SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zdn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CQE_A_FLPA1650_1 (PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1))	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	VAL A 797 LEU A 560 LEU A 799 TYR A 564 GLY A 911	None	0.94A	1cqeA-4zdnA: undetectable	1cqeA-4zdnA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CQE_B_FLPB2650_1 (PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1))	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	VAL A 797 LEU A 560 LEU A 799 TYR A 564 GLY A 911	None	0.93A	1cqeB-4zdnA: undetectable	1cqeB-4zdnA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FE2_A_LAXA700_2 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	LEU A 731 GLY A 752 ALA A 751 GLY A 559 LEU A 557	None	1.04A	1fe2A-4zdnA: undetectable	1fe2A-4zdnA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IEP_B_STIB202_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 7	VAL A 754 VAL A 675 ARG A 645 LEU A 716	None	0.90A	1iepB-4zdnA: undetectable	1iepB-4zdnA: 17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IGX_A_EPAA700_1 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	LEU A 731 GLY A 752 ALA A 751 GLY A 559 LEU A 557	None	1.08A	1igxA-4zdnA: undetectable	1igxA-4zdnA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHO_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	THR A 864 GLY A 869 GLY A 782 PHE A 781 GLY A 785	None	1.15A	1jhoA-4zdnA: undetectable	1jhoA-4zdnA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHR_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	THR A 864 GLY A 869 GLY A 782 PHE A 781 GLY A 785	None	1.15A	1jhrA-4zdnA: undetectable	1jhrA-4zdnA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHY_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	THR A 864 GLY A 869 GLY A 782 PHE A 781 GLY A 785	None	1.17A	1jhyA-4zdnA: undetectable	1jhyA-4zdnA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L4N_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	THR A 864 GLY A 869 GLY A 782 PHE A 781 GLY A 785	None	1.19A	1l4nA-4zdnA: undetectable	1l4nA-4zdnA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5K_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	THR A 864 GLY A 869 GLY A 782 PHE A 781 GLY A 785	None	1.14A	1l5kA-4zdnA: undetectable	1l5kA-4zdnA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5L_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	THR A 864 GLY A 869 GLY A 782 PHE A 781 GLY A 785	None	1.16A	1l5lA-4zdnA: undetectable	1l5lA-4zdnA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5M_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	THR A 864 GLY A 869 GLY A 782 PHE A 781 GLY A 785	None	1.16A	1l5mA-4zdnA: undetectable	1l5mA-4zdnA: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_A_SAMA2201_1 (PROTEIN (METHIONINE REPRESSOR))	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 4	HIS A 823 ALA A 974 PHE A 969 GLY A 824	None	1.39A	1mj2B-4zdnA: undetectable	1mj2B-4zdnA: 9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_C_SAMC1200_1 (PROTEIN (METHIONINE REPRESSOR))	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 4	HIS A 823 ALA A 974 PHE A 969 GLY A 824	None	1.39A	1mj2D-4zdnA: undetectable	1mj2D-4zdnA: 9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_A_SAMA199_1 (METHIONINE REPRESSOR)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 4	HIS A 823 ALA A 974 PHE A 969 GLY A 824	None	1.39A	1mjoB-4zdnA: undetectable	1mjoB-4zdnA: 9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_B_SAMB200_0 (METHIONINE REPRESSOR)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 4	HIS A 823 ALA A 974 PHE A 969 GLY A 824	None	1.39A	1mjoA-4zdnA: undetectable	1mjoA-4zdnA: 9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_D_SAMD200_1 (METHIONINE REPRESSOR)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 4	HIS A 823 ALA A 974 PHE A 969 GLY A 824	None	1.39A	1mjoD-4zdnA: undetectable	1mjoD-4zdnA: 9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_A_DVAA6_0 (GRAMICIDIN A)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	3 / 3	ALA A1125 VAL A1127 TRP A1130	None	0.76A	1nt5A-4zdnA: undetectable	1nt5A-4zdnA: 4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_B_DVAB6_0 (GRAMICIDIN A)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	3 / 3	ALA A1125 VAL A1127 TRP A1130	None	0.76A	1nt5B-4zdnA: undetectable	1nt5B-4zdnA: 4.