SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		3 / 3 ASP A  11
ARG A   9
ILE A  51
 NAD  A 202 (-3.3A)
NAD  A 202 (-2.6A)
None
 0.77A 1a4gB-4z9dA:
undetectable		 1a4gB-4z9dA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 12 LEU A  36
GLY A  38
LEU A  32
VAL A  95
SER A  40
 None
NAD  A 202 (-3.8A)
None
None
None
 1.10A 1dfoA-4z9dA:
undetectable		 1dfoA-4z9dA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 12 LEU A  36
GLY A  38
LEU A  32
VAL A  95
SER A  40
 None
NAD  A 202 (-3.8A)
None
None
None
 1.10A 1dfoB-4z9dA:
undetectable		 1dfoB-4z9dA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 12 LEU A  36
GLY A  38
LEU A  32
VAL A  95
SER A  40
 None
NAD  A 202 (-3.8A)
None
None
None
 1.10A 1dfoC-4z9dA:
undetectable		 1dfoC-4z9dA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 12 LEU A  36
GLY A  38
LEU A  32
VAL A  95
SER A  40
 None
NAD  A 202 (-3.8A)
None
None
None
 1.10A 1dfoD-4z9dA:
undetectable		 1dfoD-4z9dA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 12 LEU A  36
GLY A  38
LEU A  32
VAL A  95
SER A  40
 None
NAD  A 202 (-3.8A)
None
None
None
 1.07A 1eqbA-4z9dA:
undetectable		 1eqbA-4z9dA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 12 LEU A  36
GLY A  38
LEU A  32
VAL A  95
SER A  40
 None
NAD  A 202 (-3.8A)
None
None
None
 1.06A 1eqbB-4z9dA:
undetectable		 1eqbB-4z9dA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 12 LEU A  36
GLY A  38
LEU A  32
VAL A  95
SER A  40
 None
NAD  A 202 (-3.8A)
None
None
None
 1.07A 1eqbC-4z9dA:
undetectable		 1eqbC-4z9dA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 12 LEU A  36
GLY A  38
LEU A  32
VAL A  95
SER A  40
 None
NAD  A 202 (-3.8A)
None
None
None
 1.06A 1eqbD-4z9dA:
undetectable		 1eqbD-4z9dA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 7 ASN A  85
GLY A 127
ILE A 130
ALA A 121
ILE A  87
 None
 1.11A 1n49A-4z9dA:
undetectable		 1n49A-4z9dA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		5 / 11 THR A  53
ILE A  82
ILE A  87
ALA A  84
VAL A   7
 None
 1.16A 2qhfA-4z9dA:
undetectable		 2qhfA-4z9dA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 5 ALA A  52
GLY A  38
CYH A  41
HIS A  26
 NAD  A 202 (-3.5A)
NAD  A 202 (-3.8A)
NAD  A 202 (-4.1A)
NAD  A 202 (-3.8A)
 1.38A 2yldA-4z9dA:
undetectable		 2yldA-4z9dA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 5 ALA A  52
GLY A  38
CYH A  41
HIS A  26
 NAD  A 202 (-3.5A)
NAD  A 202 (-3.8A)
NAD  A 202 (-4.1A)
NAD  A 202 (-3.8A)
 1.42A 2ylgA-4z9dA:
undetectable		 2ylgA-4z9dA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 7 VAL A  10
ILE A 130
GLY A 127
ARG A  20
 NAD  A 202 (-4.1A)
None
None
None
 0.92A 3bjwH-4z9dA:
undetectable		 3bjwH-4z9dA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 7 GLU A  17
TYR A  78
TYR A  80
PHE A  23
 None
 0.97A 3ku9B-4z9dA:
undetectable		 3ku9B-4z9dA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 6 MET A 113
ILE A  91
SER A  40
SER A  48
 None
 1.29A 3pmzD-4z9dA:
undetectable		 3pmzD-4z9dA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 5 ALA A  52
GLY A  38
CYH A  41
HIS A  26
 NAD  A 202 (-3.5A)
NAD  A 202 (-3.8A)
NAD  A 202 (-4.1A)
NAD  A 202 (-3.8A)
 1.38A 3zwiA-4z9dA:
undetectable		 3zwiA-4z9dA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 4 ALA A  52
GLY A  38
CYH A  41
HIS A  26
 NAD  A 202 (-3.5A)
NAD  A 202 (-3.8A)
NAD  A 202 (-4.1A)
NAD  A 202 (-3.8A)
 1.39A 4cipA-4z9dA:
undetectable		 4cipA-4z9dA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 5 ALA A  52
GLY A  38
CYH A  41
HIS A  26
 NAD  A 202 (-3.5A)
NAD  A 202 (-3.8A)
NAD  A 202 (-4.1A)
NAD  A 202 (-3.8A)
 1.44A 5jliA-4z9dA:
undetectable		 5jliA-4z9dA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 4 ALA A  52
GLY A  38
CYH A  41
HIS A  26
 NAD  A 202 (-3.5A)
NAD  A 202 (-3.8A)
NAD  A 202 (-4.1A)
NAD  A 202 (-3.8A)
 1.40A 5jslA-4z9dA:
undetectable		 5jslA-4z9dA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 4z9d PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA
(Escherichia
coli) 		4 / 5 ALA A  52
GLY A  38
CYH A  41
HIS A  26
 NAD  A 202 (-3.5A)
NAD  A 202 (-3.8A)
NAD  A 202 (-4.1A)
NAD  A 202 (-3.8A)
 1.41A 5jt4A-4z9dA:
undetectable		 5jt4A-4z9dA:
15.08