SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4za3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		4 / 6 VAL B 202
ILE B 203
TRP B 172
LEU B 174
 None
 1.13A 1j96A-4za3B:
undetectable		 1j96A-4za3B:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		4 / 8 GLY B 226
PHE B 122
ASP B 178
THR B  94
 None
 0.96A 2aouA-4za3B:
undetectable		 2aouA-4za3B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		4 / 7 GLY B 226
PHE B 122
ASP B 178
THR B  94
 None
 1.01A 2aouB-4za3B:
undetectable		 2aouB-4za3B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		3 / 3 SER B  71
HIS B 101
ASP B  85
 None
 0.69A 2wa2B-4za3B:
undetectable		 2wa2B-4za3B:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		3 / 3 MET B 147
GLU B 150
ASP B 153
 None
 1.10A 3a25A-4za3B:
undetectable		 3a25A-4za3B:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		5 / 12 GLY B 143
ASP B 232
ILE B 243
LEU B 160
ARG B 145
 None
 1.17A 3iv6B-4za3B:
undetectable		 3iv6B-4za3B:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		5 / 12 GLY B 143
ASP B 232
ILE B 243
LEU B 160
ARG B 145
 None
 1.25A 3iv6D-4za3B:
undetectable		 3iv6D-4za3B:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		3 / 3 ALA B 229
VAL B 230
GLN B 255
 None
 0.66A 3of4B-4za3B:
undetectable		 3of4B-4za3B:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		5 / 10 THR B 179
ARG B 181
GLY B 208
ALA B 124
LYS B 125
 None
 1.38A 3pp7B-4za3B:
undetectable		 3pp7B-4za3B:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		3 / 3 ASP B  22
GLY B  25
TYR B  37
 GOL  B 311 (-2.9A)
GOL  B 311 (-3.7A)
GOL  B 311 ( 3.9A)
 0.48A 3w9tC-4za3B:
13.2		 3w9tC-4za3B:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		3 / 3 ASP B  22
GLY B  25
TYR B  37
 GOL  B 311 (-2.9A)
GOL  B 311 (-3.7A)
GOL  B 311 ( 3.9A)
 0.48A 3w9tG-4za3B:
16.4		 3w9tG-4za3B:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		4 / 7 VAL B 103
ILE B 210
SER B  92
THR B  94
 None
 1.06A 5vkqA-4za3B:
undetectable
5vkqD-4za3B:
undetectable		 5vkqA-4za3B:
9.68
5vkqD-4za3B:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		4 / 7 SER B  92
THR B  94
VAL B 103
ILE B 210
 None
 1.06A 5vkqA-4za3B:
undetectable
5vkqB-4za3B:
undetectable		 5vkqA-4za3B:
9.68
5vkqB-4za3B:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		4 / 8 SER B  92
THR B  94
VAL B 103
ILE B 210
 None
 1.03A 5vkqB-4za3B:
undetectable
5vkqC-4za3B:
undetectable		 5vkqB-4za3B:
9.68
5vkqC-4za3B:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4za3 RRNA N-GLYCOSIDASE
(Momordica
charantia) 		4 / 7 SER B  92
THR B  94
VAL B 103
ILE B 210
 None
 1.05A 5vkqC-4za3B:
undetectable
5vkqD-4za3B:
undetectable		 5vkqC-4za3B:
9.68
5vkqD-4za3B:
9.68