SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4z9r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 THR A 269
GLU A 271
GLY A 107
ILE A 337
ALA A 489
None
FMN  A 602 (-3.3A)
FMN  A 602 (-3.2A)
None
None
1.28A 1oltA-4z9rA:
undetectable
1oltA-4z9rA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
4 / 4 VAL A 220
ALA A 265
LEU A 194
PHE A 233
None
1.18A 1q97B-4z9rA:
undetectable
1q97B-4z9rA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
3 / 3 TRP A  21
PHE A  80
TRP A  19
None
1.33A 1r15C-4z9rA:
undetectable
1r15C-4z9rA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
3 / 3 TRP A  21
PHE A  80
TRP A  19
None
1.31A 1r15F-4z9rA:
undetectable
1r15F-4z9rA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
3 / 3 TRP A  21
PHE A  80
TRP A  19
None
1.31A 1r15G-4z9rA:
undetectable
1r15G-4z9rA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
3 / 3 TRP A  21
PHE A  80
TRP A  19
None
1.31A 1r15H-4z9rA:
undetectable
1r15H-4z9rA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
4 / 7 ALA A 511
ARG A 351
ASN A 338
GLU A 343
None
0.97A 1t9wA-4z9rA:
undetectable
1t9wA-4z9rA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
4 / 7 THR A 195
VAL A 175
VAL A 220
VAL A 186
None
1.00A 2qbnA-4z9rA:
undetectable
2qbnA-4z9rA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 TYR A 105
GLY A 107
THR A 269
SER A 336
ALA A 114
None
FMN  A 602 (-3.2A)
None
FMN  A 602 (-2.7A)
None
1.20A 3id6C-4z9rA:
undetectable
3id6C-4z9rA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 10 LEU A 353
ILE A 337
GLY A 275
SER A 468
LEU A 354
None
None
FMN  A 602 ( 4.3A)
None
None
0.88A 3ogpA-4z9rA:
undetectable
3ogpA-4z9rA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 LEU A 286
ALA A 230
SER A 225
LEU A 293
ALA A 265
None
1.34A 3ou7C-4z9rA:
undetectable
3ou7C-4z9rA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 GLY A  85
ALA A 519
ALA A 522
LEU A 322
ASN A 326
None
1.09A 3p5nA-4z9rA:
undetectable
3p5nA-4z9rA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 GLY A  85
ALA A 519
ALA A 522
LEU A 322
ASN A 326
None
1.08A 3p5nB-4z9rA:
undetectable
3p5nB-4z9rA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
4 / 8 ALA A 108
ASN A 160
PHE A 159
ALA A 158
FMN  A 602 (-4.2A)
FMN  A 602 (-3.6A)
None
None
1.08A 3t3sE-4z9rA:
undetectable
3t3sE-4z9rA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
4 / 6 THR A 357
GLY A 488
PRO A 485
GLY A 275
None
None
None
FMN  A 602 ( 4.3A)
0.82A 4fjpA-4z9rA:
undetectable
4fjpA-4z9rA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
4 / 7 THR A 357
GLY A 488
PRO A 485
GLY A 275
None
None
None
FMN  A 602 ( 4.3A)
0.82A 4forA-4z9rA:
undetectable
4forA-4z9rA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 LYS A 294
ALA A 311
GLY A 310
ILE A 315
GLY A 313
None
None
None
None
FMN  A 602 (-3.4A)
0.98A 4obwA-4z9rA:
undetectable
4obwA-4z9rA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 LYS A 294
ALA A 311
GLY A 310
ILE A 315
GLY A 313
None
None
None
None
FMN  A 602 (-3.4A)
1.00A 4obwD-4z9rA:
undetectable
4obwD-4z9rA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.28A 4qvlV-4z9rA:
undetectable
4qvlb-4z9rA:
undetectable
4qvlV-4z9rA:
18.13
4qvlb-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 4qvlH-4z9rA:
undetectable
4qvlN-4z9rA:
undetectable
4qvlH-4z9rA:
18.13
4qvlN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 4qvmV-4z9rA:
undetectable
4qvmb-4z9rA:
undetectable
4qvmV-4z9rA:
18.13
4qvmb-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 4qvmH-4z9rA:
undetectable
4qvmN-4z9rA:
undetectable
4qvmH-4z9rA:
18.13
4qvmN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.28A 4qvpV-4z9rA:
undetectable
4qvpb-4z9rA:
undetectable
4qvpV-4z9rA:
18.13
4qvpb-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 4qvpH-4z9rA:
undetectable
4qvpN-4z9rA:
