SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 4z9a LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Homo
sapiens) 		3 / 3 ARG A  97
VAL A  11
THR A  46
 None
 0.63A 3cyxA-4z9aA:
undetectable		 3cyxA-4z9aA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 4z9a LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Homo
sapiens) 		5 / 9 VAL A   8
LEU A  96
SER A 118
LEU A 115
ILE A 127
 None
 1.37A 4ubsA-4z9aA:
undetectable		 4ubsA-4z9aA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 4z9a LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PROTEIN PHOSPHATASE
(Homo
sapiens) 		3 / 3 ARG A  58
ASP A  56
TYR A 131
 None
None
PMS  A 304 ( 4.6A)
 0.81A 4yo9B-4z9aA:
undetectable		 4yo9B-4z9aA:
17.25