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RLB_F_REAF177_1 (RETINOL BINDING PROTEIN)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 11	LEU A1031 ALA A1053 VAL A1034 LEU A1166 LEU A1019	None	1.13A	1rlbF-4zdnA: undetectable	1rlbF-4zdnA: 13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WG8_B_SAMB3141_0 (PREDICTED S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	GLY A 678 GLY A 753 GLY A 795 ASP A 724 SER A 729	None	1.16A	1wg8B-4zdnA: undetectable	1wg8B-4zdnA: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1O_A_CAMA1422_0 (CYTOCHROME P450-CAM)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 8	TYR A 564 THR A 913 GLY A 752 VAL A 654	None	0.91A	2a1oA-4zdnA: undetectable	2a1oA-4zdnA: 21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_A_1FLA2003_1 (SERUM ALBUMIN)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	LEU A 741 LEU A 748 HIS A 669 LEU A 798 ALA A 805	None	1.16A	2bxeA-4zdnA: undetectable	2bxeA-4zdnA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2003_1 (SERUM ALBUMIN)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 10	LEU A 741 LEU A 748 HIS A 669 LEU A 798 ALA A 805	None	1.13A	2bxeB-4zdnA: undetectable	2bxeB-4zdnA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXP_A_P1ZA3001_1 (SERUM ALBUMIN)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	LEU A 912 LEU A 557 LEU A 799 ALA A 749 ALA A 796	None	1.15A	2bxpA-4zdnA: undetectable	2bxpA-4zdnA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CC8_A_RBFA1067_1 (VNG1446H)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	3 / 3	PHE A1142 VAL A1127 TRP A1130	None	0.57A	2cc8A-4zdnA: 2.7	2cc8A-4zdnA: 7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CCB_A_RBFA1067_1 (VNG1446H)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	3 / 3	PHE A1142 VAL A1127 TRP A1130	None	0.59A	2ccbA-4zdnA: undetectable	2ccbA-4zdnA: 7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	PHE A 647 LEU A 706 ALA A 623 PHE A 622 VAL A 794	None	0.99A	2g70A-4zdnA: undetectable	2g70A-4zdnA: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_B_SAMB2002_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	PHE A 647 LEU A 706 ALA A 623 PHE A 622 VAL A 794	None	0.95A	2g70B-4zdnA: undetectable	2g70B-4zdnA: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	PHE A 647 LEU A 706 ALA A 623 PHE A 622 VAL A 794	None	0.90A	2g72A-4zdnA: undetectable	2g72A-4zdnA: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HRC_A_CHDA702_0 (FERROCHELATASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 7	ARG A1015 LEU A1019 PRO A1161 VAL A1164	None	1.11A	2hrcA-4zdnA: undetectable	2hrcA-4zdnA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_B_CHDB501_0 (FERROCHELATASE, MITOCHONDRIAL)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 11	LEU A1067 PHE A1066 LEU A1063 LEU A1166 VAL A1034	None	1.32A	2po5B-4zdnA: 3.4	2po5B-4zdnA: 17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_A_KLNA1500_1 (CYTOCHROME P450 3A4)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 11	ILE A 909 ALA A 906 ARG A 624 GLU A 649 LEU A 619	None	1.41A	2v0mA-4zdnA: undetectable	2v0mA-4zdnA: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VX9_A_RBFA1064_1 (DODECIN)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	3 / 3	PHE A1142 VAL A1127 TRP A1130	None	0.59A	2vx9A-4zdnA: undetectable	2vx9A-4zdnA: 7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AOC_C_ERYC3402_0 (ACRIFLAVINE RESISTANCE PROTEIN B)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	SER A 895 PHE A 939 ILE A 874 LEU A 789 ASP A 775	None	1.17A	3aocC-4zdnA: undetectable	3aocC-4zdnA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_C_ACTC800_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	3 / 3	ASP A 639 ARG A 635 ALA A 638	None	0.79A	3mbgC-4zdnA: 