undetectable
4qvpH-4z9rA:
18.13
4qvpN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.29A 4qvqV-4z9rA:
undetectable
4qvqb-4z9rA:
undetectable
4qvqV-4z9rA:
18.13
4qvqb-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.29A 4qvqH-4z9rA:
undetectable
4qvqN-4z9rA:
undetectable
4qvqH-4z9rA:
18.13
4qvqN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.30A 4qvwV-4z9rA:
undetectable
4qvwb-4z9rA:
undetectable
4qvwV-4z9rA:
18.13
4qvwb-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.30A 4qvwH-4z9rA:
undetectable
4qvwN-4z9rA:
undetectable
4qvwH-4z9rA:
18.13
4qvwN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 4qw0V-4z9rA:
undetectable
4qw0b-4z9rA:
undetectable
4qw0V-4z9rA:
18.13
4qw0b-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 4qw0H-4z9rA:
undetectable
4qw0N-4z9rA:
undetectable
4qw0H-4z9rA:
18.13
4qw0N-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.29A 4qw1V-4z9rA:
undetectable
4qw1b-4z9rA:
undetectable
4qw1V-4z9rA:
18.13
4qw1b-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.29A 4qw1H-4z9rA:
undetectable
4qw1N-4z9rA:
undetectable
4qw1H-4z9rA:
18.13
4qw1N-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.28A 4qw3V-4z9rA:
undetectable
4qw3b-4z9rA:
undetectable
4qw3V-4z9rA:
18.13
4qw3b-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.28A 4qw3H-4z9rA:
undetectable
4qw3N-4z9rA:
undetectable
4qw3H-4z9rA:
18.13
4qw3N-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.30A 4qwuV-4z9rA:
undetectable
4qwub-4z9rA:
undetectable
4qwuV-4z9rA:
18.13
4qwub-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.30A 4qwuH-4z9rA:
undetectable
4qwuN-4z9rA:
undetectable
4qwuH-4z9rA:
18.13
4qwuN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
4 / 4 TYR A 104
THR A 334
GLY A 107
LEU A 118
None
None
FMN  A 602 (-3.2A)
None
1.31A 4w5nA-4z9rA:
undetectable
4w5nA-4z9rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.28A 5bxnV-4z9rA:
undetectable
5bxnb-4z9rA:
undetectable
5bxnV-4z9rA:
18.13
5bxnb-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 5bxnH-4z9rA:
undetectable
5bxnN-4z9rA:
undetectable
5bxnH-4z9rA:
18.13
5bxnN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.28A 5cz7H-4z9rA:
undetectable
5cz7N-4z9rA:
undetectable
5cz7H-4z9rA:
18.13
5cz7N-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.28A 5d0xV-4z9rA:
undetectable
5d0xb-4z9rA:
undetectable
5d0xV-4z9rA:
18.13
5d0xb-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.25A 5d0xH-4z9rA:
undetectable
5d0xN-4z9rA:
undetectable
5d0xH-4z9rA:
18.13
5d0xN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 LEU A 136
GLY A 132
ALA A 114
SER A 115
LEU A 118
None
1.11A 5ikqA-4z9rA:
undetectable
5ikqA-4z9rA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 LEU A 136
GLY A 132
ALA A 114
SER A 115
LEU A 118
None
1.10A 5ikqB-4z9rA:
undetectable
5ikqB-4z9rA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.26A 5l5zV-4z9rA:
undetectable
5l5zb-4z9rA:
undetectable
5l5zV-4z9rA:
18.13
5l5zb-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.26A 5l5zH-4z9rA:
undetectable
5l5zN-4z9rA:
undetectable
5l5zH-4z9rA:
18.13
5l5zN-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 5l66V-4z9rA:
undetectable
5l66b-4z9rA:
undetectable
5l66V-4z9rA:
18.13
5l66b-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 11 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.27A 5l66H-4z9rA:
undetectable
5l66N-4z9rA:
undetectable
5l66H-4z9rA:
18.13
5l66N-4z9rA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.32A 5lf3b-4z9rA:
undetectable
5lf3b-4z9rA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
4z9r OMEGA-3
POLYUNSATURATED
FATTY ACID SYNTHASE
SUBUNIT PFAD

(Shewanella
oneidensis)
5 / 12 THR A 324
THR A 285
GLY A 312
ALA A 270
THR A 269
None
None
FMN  A 602 ( 4.8A)
None
None
1.34A 5lf3N-4z9rA:
undetectable
5lf3N-4z9rA:
17.28