SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zcf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D1G_A_MTXA171_1 (DIHYDROFOLATE REDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 439 ILE A 178 LEU A 182 ILE A 197 THR A 447	None	1.10A	1d1gA-4zcfA: undetectable	1d1gA-4zcfA: 14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D1G_B_MTXB171_1 (DIHYDROFOLATE REDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 439 ILE A 178 LEU A 182 ILE A 197 THR A 447	None	1.12A	1d1gB-4zcfA: undetectable	1d1gB-4zcfA: 14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G5Y_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ILE A 581 LEU A 623 LEU A 566 ALA A 589 LEU A 578	None	1.10A	1g5yB-4zcfA: undetectable	1g5yB-4zcfA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G60_A_SAMA500_0 (ADENINE-SPECIFIC METHYLTRANSFERASE MBOIIA)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 123 PHE A 441 GLY A 443 SER A 444 THR A 446	None	0.36A	1g60A-4zcfA: 21.2	1g60A-4zcfA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HXB_A_ROCA100_4 (HIV-1 PROTEASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	4 / 4	GLY C 259 ASP C 81 GLY C 253 THR C 268	None	0.96A	1hxbB-4zcfC: undetectable	1hxbB-4zcfC: 8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IBG_H_OBNH1_1 (IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	4 / 6	HIS C 135 LEU C 7 PHE C 136 TYR C 94	None	1.14A	1ibgH-4zcfC: undetectable	1ibgH-4zcfC: 12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NW5_A_SAMA401_0 (MODIFICATION METHYLASE RSRI)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 101 LYS A 418 PHE A 441 GLY A 443 SER A 444	None	0.73A	1nw5A-4zcfA: 21.1	1nw5A-4zcfA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NW5_A_SAMA401_0 (MODIFICATION METHYLASE RSRI)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	PRO A 125 LYS A 418 PHE A 441 GLY A 443 SER A 444	None	0.59A	1nw5A-4zcfA: 21.1	1nw5A-4zcfA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P93_D_DEXD4999_2 (GLUCOCORTICOID RECEPTOR)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	LEU A 640 TRP A 549 LEU A 580 GLN A 620	None	1.49A	1p93D-4zcfA: undetectable	1p93D-4zcfA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QHY_A_CLMA888_0 (CHLORAMPHENICOL PHOSPHOTRANSFERASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 6	PRO A 514 MET A 513 ALA A 79 GLU A 540	None	1.24A	1qhyA-4zcfA: 2.4	1qhyA-4zcfA: 13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RA3_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 439 ILE A 178 LEU A 182 ILE A 197 THR A 447	None	1.08A	1ra3A-4zcfA: undetectable	1ra3A-4zcfA: 14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YC2_E_NCAE507_0 (NAD-DEPENDENT DEACETYLASE 2)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	4 / 7	ILE C 80 PHE C 222 LEU C 101 ASN C 78	None	0.91A	1yc2E-4zcfC: undetectable	1yc2E-4zcfC: 14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_A_SAMA301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	3 / 3	LYS A 266 ASP A 432 ASN A 261	None	1.12A	2bm9A-4zcfA: 2.4	2bm9A-4zcfA: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DRC_B_MTXB161_1 (DIHYDROFOLATE REDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 439 ILE A 178 LEU A 182 ILE A 197 THR A 447	None	1.08A	2drcB-4zcfA: undetectable	2drcB-4zcfA: 14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FT9_A_CHDA130_0 (FATTY ACID-BINDING PROTEIN 2, LIVER)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	PHE A 