SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 4z9p NUCLEOPROTEIN
(Zaire
ebolavirus) 		4 / 4 HIS A 196
LEU A  77
LEU A 151
LEU A 158
 None
 1.23A 1a4lD-4z9pA:
undetectable		 1a4lD-4z9pA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 4z9p NUCLEOPROTEIN
(Zaire
ebolavirus) 		4 / 6 VAL A 305
GLY A 304
ALA A 297
LEU A 244
 None
 0.80A 1e7bB-4z9pA:
2.3		 1e7bB-4z9pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 4z9p NUCLEOPROTEIN
(Zaire
ebolavirus) 		4 / 8 GLN A 217
LEU A  75
LEU A  99
SER A  93
 None
 1.13A 1hk3A-4z9pA:
3.1		 1hk3A-4z9pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 4z9p NUCLEOPROTEIN
(Zaire
ebolavirus) 		5 / 12 ALA A  82
ASP A 229
ILE A 215
LEU A 158
PRO A 159
 None
 1.00A 1jolB-4z9pA:
undetectable		 1jolB-4z9pA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4z9p NUCLEOPROTEIN
(Zaire
ebolavirus) 		4 / 7 SER A 279
GLN A 315
PHE A 313
ASN A 278
 None
 1.37A 4kcnB-4z9pA:
undetectable		 4kcnB-4z9pA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4z9p NUCLEOPROTEIN
(Zaire
ebolavirus) 		4 / 8 SER A 279
GLN A 315
PHE A 313
ASN A 278
 None
 1.30A 5vunA-4z9pA:
undetectable		 5vunA-4z9pA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4z9p NUCLEOPROTEIN
(Zaire
ebolavirus) 		4 / 8 SER A 279
GLN A 315
PHE A 313
ASN A 278
 None
 1.34A 6auuB-4z9pA:
undetectable		 6auuB-4z9pA:
18.97