SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		5 / 12 ALA A 163
ASP A 164
VAL A 151
ILE A 111
VAL A 155
 None
 0.94A 1k6cB-4zb3A:
undetectable		 1k6cB-4zb3A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.08A 1m8eB-4zb3A:
undetectable		 1m8eB-4zb3A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.09A 1nodB-4zb3A:
undetectable		 1nodB-4zb3A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.05A 1qomA-4zb3A:
undetectable		 1qomA-4zb3A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 VAL A 133
VAL A 121
TRP A 221
 None
 0.95A 1w5uA-4zb3A:
undetectable
1w5uB-4zb3A:
undetectable		 1w5uA-4zb3A:
12.04
1w5uB-4zb3A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.07A 2nodB-4zb3A:
undetectable		 2nodB-4zb3A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.04A 3e68A-4zb3A:
undetectable		 3e68A-4zb3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.05A 3e6tB-4zb3A:
undetectable		 3e6tB-4zb3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.10A 3e7iB-4zb3A:
undetectable		 3e7iB-4zb3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.15A 3nw2A-4zb3A:
undetectable		 3nw2A-4zb3A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		3 / 3 ARG A  74
ILE A  53
TRP A  54
 None
 1.12A 3nw2B-4zb3A:
undetectable		 3nw2B-4zb3A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		5 / 12 ILE A  55
LEU A  38
GLY A  20
GLY A  52
LEU A  42
 None
 0.90A 3uq6A-4zb3A:
undetectable		 3uq6A-4zb3A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		5 / 12 ILE A  55
LEU A  38
GLY A  20
GLY A  52
LEU A  42
 None
 0.87A 3vaqA-4zb3A:
undetectable		 3vaqA-4zb3A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		5 / 12 ILE A  55
LEU A  38
GLY A  20
GLY A  52
LEU A  42
 None
 0.88A 3vasA-4zb3A:
undetectable		 3vasA-4zb3A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4zb3 NUDIX HYDROLASE 7
(Arabidopsis
thaliana) 		5 / 12 VAL A  33
SER A  37
LEU A  38
SER A  41
VAL A  23
 None
 0.96A 3w68A-4zb3A:
undetectable		 3w68A-4zb3A:
20.68