29 ILE A 44 ILE A 43 PHE A 25 LEU A 21	None	1.12A	2ft9A-4zcfA: undetectable	2ft9A-4zcfA: 11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6G_A_VD3A701_2 (CYTOCHROME P450 2R1)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	3 / 3	MET A 109 VAL A 117 GLU A 187	None	0.79A	3c6gA-4zcfA: undetectable	3c6gA-4zcfA: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DRC_B_MTXB361_1 (DIHYDROFOLATE REDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 439 ILE A 178 LEU A 182 ILE A 197 THR A 447	None	1.07A	3drcB-4zcfA: undetectable	3drcB-4zcfA: 14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EEY_D_SAMD300_0 (PUTATIVE RRNA METHYLASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 264 ILE A 314 GLY A 273 LEU A 303 PRO A 302	None	1.20A	3eeyD-4zcfA: 3.6	3eeyD-4zcfA: 14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_A_H3PA552_1 (GLUTAMATE DEHYDROGENASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 6	ILE A 374 MET A 356 ILE A 333 HIS A 335	None	1.15A	3eteA-4zcfA: undetectable 3eteE-4zcfA: undetectable	3eteA-4zcfA: 21.50 3eteE-4zcfA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_C_H3PC554_1 (GLUTAMATE DEHYDROGENASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	ILE A 374 MET A 356 ILE A 333 HIS A 335	None	1.16A	3eteB-4zcfA: undetectable 3eteC-4zcfA: 1.9	3eteB-4zcfA: 21.50 3eteC-4zcfA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_F_H3PF552_1 (GLUTAMATE DEHYDROGENASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 7	MET A 356 ILE A 333 HIS A 335 ILE A 374	None	1.14A	3eteD-4zcfA: undetectable 3eteF-4zcfA: undetectable	3eteD-4zcfA: 21.50 3eteF-4zcfA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWX_A_EPAA1_2 (PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA)))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	THR A 446 THR A 447 THR A 450 LEU A 422 ILE A 197	None	0.90A	3gwxA-4zcfA: undetectable	3gwxA-4zcfA: 19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_A_1N1A2000_1 (P38A)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	5 / 12	ASP C 226 ILE C 225 VAL C 149 ILE C 167 ILE C 241	AMP C1001 (-3.1A) None None None None	1.23A	3ohtA-4zcfC: undetectable 3ohtB-4zcfC: undetectable	3ohtA-4zcfC: 17.50 3ohtB-4zcfC: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QEL_D_QELD2_1 (NMDA GLUTAMATE RECEPTOR SUBUNIT GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	TYR A 179 THR A 176 PHE A 177 LEU A 207	None	0.97A	3qelC-4zcfA: 3.8	3qelC-4zcfA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RUN_A_CCSA165_0 (LYSOZYME)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	3 / 3	ASN A 228 ALA A 229 LYS A 227	None	0.90A	3runA-4zcfA: undetectable	3runA-4zcfA: 14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3S_B_9PLB1_1 (CYTOCHROME P450 2A13)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 6	PHE A 407 PHE A 414 ALA A 417 THR A 446	None	1.15A	3t3sB-4zcfA: undetectable	3t3sB-4zcfA: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1476_0 (MJ0495-LIKE PROTEIN)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	ILE A 427 ALA A 430 MET A 119 ARG A 190	None	1.35A	4ac9B-4zcfA: undetectable 4ac9C-4zcfA: 2.7	4ac9B-4zcfA: 23.12 4ac9C-4zcfA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EQL_A_SALA602_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	4 / 7	LEU C 267 TYR C 265 THR C 93 GLY C 89	None None None AMP C1001 (-3.4A)	0.95A	4eqlA-4zcfC: undetectable	