SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zdh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 4zdh BETA CHAIN OF JKF6
T-CELL
RECEPTOR,PROTEIN
TRBV28
(Homo
sapiens) 		4 / 6 LYS B  13
LEU B  11
GLU B  17
VAL B 119
 None
 1.17A 1sn5A-4zdhB:
undetectable		 1sn5A-4zdhB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 4zdh BETA CHAIN OF JKF6
T-CELL
RECEPTOR,PROTEIN
TRBV28
(Homo
sapiens) 		3 / 3 ARG B  14
SER B  65
TYR B  64
 None
 0.75A 1x70A-4zdhB:
undetectable		 1x70A-4zdhB:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 4zdh BETA CHAIN OF JKF6
T-CELL
RECEPTOR,PROTEIN
TRBV28
(Homo
sapiens) 		4 / 6 HIS B 153
ARG B 109
GLN B   6
PRO B 106
 None
 1.33A 2qqtA-4zdhB:
undetectable		 2qqtA-4zdhB:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4zdh BETA CHAIN OF JKF6
T-CELL
RECEPTOR,PROTEIN
TRBV28
(Homo
sapiens) 		3 / 3 SER B   8
GLU B  17
ASP B 115
 None
 0.74A 2zulA-4zdhB:
undetectable		 2zulA-4zdhB:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4zdh BETA CHAIN OF JKF6
T-CELL
RECEPTOR,PROTEIN
TRBV28
(Homo
sapiens) 		3 / 3 SER B   8
GLU B  17
ASP B 115
 None
 0.76A 3dmhA-4zdhB:
undetectable		 3dmhA-4zdhB:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 4zdh BETA CHAIN OF JKF6
T-CELL
RECEPTOR,PROTEIN
TRBV28
(Homo
sapiens) 		4 / 6 HIS B 153
ARG B 109
GLN B   6
PRO B 106
 None
 1.32A 3gclA-4zdhB:
undetectable		 3gclA-4zdhB:
16.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 4zdh BETA CHAIN OF JKF6
T-CELL
RECEPTOR,PROTEIN
TRBV28
(Homo
sapiens) 		4 / 5 TYR B  47
LYS B  57
GLY B  63
SER B  65
 None
 0.54A 5jhdJ-4zdhB:
29.8		 5jhdJ-4zdhB:
77.14