2.2	3mbgC-4zdnA: 10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_D_SAMD300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	LEU A 928 GLU A 923 ALA A 925 GLY A 580 LEU A 577	None	1.41A	3ou6D-4zdnA: undetectable	3ou6D-4zdnA: 15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXW_D_017D200_1 (HIV-1 PROTEASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 10	ALA A 567 ASP A 566 ILE A 900 GLY A 793 VAL A 794	None	1.01A	3oxwC-4zdnA: undetectable	3oxwC-4zdnA: 10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGH_B_FLPB701_1 (CYCLOOXYGENASE-2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 11	VAL A 797 LEU A 560 LEU A 799 TYR A 564 GLY A 911	None	0.95A	3pghB-4zdnA: undetectable	3pghB-4zdnA: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGH_D_FLPD701_1 (CYCLOOXYGENASE-2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	VAL A 797 LEU A 560 LEU A 799 TYR A 564 GLY A 911	None	0.95A	3pghD-4zdnA: undetectable	3pghD-4zdnA: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R0L_D_ACTD127_0 (PHOSPHOLIPASE A2 CB)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 5	PHE A 676 GLY A 718 CYH A 746 HIS A 740	None	1.21A	3r0lD-4zdnA: undetectable	3r0lD-4zdnA: 9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RR3_C_FLRC700_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	VAL A 797 LEU A 560 LEU A 799 TYR A 564 GLY A 911	None	0.97A	3rr3C-4zdnA: undetectable	3rr3C-4zdnA: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RR3_D_FLRD700_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	VAL A 797 LEU A 560 LEU A 799 TYR A 564 GLY A 911	None	0.98A	3rr3D-4zdnA: undetectable	3rr3D-4zdnA: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UBO_B_ADNB353_1 (ADENOSINE KINASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	ASN A 899 ILE A 900 GLY A 791 GLY A 901 LEU A 577	None	1.09A	3uboB-4zdnA: undetectable	3uboB-4zdnA: 21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ7_B_SAMB302_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 5	SER A 898 ASP A 870 ASP A 936 ILE A 937	None	1.19A	3uj7B-4zdnA: undetectable	3uj7B-4zdnA: 15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JQ1_B_NPSB401_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 8	HIS A 977 VAL A 817 ILE A 816 LEU A 731	None	0.88A	4jq1B-4zdnA: undetectable	4jq1B-4zdnA: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KQI_A_NIOA403_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	THR A 864 GLY A 869 GLY A 782 PHE A 781 GLY A 785	None	1.16A	4kqiA-4zdnA: undetectable	4kqiA-4zdnA: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LS7_A_1X9A504_1 (3-OXOACYL-[ACYL-CARR IER-PROTEIN] SYNTHASE 2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	CYH A 727 HIS A 862 THR A 864 HIS A 902 GLY A 970	None	0.61A	4ls7A-4zdnA: 47.6	4ls7A-4zdnA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LS7_B_1X9B503_1 (3-OXOACYL-[ACYL-CARR IER-PROTEIN] SYNTHASE 2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	CYH A 727 HIS A 862 THR A 864 HIS A 902 GLY A 970	None	0.60A	4ls7A-4zdnA: 47.6 4ls7B-4zdnA: 47.4	4ls7A-4zdnA: 20.09 4ls7B-4zdnA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BS8_G_MFXG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 7	ARG A1106 GLY A1105 THR A1009 GLU A1047	None None CL A1202 ( 4.4A) None	0.91A	5bs8A-4zdnA: undetectable 5bs8C-4zdnA: undetectable 5bs8D-4zdnA: undetectable	5bs8A-4zdnA: 22.69 5bs8C-4zdnA: 22.69 5bs8D-4zdnA: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTA_G_MFXG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 7	ARG A1106 GLY A1105 THR A1009 GLU A1047	None None CL A1202 ( 4.4A) None	0.91A	5btaA-4zdnA: undetectable 5btaC-4zdnA: undetectable 5btaD-4zdnA: undetectable	5btaA-4zdnA: 22.27 5btaC-4zdnA: 22.27 5btaD-4zdnA: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTA_H_MFXH101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCAC GTAA)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 6	ARG A1106 GLY A1105 THR A1009 GLU A1047	None None CL A1202 ( 4.4A) None	0.92A	5btaA-4zdnA: undetectable 5btaB-4zdnA: undetectable 5btaC-4zdnA: undetectable	