4eqlA-4zcfC: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EQL_B_SALB602_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	4 / 7	LEU C 267 TYR C 265 THR C 93 GLY C 89	None None None AMP C1001 (-3.4A)	0.95A	4eqlB-4zcfC: undetectable	4eqlB-4zcfC: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G5J_A_0WMA1103_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	ASN A 111 ARG A 643 HIS A 108 LEU A 78	None	1.46A	4g5jA-4zcfA: undetectable	4g5jA-4zcfA: 19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IFX_A_ACTA405_0 (THIAMINE BIOSYNTHESIS LIPOPROTEIN APBE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	LEU A 175 LYS A 63 TRP A 60 ASN A 59	None	1.19A	4ifxA-4zcfA: 0.0	4ifxA-4zcfA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L39_A_SALA602_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	4 / 6	LEU C 267 TYR C 265 THR C 93 GLY C 89	None None None AMP C1001 (-3.4A)	0.97A	4l39A-4zcfC: undetectable	4l39A-4zcfC: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L39_B_SALB601_1 (4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	4 / 7	LEU C 267 TYR C 265 THR C 93 GLY C 89	None None None AMP C1001 (-3.4A)	0.95A	4l39B-4zcfC: 1.6	4l39B-4zcfC: 20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM4_B_8PRB603_2 (TRANSPORTER)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	3 / 3	SER A 617 MET A 621 ASP C 750	None	0.92A	4mm4B-4zcfA: undetectable	4mm4B-4zcfA: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P68_A_MTXA201_1 (DIHYDROFOLATE REDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	5 / 11	ILE C 223 PHE C 244 LYS C 243 ILE C 167 ILE C 111	None	1.39A	4p68A-4zcfC: undetectable	4p68A-4zcfC: 10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P6X_G_HCYG900_2 (GLUCOCORTICOID RECEPTOR)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	3 / 3	LEU A 545 MET A 513 TYR A 552	None	0.67A	4p6xG-4zcfA: undetectable	4p6xG-4zcfA: 17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_B_SAMB301_1 (PUTATIVE METHYLTRANSFERASE BUD23)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	GLN A 468 SER A 444 ASP A 123 ASP A 200	None	1.31A	4qtuB-4zcfA: 2.4	4qtuB-4zcfA: 16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_1 (PUTATIVE METHYLTRANSFERASE BUD23)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	GLN A 468 SER A 444 ASP A 123 ASP A 200	None	1.27A	4qtuD-4zcfA: 5.0	4qtuD-4zcfA: 16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTS_A_SAMA301_0 (DNA ADENINE METHYLASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	PHE A 441 GLY A 443 ASP A 123 PRO A 125 TYR A 126	None	0.92A	4rtsA-4zcfA: 2.3	4rtsA-4zcfA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDT_A_ACTA408_0 (FAD:PROTEIN FMN TRANSFERASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	LEU A 175 LYS A 63 TRP A 60 ASN A 59	None	1.18A	4xdtA-4zcfA: 0.0	4xdtA-4zcfA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_B_SORB1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 7	PHE A 204 ASP A 223 ILE A 245 TYR A 247	None	0.87A	5a06B-4zcfA: undetectable	5a06B-4zcfA: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ERG_B_SAMB401_1 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE CATALYTIC SUBUNIT TRM61)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 7	GLY A 443 SER A 444 ASP A 101 ASP A 439	None	0.75A	5ergB-4zcfA: 5.2	5ergB-4zcfA: 21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H4D_A_BBIA403_1 (NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	4 / 6	PHE A 141 ARG A 139 PHE C 176 GLU A 104	None	1.42A	5h4dA-4zcfA: undetectable	