
undetectable		 5wgqA-4z8tA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		4 / 7 THR A 184
LEU A 142
VAL A 243
VAL A 194
 None
 0.90A 5wk9A-4z8tA:
undetectable		 5wk9A-4z8tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 4z8t AVRRXO1-ORF1
(Xanthomonas
oryzae) 		3 / 3 PRO A 192
SER A 219
SER A 218
 None
 0.63A 6bpyA-4z8tA:
undetectable		 6bpyA-4z8tA:
21.83