5btaA-4zdnA: 22.27 5btaB-4zdnA: 17.34 5btaC-4zdnA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTC_G_CPFG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 6	ARG A1106 GLY A1105 THR A1009 GLU A1047	None None CL A1202 ( 4.4A) None	0.99A	5btcA-4zdnA: undetectable 5btcC-4zdnA: undetectable 5btcD-4zdnA: undetectable	5btcA-4zdnA: 22.27 5btcC-4zdnA: 22.27 5btcD-4zdnA: 17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTC_G_CPFG102_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 6	ARG A1106 GLY A1105 THR A1009 GLU A1047	None None CL A1202 ( 4.4A) None	1.01A	5btcA-4zdnA: undetectable 5btcB-4zdnA: undetectable 5btcC-4zdnA: undetectable	5btcA-4zdnA: 22.27 5btcB-4zdnA: 17.34 5btcC-4zdnA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTF_F_GFNF101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 7	ARG A1106 GLY A1105 THR A1009 GLU A1047	None None CL A1202 ( 4.4A) None	0.96A	5btfA-4zdnA: undetectable 5btfB-4zdnA: undetectable 5btfC-4zdnA: undetectable	5btfA-4zdnA: 22.27 5btfB-4zdnA: 17.34 5btfC-4zdnA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTG_E_LFXE101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCAC GTAA)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 6	ARG A1106 GLY A1105 THR A1009 GLU A1047	None None CL A1202 ( 4.4A) None	0.96A	5btgA-4zdnA: undetectable 5btgB-4zdnA: undetectable 5btgC-4zdnA: undetectable	5btgA-4zdnA: 22.69 5btgB-4zdnA: 17.34 5btgC-4zdnA: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5C0O_H_SAMH301_1 (TRNA (ADENINE(58)-N(1))-M ETHYLTRANSFERASE TRMI)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 5	THR A 864 GLY A 787 HIS A 929 ASP A 870	None	1.26A	5c0oH-4zdnA: undetectable	5c0oH-4zdnA: 17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ENT_C_MIYC901_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB,MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 9	SER A 762 GLU A 792 ASN A 755 ILE A 679 ALA A 677	None	1.40A	5entC-4zdnA: 0.9	5entC-4zdnA: 23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHZ_C_REAC602_1 (ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 10	ILE A 900 GLY A 791 PHE A 573 LEU A 619 LEU A 756	None	1.02A	5fhzC-4zdnA: undetectable	5fhzC-4zdnA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGI_A_ZITA402_2 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 6	HIS A 921 GLU A 571 ALA A 579 TYR A 564	None	0.96A	5igiA-4zdnA: undetectable	5igiA-4zdnA: 19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKR_B_ID8B602_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	VAL A 797 LEU A 560 LEU A 799 TYR A 564 GLY A 911	None	0.89A	5ikrB-4zdnA: undetectable	5ikrB-4zdnA: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JNC_D_ACTD305_0 (CARBONIC ANHYDRASE 4)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 5	PRO A 634 ALA A 637 ALA A 627 ILE A 632	None	0.79A	5jncD-4zdnA: undetectable	5jncD-4zdnA: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JVZ_B_FLPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	VAL A 797 LEU A 560 LEU A 799 TYR A 564 GLY A 911	None	0.95A	5jvzB-4zdnA: undetectable	5jvzB-4zdnA: 18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M0O_A_EPAA502_1 (TERMINAL OLEFIN-FORMING FATTY ACID DECARBOXYLASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 10	ILE A 632 PHE A 630 PRO A 634 ALA A 637 PHE A 625	None EPE A1201 (-4.8A) None None None	1.24A	5m0oA-4zdnA: undetectable	5m0oA-4zdnA: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 4	GLN A 947 THR A 927 GLU A 860 LEU A 877	None	1.08A	5m66A-4zdnA: undetectable	5m66A-4zdnA: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N1T_W_CUW201_0 (COPC)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	3 / 3	HIS A 929 ASP A 775 HIS A 777	None	0.87A	5n1tW-4zdnA: undetectable	5n1tW-4zdnA: 13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWU_A_ACAA18_1 (WTFP-TAG,GP41)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	ALA A 849 GLY A 818 SER A 819 GLU A 860 LEU A 912	None	1.21A	5nwuA-4zdnA: undetectable	5nwuA-4zdnA: 6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA410_0 (UNCHARACTERIZED PROTEIN