SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		3 / 3 PHE A 173
ASN A 177
PHE A 119
 None
 0.85A 2zbuD-4zbaA:
2.5		 2zbuD-4zbaA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		5 / 12 LEU A  12
LEU A  10
ALA A  17
ALA A  23
HIS A 200
 CL  A 301 (-4.4A)
None
None
None
None
 1.04A 3b0wA-4zbaA:
undetectable		 3b0wA-4zbaA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		5 / 10 ILE A  92
ILE A 171
MET A 166
THR A 208
ILE A 209
 None
 1.23A 5mzrA-4zbaA:
2.1		 5mzrA-4zbaA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		5 / 10 ILE A  92
ILE A 171
MET A 166
THR A 208
ILE A 209
 None
 1.22A 5mzrC-4zbaA:
1.9		 5mzrC-4zbaA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		5 / 9 ILE A  92
ILE A 171
MET A 166
THR A 208
ILE A 209
 None
 1.26A 5mzrD-4zbaA:
2.1		 5mzrD-4zbaA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		3 / 3 LYS A   2
HIS A  65
HIS A   4
 None
 1.39A 5oexA-4zbaA:
undetectable		 5oexA-4zbaA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		3 / 3 LYS A   2
HIS A  65
HIS A   4
 None
 1.36A 5oexB-4zbaA:
undetectable		 5oexB-4zbaA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		3 / 3 LYS A   2
HIS A  65
HIS A   4
 None
 1.34A 5oexC-4zbaA:
undetectable		 5oexC-4zbaA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		3 / 3 LYS A   2
HIS A  65
HIS A   4
 None
 1.32A 5oexD-4zbaA:
undetectable		 5oexD-4zbaA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 4zba PCURE2P8
(Phanerochaete
chrysosporium) 		4 / 7 GLY A 116
PHE A 119
VAL A 123
SER A 175
 None
None
ACT  A 302 (-4.4A)
None
 0.98A 6hu9S-4zbaA:
undetectable
6hu9q-4zbaA:
undetectable		 6hu9S-4zbaA:
16.44
6hu9q-4zbaA:
20.85