SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4z9h METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
II
(Escherichia
coli) 		4 / 5 LEU A 137
GLN A 155
THR A 154
THR A 146
 None
 1.34A 2zj0B-4z9hA:
undetectable		 2zj0B-4z9hA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_J_SPMJ202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4z9h METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
II
(Escherichia
coli) 		4 / 7 MET A 116
TYR A 176
GLU A 173
ARG A  47
 None
 1.29A 4r87J-4z9hA:
undetectable
4r87L-4z9hA:
undetectable		 4r87J-4z9hA:
18.05
4r87L-4z9hA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4z9h METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
II
(Escherichia
coli) 		4 / 5 THR A  56
ALA A 100
TYR A 131
HIS A 103
 None
 1.29A 5ecmA-4z9hA:
undetectable		 5ecmA-4z9hA:
15.61