KDOO)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 4	GLY A 776 LEU A 789 VAL A 584 GLU A 582	None	1.48A	5yw0A-4zdnA: undetectable	5yw0A-4zdnA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 12	ILE A 859 PHE A 881 ASP A 884 ILE A 979 LEU A 846	None	1.09A	6dwnD-4zdnA: undetectable	6dwnD-4zdnA: 9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GTQ_B_ACTB207_0 (DUF1778 DOMAIN-CONTAINING PROTEIN N-ACETYLTRANSFERASE)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	4 / 6	LEU A1166 THR A1037 GLY A 659 ARG A1042	None	1.35A	6gtqB-4zdnA: undetectable 6gtqD-4zdnA: undetectable	6gtqB-4zdnA: 17.05 6gtqD-4zdnA: 5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HQB_A_PQNA2001_0 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1 PHOTOSYSTEM I REACTION CENTER SUBUNIT IX)	4zdn	AT-LESS POLYKETIDE SYNTHASE (Streptomyces platensis)	5 / 10	SER A 780 GLY A 865 ALA A 773 LEU A 789 GLY A 901	None	1.35A	6hqbA-4zdnA: undetectable 6hqbJ-4zdnA: undetectable	6hqbA-4zdnA: 8.90 6hqbJ-4zdnA: 5.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CQE_A_FLPA1650_1","PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1)","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"VAL A 797;LEU A 560;LEU A 799;TYR A 564;GLY A 911","None","0.94A","1cqeA-4zdnA:undetectable","1cqeA-4zdnA:21.73"],["1CQE_B_FLPB2650_1","PROTEIN (PROSTAGLANDIN H2 SYNTHASE-1)","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"VAL A 797;LEU A 560;LEU A 799;TYR A 564;GLY A 911","None","0.93A","1cqeB-4zdnA:undetectable","1cqeB-4zdnA:21.73"],["1FE2_A_LAXA700_2","PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"LEU A 731;GLY A 752;ALA A 751;GLY A 559;LEU A 557","None","1.04A","1fe2A-4zdnA:undetectable","1fe2A-4zdnA:21.56"],["1IEP_B_STIB202_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"VAL A 754;VAL A 675;ARG A 645;LEU A 716","None","0.90A","1iepB-4zdnA:undetectable","1iepB-4zdnA:17.64"],["1IGX_A_EPAA700_1","PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"LEU A 731;GLY A 752;ALA A 751;GLY A 559;LEU A 557","None","1.08A","1igxA-4zdnA:undetectable","1igxA-4zdnA:21.56"],["1JHO_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"THR A 864;GLY A 869;GLY A 782;PHE A 781;GLY A 785","None","1.15A","1jhoA-4zdnA:undetectable","1jhoA-4zdnA:20.78"],["1JHR_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"THR A 864;GLY A 869;GLY A 782;PHE A 781;GLY A 785","None","1.15A","1jhrA-4zdnA:undetectable","1jhrA-4zdnA:20.78"],["1JHY_A_NIOA991_1","NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"THR A 864;GLY A 869;GLY A 782;PHE A 781;GLY A 785","None","1.17A","1jhyA-4zdnA:undetectable","1jhyA-4zdnA:20.78"],["1L4N_A_NIOA991_1","NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"THR A 864;GLY A 869;GLY A 782;PHE A 781;GLY A 785","None","1.19A","1l4nA-4zdnA:undetectable","1l4nA-4zdnA:20.78"],["1L5K_A_NIOA991_1","NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"THR A 864;GLY A 869;GLY A 782;PHE A 781;GLY A 785","None","1.14A","1l5kA-4zdnA:undetectable","1l5kA-4zdnA:20.78"],["1L5L_A_NIOA991_1","NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"THR A 864;GLY A 869;GLY A 782;PHE A 781;GLY A 785","None","1.16A","1l5lA-4zdnA:undetectable","1l5lA-4zdnA:20.78"],["1L5M_A_NIOA991_1","NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"THR A 864;GLY A 869;GLY A 782;PHE A 781;GLY A 785","None","1.16A","1l5mA-4zdnA:undetectable","1l5mA-4zdnA:20.78"],["1MJ2_A_SAMA2201_1","PROTEIN (METHIONINE REPRESSOR)","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"HIS A 823;ALA A 974;PHE A 969;GLY A 824","None","1.39A","1mj2B-4zdnA:undetectable","1mj2B-4zdnA:9.76"],["1MJ2_C_SAMC1200_1","PROTEIN (METHIONINE REPRESSOR)","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"HIS A 823;ALA A 974;PHE A 969;GLY A 824","None","1.39A","1mj2D-4zdnA:undetectable","1mj2D-4zdnA:9.76"],["1MJO_A_SAMA199_1","METHIONINE REPRESSOR","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"HIS A 823;ALA A 974;PHE A 969;GLY A 824","None","1.39A","1mjoB-4zdnA:undetectable","1mjoB-4zdnA:9.76"],["1MJO_B_SAMB200_0","METHIONINE