5h4dA-4zcfA: 17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_A_SAMA301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 101 ASP A 123 PHE A 441 GLY A 443 THR A 446	None	0.65A	5hfjA-4zcfA: 18.8	5hfjA-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_A_SAMA301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 123 PRO A 125 PHE A 441 GLY A 443 THR A 446	None	0.61A	5hfjA-4zcfA: 18.8	5hfjA-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_B_SAMB301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 123 PRO A 125 PHE A 441 GLY A 443 THR A 446	None	0.72A	5hfjB-4zcfA: 18.2	5hfjB-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_C_SAMC301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 101 LYS A 418 PHE A 441 GLY A 443 THR A 446	None	0.82A	5hfjC-4zcfA: 19.3	5hfjC-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_C_SAMC301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	PRO A 125 LYS A 418 PHE A 441 GLY A 443 THR A 446	None	0.66A	5hfjC-4zcfA: 19.3	5hfjC-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_D_SAMD301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	ASP A 101 PHE A 441 GLY A 443 SER A 444 THR A 446	None	0.72A	5hfjD-4zcfA: 18.2	5hfjD-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_D_SAMD301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	PRO A 125 PHE A 441 GLY A 443 SER A 444 THR A 446	None	0.67A	5hfjD-4zcfA: 18.2	5hfjD-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_E_SAME301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	7 / 12	ASP A 101 ASP A 123 LYS A 418 PHE A 441 GLY A 443 SER A 444 THR A 446	None	0.79A	5hfjE-4zcfA: 18.7	5hfjE-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_G_SAMG301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	6 / 12	ASP A 123 PRO A 125 LYS A 418 PHE A 441 GLY A 443 THR A 446	None	0.75A	5hfjG-4zcfA: 18.6	5hfjG-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_H_SAMH301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	7 / 12	ASP A 101 ASP A 123 PRO A 125 LYS A 418 PHE A 441 GLY A 443 THR A 446	None	0.87A	5hfjH-4zcfA: 18.7	5hfjH-4zcfA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGR_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	3 / 3	VAL A 437 TYR A 462 GLN A 463	None	0.74A	5qgrA-4zcfA: undetectable	5qgrA-4zcfA: 15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGT_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	3 / 3	VAL A 437 TYR A 462 GLN A 463	None	0.75A	5qgtA-4zcfA: undetectable	5qgtA-4zcfA: 15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UH6_C_RFPC1201_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	5 / 12	LEU C 101 ASP C 139 SER C 104 ILE C 782 HIS C 135	None	1.43A	5uh6C-4zcfC: undetectable	5uh6C-4zcfC: 21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UHG_C_RFPC1201_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	5 / 12	LEU C 101 ASP C 139 SER C 104 ILE C 782 HIS C 135	None	1.36A	5uhgC-4zcfC: undetectable	5uhgC-4zcfC: 21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB308_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	3 / 3	LEU A 377 ILE A 365 TYR A 331	None	0.67A	5uunB-4zcfA: undetectable	5uunB-4zcfA: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_B_C2FB3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	5 / 12	GLY C 122 LYS C 120 VAL C 540 LEU C 489 SER C 129	AMP C1001 (-3.7A) None None None None	1.16A	5vopB-4zcfC: undetectable	5vopB-4zcfC: 