SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zb1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 8 HIS A 196
SER A 194
TYR A 177
PHE A  79
 CRQ  A  62 ( 3.7A)
None
None
None
 1.13A 1eqbA-4zb1A:
undetectable
1eqbB-4zb1A:
undetectable		 1eqbA-4zb1A:
19.43
1eqbB-4zb1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 8 TYR A 177
PHE A  79
HIS A 196
SER A 194
 None
None
CRQ  A  62 ( 3.7A)
None
 1.15A 1eqbA-4zb1A:
undetectable
1eqbB-4zb1A:
undetectable		 1eqbA-4zb1A:
19.43
1eqbB-4zb1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 8 HIS A 196
SER A 194
TYR A 177
PHE A  79
 CRQ  A  62 ( 3.7A)
None
None
None
 1.14A 1eqbC-4zb1A:
undetectable
1eqbD-4zb1A:
undetectable		 1eqbC-4zb1A:
19.43
1eqbD-4zb1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 8 TYR A 177
PHE A  79
HIS A 196
SER A 194
 None
None
CRQ  A  62 ( 3.7A)
None
 1.15A 1eqbC-4zb1A:
undetectable
1eqbD-4zb1A:
undetectable		 1eqbC-4zb1A:
19.43
1eqbD-4zb1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 8 GLN A 105
HIS A 196
SER A 194
TYR A  71
 CRQ  A  62 ( 4.0A)
CRQ  A  62 ( 3.7A)
None
None
 1.25A 1nx9A-4zb1A:
undetectable		 1nx9A-4zb1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 8 GLN A 105
HIS A 196
SER A 194
TYR A  71
 CRQ  A  62 ( 4.0A)
CRQ  A  62 ( 3.7A)
None
None
 1.25A 1nx9B-4zb1A:
undetectable		 1nx9B-4zb1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 8 GLN A 105
HIS A 196
SER A 194
TYR A  71
 CRQ  A  62 ( 4.0A)
CRQ  A  62 ( 3.7A)
None
None
 1.24A 1nx9C-4zb1A:
undetectable		 1nx9C-4zb1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 8 GLN A 105
HIS A 196
SER A 194
TYR A  71
 CRQ  A  62 ( 4.0A)
CRQ  A  62 ( 3.7A)
None
None
 1.24A 1nx9D-4zb1A:
undetectable		 1nx9D-4zb1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		5 / 11 GLY A 218
HIS A 192
GLU A 144
HIS A 196
VAL A 217
 None
None
CRQ  A  62 ( 3.5A)
CRQ  A  62 ( 3.7A)
None
 1.13A 1pg2A-4zb1A:
undetectable		 1pg2A-4zb1A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 7 TYR A 177
ARG A 146
GLU A 144
SER A 157
 None
None
CRQ  A  62 ( 3.5A)
CRQ  A  62 ( 2.5A)
 1.27A 2zt7A-4zb1A:
undetectable		 2zt7A-4zb1A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 5 SER A  82
TYR A  78
VAL A  66
ASP A  77
 None
None
CRQ  A  62 ( 4.8A)
None
 1.11A 4eohB-4zb1A:
undetectable		 4eohB-4zb1A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		3 / 3 PRO A 189
MET A 188
TYR A  78
 None
 0.77A 4qa0B-4zb1A:
undetectable		 4qa0B-4zb1A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		3 / 3 PRO A 189
MET A 188
TYR A  78
 None
 0.76A 4qa0A-4zb1A:
undetectable		 4qa0A-4zb1A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		3 / 3 PRO A 189
MET A 188
TYR A  78
 None
 0.80A 4qa2B-4zb1A:
undetectable		 4qa2B-4zb1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		3 / 3 GLY A 129
PRO A 130
ALA A 164
 None
 0.55A 4qn9B-4zb1A:
undetectable		 4qn9B-4zb1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		4 / 6 LYS A  24
GLU A  46
GLY A  47
GLY A  48
 None
 1.05A 5a06D-4zb1A:
undetectable		 5a06D-4zb1A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 4zb1 BLUE CHROMOPROTEIN,
SGBP
(Stichodactyla
gigantea) 		3 / 3 VAL A 152
THR A 176
ARG A 178
 None
 0.76A 5b2sB-4zb1A:
undetectable		 5b2sB-4zb1A:
10.50