SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4zbg ACETYLTRANSFERASE
(Brucella
abortus) 		5 / 12 PHE A 124
PHE A  22
GLY A  79
ALA A  62
GLY A 100
 None
ACO  A 201 (-3.5A)
ACO  A 201 (-3.6A)
None
None
 1.06A 1fe2A-4zbgA:
undetectable		 1fe2A-4zbgA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 4zbg ACETYLTRANSFERASE
(Brucella
abortus) 		5 / 10 LEU A  78
ILE A  97
ARG A  98
ARG A 123
GLY A 119
 ACO  A 201 (-4.7A)
None
None
ACO  A 201 (-3.0A)
None
 1.50A 2qd4B-4zbgA:
undetectable		 2qd4B-4zbgA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4zbg ACETYLTRANSFERASE
(Brucella
abortus) 		5 / 12 ILE A  14
VAL A  50
ILE A  61
ILE A  92
VAL A  36
 None
None
None
ACO  A 201 (-4.3A)
None
 1.24A 3fpjB-4zbgA:
undetectable		 3fpjB-4zbgA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 4zbg ACETYLTRANSFERASE
(Brucella
abortus) 		4 / 8 GLN A  88
PRO A  85
GLN A  56
GLU A  53
 ACO  A 201 (-3.6A)
None
None
None
 0.93A 3oyaA-4zbgA:
undetectable		 3oyaA-4zbgA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 4zbg ACETYLTRANSFERASE
(Brucella
abortus) 		5 / 12 ILE A   3
GLY A  94
ILE A  97
ILE A  14
LEU A  45
 None
ACO  A 201 (-3.6A)
None
None
None
 1.04A 5e72A-4zbgA:
undetectable		 5e72A-4zbgA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 4zbg ACETYLTRANSFERASE
(Brucella
abortus) 		4 / 4 VAL A  17
GLU A  13
GLY A  59
LEU A  84
 None
 1.14A 5g5gC-4zbgA:
1.2		 5g5gC-4zbgA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zbg ACETYLTRANSFERASE
(Brucella
abortus) 		3 / 3 ARG A  40
LEU A  45
PHE A  63
 None
 0.81A 6nknP-4zbgA:
undetectable		 6nknP-4zbgA:
22.58