SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zfq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		3 / 3 VAL A 408
TRP A 206
TRP A 220
 None
None
PEG  A 501 ( 4.8A)
 1.42A 1c4dA-4zfqA:
undetectable
1c4dB-4zfqA:
undetectable		 1c4dA-4zfqA:
3.82
1c4dB-4zfqA:
3.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 8 ASN A 362
GLY A 291
THR A 300
GLY A 338
 None
None
None
DWZ  A 503 (-2.8A)
 0.80A 1jr1B-4zfqA:
undetectable		 1jr1B-4zfqA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.68A 1usqA-4zfqA:
undetectable		 1usqA-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 6 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.68A 1usqB-4zfqA:
undetectable		 1usqB-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 6 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.67A 1usqC-4zfqA:
undetectable		 1usqC-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 6 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.69A 1usqD-4zfqA:
undetectable		 1usqD-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 6 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.68A 1usqE-4zfqA:
undetectable		 1usqE-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 6 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.69A 2jkjA-4zfqA:
undetectable		 2jkjA-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 6 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.70A 2jkjB-4zfqA:
undetectable		 2jkjB-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 6 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.69A 2jkjC-4zfqA:
undetectable		 2jkjC-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.69A 2jklA-4zfqA:
undetectable		 2jklA-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 6 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.69A 2jklB-4zfqA:
undetectable		 2jklB-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.69A 2jklC-4zfqA:
undetectable		 2jklC-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.71A 2jklD-4zfqA:
undetectable		 2jklD-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 7 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.70A 2jklF-4zfqA:
undetectable		 2jklF-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		3 / 3 LYS A 187
ARG A 217
VAL A 218
 None
 1.00A 2r2vC-4zfqA:
undetectable
2r2vD-4zfqA:
undetectable		 2r2vC-4zfqA:
7.29
2r2vD-4zfqA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 124
ILE A  84
LEU A  98
PHE A 149
 PEG  A 502 ( 3.3A)
None
None
None
 0.91A 4ejjD-4zfqA:
undetectable		 4ejjD-4zfqA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 8 ASN A 362
GLY A 291
THR A 300
GLY A 338
 None
None
None
DWZ  A 503 (-2.8A)
 0.75A 4fo4B-4zfqA:
undetectable		 4fo4B-4zfqA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		5 / 9 ALA A 375
GLY A 171
ILE A 172
ILE A 334
VAL A 332
 None
 0.99A 4nptA-4zfqA:
undetectable		 4nptA-4zfqA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		3 / 3 SER A 271
TYR A 290
ASP A 285
 None
 0.81A 4rp8C-4zfqA:
undetectable		 4rp8C-4zfqA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		4 / 4 VAL A 265
VAL A 276
TYR A 371
GLN A 370
 None
 1.46A 5qgpA-4zfqA:
undetectable		 5qgpA-4zfqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4zfq L,D-TRANSPEPTIDASE 5
(Mycobacterium
tuberculosis) 		3 / 3 VAL A 170
ALA A 174
GLN A 168
 None
 0.69A 6gb9A-4zfqA:
undetectable		 6gb9A-4zfqA:
23.40