SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zev'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 4zev PFHAD1
(Plasmodium
falciparum) 		4 / 6 VAL A  57
VAL A  39
ASN A  43
ILE A  48
 None
 0.88A 1e06A-4zevA:
undetectable		 1e06A-4zevA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4zev PFHAD1
(Plasmodium
falciparum) 		3 / 3 HIS A   0
ASP A   6
ASN A  16
 None
 0.67A 1wg8B-4zevA:
undetectable		 1wg8B-4zevA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 4zev PFHAD1
(Plasmodium
falciparum) 		5 / 12 GLY A 237
LEU A 249
LEU A 246
ILE A  23
SER A  46
 None
 1.25A 1zq9A-4zevA:
undetectable		 1zq9A-4zevA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4zev PFHAD1
(Plasmodium
falciparum) 		4 / 5 ALA A 266
ALA A  27
ALA A  60
VAL A 219
 None
M6P  A 302 (-3.3A)
None
None
 0.75A 2nyrB-4zevA:
5.0		 2nyrB-4zevA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 4zev PFHAD1
(Plasmodium
falciparum) 		3 / 3 TYR A  88
MET A 236
LEU A  32
 None
 0.80A 3vw1D-4zevA:
undetectable		 3vw1D-4zevA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 4zev PFHAD1
(Plasmodium
falciparum) 		4 / 8 VAL A 198
VAL A 206
ILE A 124
PHE A 174
 None
 0.50A 3warA-4zevA:
undetectable		 3warA-4zevA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4zev PFHAD1
(Plasmodium
falciparum) 		5 / 9 LEU A 234
ILE A  24
ILE A  23
TYR A 225
ILE A  55
 None
 1.15A 3zosA-4zevA:
undetectable		 3zosA-4zevA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4zev PFHAD1
(Plasmodium
falciparum) 		5 / 12 VAL A  71
ILE A  81
TYR A  88
VAL A  57
LEU A  33
 None
 1.29A 4a84A-4zevA:
undetectable		 4a84A-4zevA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 4zev PFHAD1
(Plasmodium
falciparum) 		5 / 12 LEU A 208
ILE A 124
TYR A 148
GLU A 152
LEU A 176
 None
None
M6P  A 302 ( 4.9A)
M6P  A 302 (-2.2A)
None
 1.20A 5ienB-4zevA:
undetectable		 5ienB-4zevA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 4zev PFHAD1
(Plasmodium
falciparum) 		4 / 7 VAL A 198
VAL A 206
ILE A 124
PHE A 174
 None
 0.60A 5ywmX-4zevA:
undetectable		 5ywmX-4zevA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4zev PFHAD1
(Plasmodium
falciparum) 		4 / 5 ASP A 104
ILE A  87
ASN A 108
TYR A 170
 None
 1.11A 6a93B-4zevA:
undetectable		 6a93B-4zevA:
20.63