REPRESSOR","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"HIS A 823;ALA A 974;PHE A 969;GLY A 824","None","1.39A","1mjoA-4zdnA:undetectable","1mjoA-4zdnA:9.76"],["1MJO_D_SAMD200_1","METHIONINE REPRESSOR","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"HIS A 823;ALA A 974;PHE A 969;GLY A 824","None","1.39A","1mjoD-4zdnA:undetectable","1mjoD-4zdnA:9.76"],["1NT5_A_DVAA6_0","GRAMICIDIN A","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",3,"ALA A1125;VAL A1127;TRP A1130","None","0.76A","1nt5A-4zdnA:undetectable","1nt5A-4zdnA:4.02"],["1NT5_B_DVAB6_0","GRAMICIDIN A","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",3,"ALA A1125;VAL A1127;TRP A1130","None","0.76A","1nt5B-4zdnA:undetectable","1nt5B-4zdnA:4.02"],["1RLB_F_REAF177_1","RETINOL BINDING PROTEIN","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"LEU A1031;ALA A1053;VAL A1034;LEU A1166;LEU A1019","None","1.13A","1rlbF-4zdnA:undetectable","1rlbF-4zdnA:13.75"],["1WG8_B_SAMB3141_0","PREDICTED S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"GLY A 678;GLY A 753;GLY A 795;ASP A 724;SER A 729","None","1.16A","1wg8B-4zdnA:undetectable","1wg8B-4zdnA:19.34"],["2A1O_A_CAMA1422_0","CYTOCHROME P450-CAM","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"TYR A 564;THR A 913;GLY A 752;VAL A 654","None","0.91A","2a1oA-4zdnA:undetectable","2a1oA-4zdnA:21.63"],["2BXE_A_1FLA2003_1","SERUM ALBUMIN","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"LEU A 741;LEU A 748;HIS A 669;LEU A 798;ALA A 805","None","1.16A","2bxeA-4zdnA:undetectable","2bxeA-4zdnA:19.80"],["2BXE_B_1FLB2003_1","SERUM ALBUMIN","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"LEU A 741;LEU A 748;HIS A 669;LEU A 798;ALA A 805","None","1.13A","2bxeB-4zdnA:undetectable","2bxeB-4zdnA:19.80"],["2BXP_A_P1ZA3001_1","SERUM ALBUMIN","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"LEU A 912;LEU A 557;LEU A 799;ALA A 749;ALA A 796","None","1.15A","2bxpA-4zdnA:undetectable","2bxpA-4zdnA:19.80"],["2CC8_A_RBFA1067_1","VNG1446H","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",3,"PHE A1142;VAL A1127;TRP A1130","None","0.57A","2cc8A-4zdnA:2.7","2cc8A-4zdnA:7.35"],["2CCB_A_RBFA1067_1","VNG1446H","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",3,"PHE A1142;VAL A1127;TRP A1130","None","0.59A","2ccbA-4zdnA:undetectable","2ccbA-4zdnA:7.35"],["2G70_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"PHE A 647;LEU A 706;ALA A 623;PHE A 622;VAL A 794","None","0.99A","2g70A-4zdnA:undetectable","2g70A-4zdnA:19.09"],["2G70_B_SAMB2002_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"PHE A 647;LEU A 706;ALA A 623;PHE A 622;VAL A 794","None","0.95A","2g70B-4zdnA:undetectable","2g70B-4zdnA:19.09"],["2G72_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"PHE A 647;LEU A 706;ALA A 623;PHE A 622;VAL A 794","None","0.90A","2g72A-4zdnA:undetectable","2g72A-4zdnA:19.09"],["2HRC_A_CHDA702_0","FERROCHELATASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"ARG A1015;LEU A1019;PRO A1161;VAL A1164","None","1.11A","2hrcA-4zdnA:undetectable","2hrcA-4zdnA:18.28"],["2PO5_B_CHDB501_0","FERROCHELATASE, MITOCHONDRIAL","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"LEU A1067;PHE A1066;LEU A1063;LEU A1166;VAL A1034","None","1.32A","2po5B-4zdnA:3.4","2po5B-4zdnA:17.98"],["2V0M_A_KLNA1500_1","CYTOCHROME P450 3A4","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"ILE A 909;ALA A 906;ARG A 624;GLU A 649;LEU A 619","None","1.41A","2v0mA-4zdnA:undetectable","2v0mA-4zdnA:19.51"],["2VX9_A_RBFA1064_1","DODECIN","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",3,"PHE A1142;VAL A1127;TRP A1130","None","0.59A","2vx9A-4zdnA:undetectable","2vx9A-4zdnA:7.15"],["3AOC_C_ERYC3402_0","ACRIFLAVINE RESISTANCE PROTEIN B","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"SER A 895;PHE A 939;ILE A 874;LEU A 789;ASP A 775","None","1.17A","3aocC-4zdnA:undetectable","3aocC-4zdnA:21.54"],["3MBG_C_ACTC800_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",3,"ASP A 639;ARG A 635;ALA A 638","None","0.79A","3mbgC-4zdnA:2.2","3mbgC-4zdnA:10.85"],["3OU6_D_SAMD300_0","SAM-DEPENDENT METHYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"LEU A 928;GLU A 923;ALA A 925;GLY A 580;LEU A 577","None","1.41A","3ou6D-4zdnA:undetectable","3ou6D-4zdnA:15.35"],["3OXW_D_017D200_1","HIV-1 PROTEASE;HIV-1 PROTEASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"ALA A 567;ASP A 566;ILE A 900;GLY A 793;VAL A 794","None","1.01A","3oxwC-4zdnA:undetectable","3oxwC-4zdnA:10.87"],["3PGH_B_FLPB701_1","CYCLOOXYGENASE-2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"VAL A 797;LEU A 560;LEU A 799;TYR A 564;GLY A 911","None","0.95A","3pghB-4zdnA:undetectable","3pghB-4zdnA:18.20"],["3PGH_D_FLPD701_1","CYCLOOXYGENASE-2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"VAL A 797;LEU A 560;LEU A 799;TYR A 564;GLY A 911","None","0.95A","3pghD-4zdnA:undetectable","3pghD-4zdnA:18.20"],["3R0L_D_ACTD127_0","PHOSPHOLIPASE A2 CB","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"PHE A 676;GLY A 718;CYH A 746;HIS A 740","None","1.21A","3r0lD-4zdnA:undetectable","3r0lD-4zdnA:9.73"],["3RR3_C_FLRC700_1","PROSTAGLANDIN G\/H SYNTHASE 2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"VAL A 797;LEU A 560;LEU A 799;TYR A 564;GLY A 911","None","0.97A","3rr3C-4zdnA:undetectable","3rr3C-4zdnA:18.65"],["3RR3_D_FLRD700_1","PROSTAGLANDIN G\/H SYNTHASE 2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"VAL A 797;LEU A 560;LEU A 799;TYR A 564;GLY A 911","None","0.98A","3rr3D-4zdnA:undetectable","3rr3D-4zdnA:18.65"],["3UBO_B_ADNB353_1","ADENOSINE KINASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"ASN A 899;ILE A 900;GLY A 791;GLY A 901;LEU A 577","None","1.09A","3uboB-4zdnA:undetectable","3uboB-4zdnA:21.44"],["3UJ7_B_SAMB302_1","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"SER A 898;ASP A 870;ASP A 936;ILE A 937","None","1.19A","3uj7B-4zdnA:undetectable","3uj7B-4zdnA:15.56"],["4JQ1_B_NPSB401_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"HIS A 977;VAL A 817;ILE A 816;LEU A 731","None","0.88A","4jq1B-4zdnA:undetectable","4jq1B-4zdnA:18.83"],["4KQI_A_NIOA403_1","NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"THR A 864;GLY A 869;GLY A 782;PHE A 781;GLY A 785","None","1.16A","4kqiA-4zdnA:undetectable","4kqiA-4zdnA:20.34"],["4LS7_A_1X9A504_1","3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"CYH A 727;HIS A 862;THR A 864;HIS A 902;GLY A 970","None","0.61A","4ls7A-4zdnA:47.6","4ls7A-4zdnA:20.09"],["4LS7_B_1X9B503_1","3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 2;3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"CYH A 727;HIS A 862;THR A 864;HIS A 902;GLY A 970","None","0.60A","4ls7A-4zdnA:47.6;4ls7B-4zdnA:47.4","4ls7A-4zdnA:20.09;4ls7B-4zdnA:20.09"],["5BS8_G_MFXG101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"ARG A1106;GLY A1105;THR A1009;GLU A1047","None;None; CL A1202 ( 4.4A);None","0.91A","5bs8A-4zdnA:undetectable;5bs8C-4zdnA:undetectable;5bs8D-4zdnA:undetectable","5bs8A-4zdnA:22.69;5bs8C-4zdnA:22.69;5bs8D-4zdnA:17.34"],["5BTA_G_MFXG101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"ARG A1106;GLY A1105;THR A1009;GLU A1047","None;None; CL A1202 ( 4.4A);None","0.91A","5btaA-4zdnA:undetectable;5btaC-4zdnA:undetectable;5btaD-4zdnA:undetectable","5btaA-4zdnA:22.27;5btaC-4zdnA:22.27;5btaD-4zdnA:17.34"],["5BTA_H_MFXH101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCACGTAA","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"ARG A1106;GLY A1105;THR A1009;GLU A1047","None;None; CL A1202 ( 4.4A);None","0.92A","5btaA-4zdnA:undetectable;5btaB-4zdnA:undetectable;5btaC-4zdnA:undetectable","5btaA-4zdnA:22.27;5btaB-4zdnA:17.34;5btaC-4zdnA:22.27"],["5BTC_G_CPFG101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"ARG A1106;GLY A1105;THR A1009;GLU A1047","None;None; CL A1202 ( 4.4A);None","0.99A","5btcA-4zdnA:undetectable;5btcC-4zdnA:undetectable;5btcD-4zdnA:undetectable","5btcA-4zdnA:22.27;5btcC-4zdnA:22.27;5btcD-4zdnA:17.34"],["5BTC_G_CPFG102_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"ARG A1106;GLY A1105;THR A1009;GLU A1047","None;None; CL A1202 ( 