15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_C_CHDC304_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	4 / 5	LEU A 495 PHE A 507 LEU A 97 PHE A 488	None	1.02A	5x19C-4zcfA: undetectable 5x19J-4zcfA: undetectable	5x19C-4zcfA: 17.05 5x19J-4zcfA: 6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DIF_B_TPVB201_0 (HIV-1 PROTEASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT (Escherichia coli)	5 / 12	LEU A 224 ASP A 123 ILE A 427 VAL A 246 ILE A 244	None	1.17A	6difA-4zcfA: undetectable	6difA-4zcfA: 8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNA_A_ACTA307_0 (THIOREDOXIN REDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	3 / 3	ARG C 505 LYS C 527 TYR C 556	None	1.33A	6gnaA-4zcfC: undetectable	6gnaA-4zcfC: 16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNB_A_ACTA307_0 (THIOREDOXIN REDUCTASE)	4zcf	RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT (Escherichia coli)	3 / 3	ARG C 505 LYS C 527 TYR C 556	None	1.33A	6gnbA-4zcfC: undetectable	6gnbA-4zcfC: 16.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D1G_A_MTXA171_1","DIHYDROFOLATE REDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 439;ILE A 178;LEU A 182;ILE A 197;THR A 447","None","1.10A","1d1gA-4zcfA:undetectable","1d1gA-4zcfA:14.68"],["1D1G_B_MTXB171_1","DIHYDROFOLATE REDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 439;ILE A 178;LEU A 182;ILE A 197;THR A 447","None","1.12A","1d1gB-4zcfA:undetectable","1d1gB-4zcfA:14.68"],["1G5Y_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ILE A 581;LEU A 623;LEU A 566;ALA A 589;LEU A 578","None","1.10A","1g5yB-4zcfA:undetectable","1g5yB-4zcfA:17.39"],["1G60_A_SAMA500_0","ADENINE-SPECIFIC METHYLTRANSFERASE MBOIIA","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 123;PHE A 441;GLY A 443;SER A 444;THR A 446","None","0.36A","1g60A-4zcfA:21.2","1g60A-4zcfA:19.17"],["1HXB_A_ROCA100_4","HIV-1 PROTEASE;HIV-1 PROTEASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",4,"GLY C 259;ASP C  81;GLY C 253;THR C 268","None","0.96A","1hxbB-4zcfC:undetectable","1hxbB-4zcfC:8.13"],["1IBG_H_OBNH1_1","IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",4,"HIS C 135;LEU C   7;PHE C 136;TYR C  94","None","1.14A","1ibgH-4zcfC:undetectable","1ibgH-4zcfC:12.65"],["1NW5_A_SAMA401_0","MODIFICATION METHYLASE RSRI","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 101;LYS A 418;PHE A 441;GLY A 443;SER A 444","None","0.73A","1nw5A-4zcfA:21.1","1nw5A-4zcfA:21.13"],["1NW5_A_SAMA401_0","MODIFICATION METHYLASE RSRI","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"PRO A 125;LYS A 418;PHE A 441;GLY A 443;SER A 444","None","0.59A","1nw5A-4zcfA:21.1","1nw5A-4zcfA:21.13"],["1P93_D_DEXD4999_2","GLUCOCORTICOID RECEPTOR","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"LEU A 640;TRP A 549;LEU A 580;GLN A 620","None","1.49A","1p93D-4zcfA:undetectable","1p93D-4zcfA:19.75"],["1QHY_A_CLMA888_0","CHLORAMPHENICOL PHOSPHOTRANSFERASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"PRO A 514;MET A 513;ALA A  79;GLU A 540","None","1.24A","1qhyA-4zcfA:2.4","1qhyA-4zcfA:13.71"],["1RA3_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 439;ILE A 178;LEU A 182;ILE A 197;THR A 447","None","1.08A","1ra3A-4zcfA:undetectable","1ra3A-4zcfA:14.60"],["1YC2_E_NCAE507_0","NAD-DEPENDENT DEACETYLASE 2","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",4,"ILE C  80;PHE C 222;LEU C 101;ASN C  78","None","0.91A","1yc2E-4zcfC:undetectable","1yc2E-4zcfC:14.75"],["2BM9_A_SAMA301_1","CEPHALOSPORIN