SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		3 / 3 ALA A 166
VAL A 162
TRP A 107
 None
 0.80A 1tkqB-4zb6A:
undetectable		 1tkqB-4zb6A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		3 / 3 GLY A 114
TYR A 118
SER A 113
 None
 0.78A 2xatA-4zb6A:
undetectable		 2xatA-4zb6A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		3 / 3 THR A  98
SER A  93
LYS A 165
 None
 0.96A 3aocC-4zb6A:
undetectable		 3aocC-4zb6A:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		3 / 3 GLN A  80
THR A  79
LEU A 161
 None
 0.69A 3ondA-4zb6A:
undetectable		 3ondA-4zb6A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		3 / 3 GLN A  80
THR A  79
LEU A 161
 None
 0.69A 3ondB-4zb6A:
undetectable		 3ondB-4zb6A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		4 / 6 LEU A 151
SER A 172
PHE A 171
GLU A  28
 None
 1.10A 5b8iA-4zb6A:
undetectable		 5b8iA-4zb6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		4 / 8 ASN A 177
TRP A 160
TRP A 107
PHE A 110
 None
 1.35A 5hqaA-4zb6A:
undetectable		 5hqaA-4zb6A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		4 / 8 TRP A 176
PRO A  60
GLY A  16
PRO A  17
 GDS  A 300 (-4.0A)
GDS  A 300 (-4.5A)
GDS  A 300 (-3.7A)
NA  A 301 ( 4.6A)
 1.03A 5kf8A-4zb6A:
undetectable		 5kf8A-4zb6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		4 / 8 TRP A 176
PRO A  60
GLY A  16
PRO A  17
 GDS  A 300 (-4.0A)
GDS  A 300 (-4.5A)
GDS  A 300 (-3.7A)
NA  A 301 ( 4.6A)
 1.06A 5kgpA-4zb6A:
undetectable		 5kgpA-4zb6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		4 / 8 TRP A 176
PRO A  60
GLY A  16
PRO A  17
 GDS  A 300 (-4.0A)
GDS  A 300 (-4.5A)
GDS  A 300 (-3.7A)
NA  A 301 ( 4.6A)
 1.06A 5kgpB-4zb6A:
undetectable		 5kgpB-4zb6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4zb6 PCURE2P4
(Phanerochaete
chrysosporium) 		4 / 8 LEU A  10
TYR A  33
GLU A  27
THR A  12
 None
 1.07A 6c71B-4zb6A:
undetectable		 6c71B-4zb6A:
17.39