SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zej'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.20A 1gtnO-4zejA:
undetectable
1gtnP-4zejA:
undetectable		 1gtnO-4zejA:
18.55
1gtnP-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 7 TYR A 116
THR A  56
THR A  49
SER A  75
 None
 1.23A 1tv8B-4zejA:
undetectable		 1tv8B-4zejA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 1utdT-4zejA:
undetectable
1utdU-4zejA:
undetectable		 1utdT-4zejA:
18.55
1utdU-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 6 SER A  21
ASP A  55
SER A  33
VAL A  31
 None
 1.19A 2hdnI-4zejA:
undetectable
2hdnJ-4zejA:
undetectable
2hdnL-4zejA:
undetectable		 2hdnI-4zejA:
11.21
2hdnJ-4zejA:
19.88
2hdnL-4zejA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 6 SER A  33
VAL A  31
SER A  21
ASP A  55
 None
 1.24A 2hdnJ-4zejA:
undetectable
2hdnK-4zejA:
undetectable
2hdnL-4zejA:
undetectable		 2hdnJ-4zejA:
19.88
2hdnK-4zejA:
11.21
2hdnL-4zejA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 5 ALA A 183
LEU A 154
GLY A 156
THR A 102
 None
 0.94A 3dl9A-4zejA:
undetectable		 3dl9A-4zejA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 12 ARG A 161
HIS A 139
ALA A 186
HIS A  77
ASP A  81
 CL  A 305 (-3.5A)
ZN  A 302 (-3.3A)
None
ZN  A 302 ( 3.3A)
ZN  A 301 ( 2.5A)
 1.06A 4aqlA-4zejA:
undetectable		 4aqlA-4zejA:
18.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1D_A_X8ZA350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		6 / 9 TRP A  51
HIS A  79
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.45A 4c1dA-4zejA:
33.8		 4c1dA-4zejA:
34.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		7 / 10 TRP A  51
HIS A  77
HIS A  79
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 302 ( 3.3A)
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.38A 4c1dB-4zejA:
33.8		 4c1dB-4zejA:
34.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		7 / 11 VAL A  25
HIS A  77
HIS A  79
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 302 ( 3.3A)
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.37A 4c1fA-4zejA:
37.0
4c1fB-4zejA:
36.3		 4c1fA-4zejA:
47.41
4c1fB-4zejA:
47.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		7 / 9 HIS A  77
HIS A  79
ASP A  81
HIS A 139
CYH A 158
GLY A 169
HIS A 200
 ZN  A 302 ( 3.3A)
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
CL  A 305 ( 4.5A)
ZN  A 301 ( 3.3A)
 0.58A 4c1hA-4zejA:
33.1		 4c1hA-4zejA:
36.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		7 / 9 TRP A  51
HIS A  77
ASP A  81
HIS A 139
CYH A 158
GLY A 169
HIS A 200
 None
ZN  A 302 ( 3.3A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
CL  A 305 ( 4.5A)
ZN  A 301 ( 3.3A)
 0.88A 4c1hA-4zejA:
33.1		 4c1hA-4zejA:
36.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_A_X8ZA301_1
(BETA-LACTAMASE NDM-1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 9 TRP A  51
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.93A 4exsA-4zejA:
31.8		 4exsA-4zejA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_A_X8ZA301_1
(BETA-LACTAMASE NDM-1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		6 / 9 VAL A  31
HIS A  79
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.37A 4exsA-4zejA:
31.8		 4exsA-4zejA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 8 TRP A  51
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.94A 4exsB-4zejA:
32.1		 4exsB-4zejA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		6 / 8 VAL A  31
HIS A  79
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.40A 4exsB-4zejA:
32.1		 4exsB-4zejA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 6 THR A 140