HYDROXYLASE CMCI","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",3,"LYS A 266;ASP A 432;ASN A 261","None","1.12A","2bm9A-4zcfA:2.4","2bm9A-4zcfA:18.01"],["2DRC_B_MTXB161_1","DIHYDROFOLATE REDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 439;ILE A 178;LEU A 182;ILE A 197;THR A 447","None","1.08A","2drcB-4zcfA:undetectable","2drcB-4zcfA:14.60"],["2FT9_A_CHDA130_0","FATTY ACID-BINDING PROTEIN 2, LIVER","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"PHE A  29;ILE A  44;ILE A  43;PHE A  25;LEU A  21","None","1.12A","2ft9A-4zcfA:undetectable","2ft9A-4zcfA:11.61"],["3C6G_A_VD3A701_2","CYTOCHROME P450 2R1","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",3,"MET A 109;VAL A 117;GLU A 187","None","0.79A","3c6gA-4zcfA:undetectable","3c6gA-4zcfA:22.80"],["3DRC_B_MTXB361_1","DIHYDROFOLATE REDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 439;ILE A 178;LEU A 182;ILE A 197;THR A 447","None","1.07A","3drcB-4zcfA:undetectable","3drcB-4zcfA:14.60"],["3EEY_D_SAMD300_0","PUTATIVE RRNA METHYLASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 264;ILE A 314;GLY A 273;LEU A 303;PRO A 302","None","1.20A","3eeyD-4zcfA:3.6","3eeyD-4zcfA:14.60"],["3ETE_A_H3PA552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"ILE A 374;MET A 356;ILE A 333;HIS A 335","None","1.15A","3eteA-4zcfA:undetectable;3eteE-4zcfA:undetectable","3eteA-4zcfA:21.50;3eteE-4zcfA:21.50"],["3ETE_C_H3PC554_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"ILE A 374;MET A 356;ILE A 333;HIS A 335","None","1.16A","3eteB-4zcfA:undetectable;3eteC-4zcfA:1.9","3eteB-4zcfA:21.50;3eteC-4zcfA:21.50"],["3ETE_F_H3PF552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"MET A 356;ILE A 333;HIS A 335;ILE A 374","None","1.14A","3eteD-4zcfA:undetectable;3eteF-4zcfA:undetectable","3eteD-4zcfA:21.50;3eteF-4zcfA:21.50"],["3GWX_A_EPAA1_2","PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA))","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"THR A 446;THR A 447;THR A 450;LEU A 422;ILE A 197","None","0.90A","3gwxA-4zcfA:undetectable","3gwxA-4zcfA:19.54"],["3OHT_A_1N1A2000_1","P38A;P38A","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",5,"ASP C 226;ILE C 225;VAL C 149;ILE C 167;ILE C 241","AMP C1001 (-3.1A);None;None;None;None","1.23A","3ohtA-4zcfC:undetectable;3ohtB-4zcfC:undetectable","3ohtA-4zcfC:17.50;3ohtB-4zcfC:17.50"],["3QEL_D_QELD2_1","NMDA GLUTAMATE RECEPTOR SUBUNIT;GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"TYR A 179;THR A 176;PHE A 177;LEU A 207","None","0.97A","3qelC-4zcfA:3.8","3qelC-4zcfA:21.25"],["3RUN_A_CCSA165_0","LYSOZYME","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",3,"ASN A 228;ALA A 229;LYS A 227","None","0.90A","3runA-4zcfA:undetectable","3runA-4zcfA:14.05"],["3T3S_B_9PLB1_1","CYTOCHROME P450 2A13","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"PHE A 407;PHE A 414;ALA A 417;THR A 446","None","1.15A","3t3sB-4zcfA:undetectable","3t3sB-4zcfA:21.07"],["4AC9_C_DXCC1476_0","MJ0495-LIKE PROTEIN","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"ILE A 427;ALA A 430;MET A 119;ARG A 190","None","1.35A","4ac9B-4zcfA:undetectable;4ac9C-4zcfA:2.7","4ac9B-4zcfA:23.12;4ac9C-4zcfA:23.12"],["4EQL_A_SALA602_1","4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",4,"LEU C 267;TYR C 265;THR C  93;GLY C  89","None;None;None;AMP C1001 (-3.4A)","0.95A","4eqlA-4zcfC:undetectable","4eqlA-4zcfC:20.35"],["4EQL_B_SALB602_1","4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",4,"LEU