SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zal'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYO_A_LNLA1217_1 (LIPOPROTEIN LPPX)	4zal	UBIX (Pseudomonas aeruginosa)	4 / 4	VAL A 111 LEU A 190 ILE A 7 LEU A 9	None	1.01A	2byoA-4zalA: undetectable	2byoA-4zalA: 24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z71_A_PNVA903_1 (PENICILLIN ACYLASE)	4zal	UBIX (Pseudomonas aeruginosa)	5 / 10	THR A 12 PRO A 58 GLU A 121 GLY A 80 GLN A 81	None	1.28A	2z71A-4zalA: undetectable 2z71C-4zalA: undetectable	2z71A-4zalA: 21.13 2z71C-4zalA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M11_B_MXMB606_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4zal	UBIX (Pseudomonas aeruginosa)	5 / 12	ILE A 7 VAL A 99 LEU A 9 LEU A 187 LEU A 190	None	1.04A	4m11B-4zalA: undetectable	4m11B-4zalA: 15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1K_B_LOCB502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	4zal	UBIX (Pseudomonas aeruginosa)	5 / 12	LEU A 157 LEU A 134 ALA A 159 THR A 105 ALA A 124	None	1.13A	4x1kA-4zalA: 3.8 4x1kB-4zalA: 5.7	4x1kA-4zalA: 19.55 4x1kB-4zalA: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_A_SAMA901_0 (MRNA CAPPING ENZYME P5)	4zal	UBIX (Pseudomonas aeruginosa)	5 / 11	GLY A 114 SER A 109 ALA A 124 ASN A 117 ASN A 118	None	1.10A	5x6yA-4zalA: 3.8	5x6yA-4zalA: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_C_SAMC901_0 (MRNA CAPPING ENZYME P5)	4zal	UBIX (Pseudomonas aeruginosa)	5 / 11	GLY A 114 SER A 109 ALA A 124 ASN A 117 ASN A 118	None	1.08A	5x6yC-4zalA: undetectable	5x6yC-4zalA: 13.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BYO_A_LNLA1217_1","LIPOPROTEIN LPPX","4zal","UBIX","Pseudomonas aeruginosa",4,"VAL A 111;LEU A 190;ILE A   7;LEU A   9","None","1.01A","2byoA-4zalA:undetectable","2byoA-4zalA:24.78"],["2Z71_A_PNVA903_1","PENICILLIN ACYLASE;PENICILLIN ACYLASE","4zal","UBIX","Pseudomonas aeruginosa",5,"THR A  12;PRO A  58;GLU A 121;GLY A  80;GLN A  81","None","1.28A","2z71A-4zalA:undetectable;2z71C-4zalA:undetectable","2z71A-4zalA:21.13;2z71C-4zalA:21.13"],["4M11_B_MXMB606_1","PROSTAGLANDIN G\/H SYNTHASE 2","4zal","UBIX","Pseudomonas aeruginosa",5,"ILE A   7;VAL A  99;LEU A   9;LEU A 187;LEU A 190","None","1.04A","4m11B-4zalA:undetectable","4m11B-4zalA:15.06"],["4X1K_B_LOCB502_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","4zal","UBIX","Pseudomonas aeruginosa",5,"LEU A 157;LEU A 134;ALA A 159;THR A 105;ALA A 124","None","1.13A","4x1kA-4zalA:3.8;4x1kB-4zalA:5.7","4x1kA-4zalA:19.55;4x1kB-4zalA:19.63"],["5X6Y_A_SAMA901_0","MRNA CAPPING ENZYME P5","4zal","UBIX","Pseudomonas aeruginosa",5,"GLY A 114;SER A 109;ALA A 124;ASN A 117;ASN A 118","None","1.10A","5x6yA-4zalA:3.8","5x6yA-4zalA:13.23"],["5X6Y_C_SAMC901_0","MRNA CAPPING ENZYME P5","4zal","UBIX","Pseudomonas aeruginosa",5,"GLY A 114;SER A 109;ALA A 124;ASN A 117;ASN A 118","None","1.08A","5x6yC-4zalA:undetectable","5x6yC-4zalA:13.23"]]