SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zhy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 4zhy YFIR
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 174
VAL A 176
TRP A  61
 None
 0.94A 1av2A-4zhyA:
undetectable
1av2B-4zhyA:
undetectable		 1av2A-4zhyA:
9.73
1av2B-4zhyA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 4zhy YFIR
(Pseudomonas
aeruginosa) 		4 / 4 HIS A 133
ALA A 131
PHE A 127
GLY A 107
 None
 1.30A 1mjoA-4zhyA:
undetectable		 1mjoA-4zhyA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4zhy YFIR
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 127
ILE A 113
GLY A 116
GLY A  74
 None
 0.81A 2qx6A-4zhyA:
3.2
2qx6B-4zhyA:
2.1		 2qx6A-4zhyA:
21.93
2qx6B-4zhyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 4zhy YFIR
(Pseudomonas
aeruginosa) 		4 / 9 ILE A 113
ARG A  99
ALA A 100
VAL A  73
 None
None
SO4  A 201 (-3.6A)
None
 0.90A 2vufB-4zhyA:
undetectable		 2vufB-4zhyA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 4zhy YFIR
(Pseudomonas
aeruginosa) 		4 / 4 VAL A  51
ALA A  47
ASN A  46
GLN A  43
 None
 1.43A 4zgfA-4zhyA:
undetectable		 4zgfA-4zhyA:
21.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EB3_A_UEGA202_1
(YFIR)		 4zhy YFIR
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 166
ILE A 169
PRO A 178
LEU A 181
 None
 0.64A 5eb3A-4zhyA:
30.4		 5eb3A-4zhyA:
82.11