C 267;TYR C 265;THR C  93;GLY C  89","None;None;None;AMP C1001 (-3.4A)","0.95A","4eqlB-4zcfC:undetectable","4eqlB-4zcfC:20.35"],["4G5J_A_0WMA1103_1","EPIDERMAL GROWTH FACTOR RECEPTOR","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"ASN A 111;ARG A 643;HIS A 108;LEU A  78","None","1.46A","4g5jA-4zcfA:undetectable","4g5jA-4zcfA:19.97"],["4IFX_A_ACTA405_0","THIAMINE BIOSYNTHESIS LIPOPROTEIN APBE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"LEU A 175;LYS A  63;TRP A  60;ASN A  59","None","1.19A","4ifxA-4zcfA:0.0","4ifxA-4zcfA:19.01"],["4L39_A_SALA602_1","4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",4,"LEU C 267;TYR C 265;THR C  93;GLY C  89","None;None;None;AMP C1001 (-3.4A)","0.97A","4l39A-4zcfC:undetectable","4l39A-4zcfC:20.35"],["4L39_B_SALB601_1","4-SUBSTITUTED BENZOATES-GLUTAMATE LIGASE GH3.12","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",4,"LEU C 267;TYR C 265;THR C  93;GLY C  89","None;None;None;AMP C1001 (-3.4A)","0.95A","4l39B-4zcfC:1.6","4l39B-4zcfC:20.35"],["4MM4_B_8PRB603_2","TRANSPORTER","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT;RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",3,"SER A 617;MET A 621;ASP C 750","None","0.92A","4mm4B-4zcfA:undetectable","4mm4B-4zcfA:22.30"],["4P68_A_MTXA201_1","DIHYDROFOLATE REDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",5,"ILE C 223;PHE C 244;LYS C 243;ILE C 167;ILE C 111","None","1.39A","4p68A-4zcfC:undetectable","4p68A-4zcfC:10.42"],["4P6X_G_HCYG900_2","GLUCOCORTICOID RECEPTOR","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",3,"LEU A 545;MET A 513;TYR A 552","None","0.67A","4p6xG-4zcfA:undetectable","4p6xG-4zcfA:17.88"],["4QTU_B_SAMB301_1","PUTATIVE METHYLTRANSFERASE BUD23","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"GLN A 468;SER A 444;ASP A 123;ASP A 200","None","1.31A","4qtuB-4zcfA:2.4","4qtuB-4zcfA:16.23"],["4QTU_D_SAMD301_1","PUTATIVE METHYLTRANSFERASE BUD23","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"GLN A 468;SER A 444;ASP A 123;ASP A 200","None","1.27A","4qtuD-4zcfA:5.0","4qtuD-4zcfA:16.23"],["4RTS_A_SAMA301_0","DNA ADENINE METHYLASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"PHE A 441;GLY A 443;ASP A 123;PRO A 125;TYR A 126","None","0.92A","4rtsA-4zcfA:2.3","4rtsA-4zcfA:19.37"],["4XDT_A_ACTA408_0","FAD:PROTEIN FMN TRANSFERASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"LEU A 175;LYS A  63;TRP A  60;ASN A  59","None","1.18A","4xdtA-4zcfA:0.0","4xdtA-4zcfA:19.01"],["5A06_B_SORB1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"PHE A 204;ASP A 223;ILE A 245;TYR A 247","None","0.87A","5a06B-4zcfA:undetectable","5a06B-4zcfA:20.47"],["5ERG_B_SAMB401_1","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRM61","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"GLY A 443;SER A 444;ASP A 101;ASP A 439","None","0.75A","5ergB-4zcfA:5.2","5ergB-4zcfA:21.98"],["5H4D_A_BBIA403_1","NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT;RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",4,"PHE A 141;ARG A 139;PHE C 176;GLU A 104","None","1.42A","5h4dA-4zcfA:undetectable","5h4dA-4zcfA:17.49"],["5HFJ_A_SAMA301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 101;ASP A 123;PHE A 441;GLY A 443;THR A 446","None","0.65A","5hfjA-4zcfA:18.8","5hfjA-4zcfA:17.36"],["5HFJ_A_SAMA301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 123;PRO A 125;PHE A 441;GLY A 443;THR A 