SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zgf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QE6_A_JN3A1001_1
(BILE ACID RECEPTOR)		 4zgf UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 MET A  57
ALA A  56
HIS A  59
ARG A  70
ILE A  76
 None
 1.18A 4qe6A-4zgfA:
undetectable		 4qe6A-4zgfA:
19.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 4zgf UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 4 VAL A 144
ALA A 159
ASN A 161
GLN A 163
 None
BEZ  A 210 (-3.4A)
BEZ  A 210 (-3.9A)
BEZ  A 210 (-3.2A)
 0.00A 4zgfA-4zgfA:
30.6		 4zgfA-4zgfA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 4zgf UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 ASP A  86
TRP A 102
THR A  88
THR A  82
 P6G  A 207 ( 4.8A)
None
P6G  A 207 (-4.0A)
P6G  A 205 ( 4.9A)
 1.47A 5b6iB-4zgfA:
undetectable		 5b6iB-4zgfA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4zgf UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 SER A  31
ALA A  30
HIS A 160
LEU A 145
 None
None
P6G  A 205 ( 3.9A)
None
 1.11A 5dzkB-4zgfA:
undetectable
5dzkP-4zgfA:
undetectable		 5dzkB-4zgfA:
21.89
5dzkP-4zgfA:
1.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4zgf UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 SER A  31
ALA A  30
HIS A 160
LEU A 145
 None
None
P6G  A 205 ( 3.9A)
None
 1.40A 5dzkf-4zgfA:
undetectable
5dzkt-4zgfA:
undetectable		 5dzkf-4zgfA:
21.89
5dzkt-4zgfA:
1.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4zgf UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A  27
GLY A  32
THR A  88
TRP A 102
 None
P6G  A 205 (-3.3A)
P6G  A 207 (-4.0A)
None
 0.90A 5flcB-4zgfA:
undetectable		 5flcB-4zgfA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4zgf UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A  27
GLY A  32
THR A  88
TRP A 102
 None
P6G  A 205 (-3.3A)
P6G  A 207 (-4.0A)
None
 0.91A 5flcF-4zgfA:
undetectable		 5flcF-4zgfA:
8.80