4.4A);None","1.01A","5btcA-4zdnA:undetectable;5btcB-4zdnA:undetectable;5btcC-4zdnA:undetectable","5btcA-4zdnA:22.27;5btcB-4zdnA:17.34;5btcC-4zdnA:22.27"],["5BTF_F_GFNF101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"ARG A1106;GLY A1105;THR A1009;GLU A1047","None;None; CL A1202 ( 4.4A);None","0.96A","5btfA-4zdnA:undetectable;5btfB-4zdnA:undetectable;5btfC-4zdnA:undetectable","5btfA-4zdnA:22.27;5btfB-4zdnA:17.34;5btfC-4zdnA:22.27"],["5BTG_E_LFXE101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCACGTAA","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"ARG A1106;GLY A1105;THR A1009;GLU A1047","None;None; CL A1202 ( 4.4A);None","0.96A","5btgA-4zdnA:undetectable;5btgB-4zdnA:undetectable;5btgC-4zdnA:undetectable","5btgA-4zdnA:22.69;5btgB-4zdnA:17.34;5btgC-4zdnA:22.69"],["5C0O_H_SAMH301_1","TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRMI","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"THR A 864;GLY A 787;HIS A 929;ASP A 870","None","1.26A","5c0oH-4zdnA:undetectable","5c0oH-4zdnA:17.31"],["5ENT_C_MIYC901_1","MULTIDRUG EFFLUX PUMP SUBUNIT ACRB,MULTIDRUG EFFLUX PUMP SUBUNIT ACRB","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"SER A 762;GLU A 792;ASN A 755;ILE A 679;ALA A 677","None","1.40A","5entC-4zdnA:0.9","5entC-4zdnA:23.28"],["5FHZ_C_REAC602_1","ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"ILE A 900;GLY A 791;PHE A 573;LEU A 619;LEU A 756","None","1.02A","5fhzC-4zdnA:undetectable","5fhzC-4zdnA:22.04"],["5IGI_A_ZITA402_2","MACROLIDE 2'-PHOSPHOTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"HIS A 921;GLU A 571;ALA A 579;TYR A 564","None","0.96A","5igiA-4zdnA:undetectable","5igiA-4zdnA:19.06"],["5IKR_B_ID8B602_1","PROSTAGLANDIN G\/H SYNTHASE 2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"VAL A 797;LEU A 560;LEU A 799;TYR A 564;GLY A 911","None","0.89A","5ikrB-4zdnA:undetectable","5ikrB-4zdnA:21.01"],["5JNC_D_ACTD305_0","CARBONIC ANHYDRASE 4","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"PRO A 634;ALA A 637;ALA A 627;ILE A 632","None","0.79A","5jncD-4zdnA:undetectable","5jncD-4zdnA:16.85"],["5JVZ_B_FLPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"VAL A 797;LEU A 560;LEU A 799;TYR A 564;GLY A 911","None","0.95A","5jvzB-4zdnA:undetectable","5jvzB-4zdnA:18.62"],["5M0O_A_EPAA502_1","TERMINAL OLEFIN-FORMING FATTY ACID DECARBOXYLASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"ILE A 632;PHE A 630;PRO A 634;ALA A 637;PHE A 625","None;EPE A1201 (-4.8A);None;None;None","1.24A","5m0oA-4zdnA:undetectable","5m0oA-4zdnA:19.44"],["5M66_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"GLN A 947;THR A 927;GLU A 860;LEU A 877","None","1.08A","5m66A-4zdnA:undetectable","5m66A-4zdnA:21.75"],["5N1T_W_CUW201_0","COPC","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",3,"HIS A 929;ASP A 775;HIS A 777","None","0.87A","5n1tW-4zdnA:undetectable","5n1tW-4zdnA:13.48"],["5NWU_A_ACAA18_1","WTFP-TAG,GP41","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"ALA A 849;GLY A 818;SER A 819;GLU A 860;LEU A 912","None","1.21A","5nwuA-4zdnA:undetectable","5nwuA-4zdnA:6.84"],["5YW0_A_ACTA410_0","UNCHARACTERIZED PROTEIN KDOO","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"GLY A 776;LEU A 789;VAL A 584;GLU A 582","None","1.48A","5yw0A-4zdnA:undetectable","5yw0A-4zdnA:19.01"],["6DWN_D_AQ4D602_0","CYTOCHROME P450 1A1","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"ILE A 859;PHE A 881;ASP A 884;ILE A 979;LEU A 846","None","1.09A","6dwnD-4zdnA:undetectable","6dwnD-4zdnA:9.03"],["6GTQ_B_ACTB207_0","DUF1778 DOMAIN-CONTAINING PROTEIN;N-ACETYLTRANSFERASE","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",4,"LEU A1166;THR A1037;GLY A 659;ARG A1042","None","1.35A","6gtqB-4zdnA:undetectable;6gtqD-4zdnA:undetectable","6gtqB-4zdnA:17.05;6gtqD-4zdnA:5.71"],["6HQB_A_PQNA2001_0","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1;PHOTOSYSTEM I REACTION CENTER SUBUNIT IX","4zdn","AT-LESS POLYKETIDE SYNTHASE","Streptomyces platensis",5,"SER A 780;GLY A 865;ALA A 773;LEU A 789;GLY A 901","None","1.35A","6hqbA-4zdnA:undetectable;6hqbJ-4zdnA:undetectable","6hqbA-4zdnA:8.90;6hqbJ-4zdnA:5.30"]]