SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zem'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CL5_A_SAMA1217_1 (CATECHOL O-METHYLTRANSFERASE)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	4 / 4	SER A 346 GLU A 339 GLN A 416 ASP A 343	None	1.34A	2cl5A-4zemA: 0.0	2cl5A-4zemA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CL5_B_SAMB1217_1 (CATECHOL O-METHYLTRANSFERASE)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	SER A 346 GLU A 339 GLN A 416 ASP A 343	None	1.35A	2cl5B-4zemA: 4.9	2cl5B-4zemA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D06_B_ESTB305_1 (SULFOTRANSFERASE 1A1)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	5 / 10	PRO A 341 ALA A 298 VAL A 309 TYR A 386 PHE A 296	None	1.19A	2d06B-4zemA: 1.7	2d06B-4zemA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VOU_B_ACTB1391_0 (2,6-DIHYDROXYPYRIDIN E HYDROXYLASE)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	PRO A 341 GLY A 306 TYR A 377	None	0.71A	2vouB-4zemA: undetectable	2vouB-4zemA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VOU_C_ACTC1391_0 (2,6-DIHYDROXYPYRIDIN E HYDROXYLASE)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	PRO A 341 GLY A 306 TYR A 377	None	0.72A	2vouC-4zemA: undetectable	2vouC-4zemA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZVJ_A_SAMA301_1 (CATECHOL O-METHYLTRANSFERASE)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	SER A 346 GLU A 339 GLN A 416 ASP A 343	None	1.32A	2zvjA-4zemA: 4.1	2zvjA-4zemA: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_C_ACHC301_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	4 / 8	TYR A 220 THR A 276 TYR A 287 ARG A 266	None	1.21A	3wipC-4zemA: undetectable 3wipD-4zemA: undetectable	3wipC-4zemA: 20.79 3wipD-4zemA: 20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EB6_C_VLBC503_1 (TUBULIN BETA CHAIN TUBULIN ALPHA CHAIN)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	VAL A 327 THR A 394 PRO A 392 ILE A 207 ILE A 213	None	1.28A	4eb6B-4zemA: 3.2 4eb6C-4zemA: 3.1	4eb6B-4zemA: 22.98 4eb6C-4zemA: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OJB_A_198A1001_1 (ANDROGEN RECEPTOR)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 197 GLY A  47 GLN A  51 LEU A  12 ARG A  20	None	1.40A	4ojbA-4zemA: undetectable	4ojbA-4zemA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKX_A_198A1002_1 (ANDROGEN RECEPTOR)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	LEU A 197 GLY A  47 GLN A  51 LEU A  12 ARG A  20	None	1.43A	4okxA-4zemA: undetectable	4okxA-4zemA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X20_D_LOCD502_2 (TUBULIN BETA CHAIN)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	5 / 11	LEU A 265 LYS A 228 ALA A 223 VAL A 245 ILE A 295	None	1.13A	4x20D-4zemA: 3.1	4x20D-4zemA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHR_B_SAMB303_1 (CATECHOL O-METHYLTRANSFERASE)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	4 / 5	SER A 346 GLU A 339 GLN A 416 ASP A 343	None	1.36A	5fhrB-4zemA: undetectable	5fhrB-4zemA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_A_CELA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	4 / 6	VAL A 274 LEU A 222 ARG A 290 ILE A 288	None	1.00A	5jw1A-4zemA: 2.5	5jw1A-4zemA: 21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_G_CVIG301_0 (REGULATORY PROTEIN TETR)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	GLN A  51 ALA A  48 ILE A 196 ARG A  95 VAL A  88	None	1.28A	5vlmG-4zemA: 2.4	5vlmG-4zemA: 20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_G_CVIG301_0 (REGULATORY PROTEIN TETR)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	GLN A  51 LEU A 197 ILE A 196 ARG A  95 VAL A  88	None	1.20A	5vlmG-4zemA: 2.4	5vlmG-4zemA: 20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_A_C2FA3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	5 / 12	GLU A 194 VAL A  72 LEU A  68 VAL A  96 ILE A 193	None	0.84A	5vopA-4zemA: 2.4	5vopA-4zemA: 24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_0 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	4 / 8	ILE A 295 GLN A 214 GLU A 212 SER A 209	None	1.03A	6fbvC-4zemA: undetectable	6fbvC-4zemA: 16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	7DFR_A_FOLA161_1 (DIHYDROFOLATE REDUCTASE)	4zem	TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN,TRANSLATION INITIATION FACTOR EIF2B-LIKE PROTEIN (Chaetomium thermophilum)	3 / 3	ASP A 198 LEU A 197 ARG A  20	None	0.84A	7dfrA-4zemA: undetectable	7dfrA-4zemA: 16.96