GLY A 138
ASN A 143
GLY A 169
 None
None
None
CL  A 305 ( 4.5A)
 0.89A 4fjpA-4zejA:
undetectable		 4fjpA-4zejA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 11 LEU A  36
VAL A 196
LEU A 154
LEU A  18
LEU A 148
 None
 1.24A 4or0B-4zejA:
undetectable		 4or0B-4zejA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 8 TRP A  51
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.97A 5a5zA-4zejA:
32.4		 5a5zA-4zejA:
29.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		6 / 8 VAL A  31
HIS A  79
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.33A 5a5zA-4zejA:
32.4		 5a5zA-4zejA:
29.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 7 HIS A 139
CYH A 158
GLY A 169
HIS A 200
 ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
CL  A 305 ( 4.5A)
ZN  A 301 ( 3.3A)
 0.35A 5a5zC-4zejA:
32.1		 5a5zC-4zejA:
29.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 11 HIS A  77
HIS A  79
ASP A  81
HIS A 139
HIS A 200
 ZN  A 302 ( 3.3A)
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 3.3A)
 0.74A 5ayaA-4zejA:
16.5		 5ayaA-4zejA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.20A 5eeuO-4zejA:
undetectable
5eeuP-4zejA:
undetectable		 5eeuO-4zejA:
18.55
5eeuP-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.20A 5eeuQ-4zejA:
undetectable
5eeuR-4zejA:
undetectable		 5eeuQ-4zejA:
18.55
5eeuR-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5eevO-4zejA:
undetectable
5eevP-4zejA:
undetectable		 5eevO-4zejA:
18.55
5eevP-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.20A 5eevQ-4zejA:
undetectable
5eevR-4zejA:
undetectable		 5eevQ-4zejA:
18.55
5eevR-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5eewO-4zejA:
undetectable
5eewP-4zejA:
undetectable		 5eewO-4zejA:
18.55
5eewP-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5eexO-4zejA:
undetectable
5eexP-4zejA:
undetectable		 5eexO-4zejA:
18.55
5eexP-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5eeyO-4zejA:
undetectable
5eeyP-4zejA:
undetectable		 5eeyO-4zejA:
18.55
5eeyP-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5eezO-4zejA:
undetectable
5eezP-4zejA:
undetectable		 5eezO-4zejA:
18.55
5eezP-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5ef0O-4zejA:
undetectable
5ef0P-4zejA:
undetectable		 5ef0O-4zejA:
18.55
5ef0P-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5ef1O-4zejA:
undetectable
5ef1P-4zejA:
undetectable		 5ef1O-4zejA:
18.55
5ef1P-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5ef2O-4zejA:
undetectable
5ef2P-4zejA:
undetectable		 5ef2O-4zejA:
18.55
5ef2P-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		5 / 10 GLY A 156
ALA A 186
HIS A 139
THR A 212
ALA A 183
 None
None
ZN  A 302 (-3.3A)
None
None
 1.19A 5ef3O-4zejA:
undetectable
5ef3P-4zejA:
undetectable		 5ef3O-4zejA:
18.55
5ef3P-4zejA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 8 VAL A 146
LEU A 118
THR A  99
ALA A  98
 None
 0.90A 5tt3H-4zejA:
undetectable		 5tt3H-4zejA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 6 THR A 117
ASN A 103
ILE A  86
GLU A 112
 None
 1.28A 5uigA-4zejA:
undetectable		 5uigA-4zejA:
18.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		6 / 8 TRP A  51
HIS A  79
ASP A  81
HIS A 139
CYH A 158
HIS A 200
 None
ZN  A 302 (-3.1A)
ZN  A 301 ( 2.5A)
ZN  A 302 (-3.3A)
ZN  A 301 ( 2.1A)
ZN  A 301 ( 3.3A)
 0.91A 5zj8A-4zejA:
17.0		 5zj8A-4zejA:
31.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4zej METALLO-BETA-LACTAMA
SE
(Pseudomonas
stutzeri) 		4 / 7 THR A  96
ARG A  82
HIS A 139
ASP A  48
 None
ZN  A 301 ( 4.5A)
ZN  A 302 (-3.3A)
None
 1.12A 6mn4E-4zejA:
undetectable		 6mn4E-4zejA:
22.86