SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zdv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 4zdv MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3A
(Homo
sapiens) 		5 / 11 LEU A  63
ILE A  35
PHE A  79
PHE A  52
ASP A  48
 None
 1.13A 2qjuA-4zdvA:
undetectable		 2qjuA-4zdvA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 4zdv MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3A
(Homo
sapiens) 		3 / 3 GLU A  19
ASP A 106
TYR A 110
 None
 0.78A 2yvlB-4zdvA:
undetectable		 2yvlB-4zdvA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 4zdv MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3A
(Homo
sapiens) 		5 / 12 VAL A  54
LEU A  47
ILE A  35
TYR A 113
LEU A  73
 None
 0.78A 5ienA-4zdvA:
undetectable		 5ienA-4zdvA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6L_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4zdv MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3A
(Homo
sapiens) 		5 / 9 ASP A  48
LEU A  47
ILE A  34
PRO A   6
ARG A  10
 None
 1.40A 5z6lA-4zdvA:
undetectable		 5z6lA-4zdvA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4zdv MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3A
(Homo
sapiens) 		4 / 5 ASP A 106
ILE A  23
ASN A  84
TYR A 110
 None
 0.93A 6a93B-4zdvA:
undetectable		 6a93B-4zdvA:
16.12