SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zet'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 4zet C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER C
(Homo
sapiens) 		5 / 12 ILE A 182
GLY A 143
ILE A 205
SER A 145
GLU A 178
 None
None
None
None
MAN  A 303 (-2.4A)
 1.26A 1sg9A-4zetA:
undetectable		 1sg9A-4zetA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 4zet C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER C
(Homo
sapiens) 		3 / 3 TRP A 153
TRP A 168
THR A 166
 None
 1.48A 4bboB-4zetA:
undetectable		 4bboB-4zetA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 4zet C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER C
(Homo
sapiens) 		3 / 3 SER A 112
ASP A 117
GLN A 158
 None
 0.89A 4oltA-4zetA:
undetectable
4oltB-4zetA:
undetectable		 4oltA-4zetA:
18.33
4oltB-4zetA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 4zet C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER C
(Homo
sapiens) 		3 / 3 GLN A 158
SER A 112
ASP A 117
 None
 0.86A 4qwpA-4zetA:
undetectable
4qwpB-4zetA:
undetectable		 4qwpA-4zetA:
18.33
4qwpB-4zetA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 4zet C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER C
(Homo
sapiens) 		4 / 6 ILE A 130
TYR A  95
PHE A  90
THR A 159
 None
 1.35A 5g08A-4zetA:
undetectable		 5g08A-4zetA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 4zet C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER C
(Homo
sapiens) 		5 / 12 ILE A 182
LEU A 144
GLY A 143
PHE A 141
ASP A 177
 None
 1.06A 5x66A-4zetA:
undetectable
5x66B-4zetA:
undetectable		 5x66A-4zetA:
18.06
5x66B-4zetA:
18.06