446","None","0.61A","5hfjA-4zcfA:18.8","5hfjA-4zcfA:17.36"],["5HFJ_B_SAMB301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 123;PRO A 125;PHE A 441;GLY A 443;THR A 446","None","0.72A","5hfjB-4zcfA:18.2","5hfjB-4zcfA:17.36"],["5HFJ_C_SAMC301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 101;LYS A 418;PHE A 441;GLY A 443;THR A 446","None","0.82A","5hfjC-4zcfA:19.3","5hfjC-4zcfA:17.36"],["5HFJ_C_SAMC301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"PRO A 125;LYS A 418;PHE A 441;GLY A 443;THR A 446","None","0.66A","5hfjC-4zcfA:19.3","5hfjC-4zcfA:17.36"],["5HFJ_D_SAMD301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"ASP A 101;PHE A 441;GLY A 443;SER A 444;THR A 446","None","0.72A","5hfjD-4zcfA:18.2","5hfjD-4zcfA:17.36"],["5HFJ_D_SAMD301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"PRO A 125;PHE A 441;GLY A 443;SER A 444;THR A 446","None","0.67A","5hfjD-4zcfA:18.2","5hfjD-4zcfA:17.36"],["5HFJ_E_SAME301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",7,"ASP A 101;ASP A 123;LYS A 418;PHE A 441;GLY A 443;SER A 444;THR A 446","None","0.79A","5hfjE-4zcfA:18.7","5hfjE-4zcfA:17.36"],["5HFJ_G_SAMG301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",6,"ASP A 123;PRO A 125;LYS A 418;PHE A 441;GLY A 443;THR A 446","None","0.75A","5hfjG-4zcfA:18.6","5hfjG-4zcfA:17.36"],["5HFJ_H_SAMH301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",7,"ASP A 101;ASP A 123;PRO A 125;LYS A 418;PHE A 441;GLY A 443;THR A 446","None","0.87A","5hfjH-4zcfA:18.7","5hfjH-4zcfA:17.36"],["5QGR_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",3,"VAL A 437;TYR A 462;GLN A 463","None","0.74A","5qgrA-4zcfA:undetectable","5qgrA-4zcfA:15.90"],["5QGT_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",3,"VAL A 437;TYR A 462;GLN A 463","None","0.75A","5qgtA-4zcfA:undetectable","5qgtA-4zcfA:15.90"],["5UH6_C_RFPC1201_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",5,"LEU C 101;ASP C 139;SER C 104;ILE C 782;HIS C 135","None","1.43A","5uh6C-4zcfC:undetectable","5uh6C-4zcfC:21.87"],["5UHG_C_RFPC1201_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",5,"LEU C 101;ASP C 139;SER C 104;ILE C 782;HIS C 135","None","1.36A","5uhgC-4zcfC:undetectable","5uhgC-4zcfC:21.87"],["5UUN_B_ACTB308_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",3,"LEU A 377;ILE A 365;TYR A 331","None","0.67A","5uunB-4zcfA:undetectable","5uunB-4zcfA:17.03"],["5VOP_B_C2FB3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",5,"GLY C 122;LYS C 120;VAL C 540;LEU C 489;SER C 129","AMP C1001 (-3.7A);None;None;None;None","1.16A","5vopB-4zcfC:undetectable","5vopB-4zcfC:15.19"],["5X19_C_CHDC304_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",4,"LEU A 495;PHE A 507;LEU A  97;PHE A 488","None","1.02A","5x19C-4zcfA:undetectable;5x19J-4zcfA:undetectable","5x19C-4zcfA:17.05;5x19J-4zcfA:6.69"],["6DIF_B_TPVB201_0","HIV-1 PROTEASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, MODIFICATION SUBUNIT","Escherichia coli",5,"LEU A 224;ASP A 123;ILE A 427;VAL A 246;ILE A 244","None","1.17A","6difA-4zcfA:undetectable","6difA-4zcfA:8.72"],["6GNA_A_ACTA307_0","THIOREDOXIN REDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",3,"ARG C 505;LYS C 527;TYR C 556","None","1.33A","6gnaA-4zcfC:undetectable","6gnaA-4zcfC:16.32"],["6GNB_A_ACTA307_0","THIOREDOXIN REDUCTASE","4zcf","RESTRICTION ENDONUCLEASE ECOP15I, RESTRICTION SUBUNIT","Escherichia coli",3,"ARG C 505;LYS C 527;TYR C 556","None","1.33A","6gnbA-4zcfC:undetectable","6gnbA-4zcfC:16.32"]]