SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zi6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 8 GLU A 403
LEU A 291
ALA A 294
LEU A 295
 None
 0.84A 1hwiB-4zi6A:
undetectable		 1hwiB-4zi6A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 8 GLU A 403
LEU A 291
ALA A 294
LEU A 295
 None
 0.84A 1hwiC-4zi6A:
undetectable		 1hwiC-4zi6A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 PHE A 442
ALA A 348
PHE A 446
SER A 328
 None
 1.02A 1lqtA-4zi6A:
2.2		 1lqtA-4zi6A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 PHE A 442
ALA A 348
PHE A 446
SER A 328
 None
 1.03A 1lquA-4zi6A:
2.8		 1lquA-4zi6A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 10 LEU A 347
ALA A 287
VAL A 346
LEU A 260
ASP A 459
 None
None
None
ZN  A 501 ( 4.8A)
None
 1.29A 1rlbE-4zi6A:
undetectable		 1rlbE-4zi6A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.41A 2dyrN-4zi6A:
undetectable
2dyrW-4zi6A:
undetectable		 2dyrN-4zi6A:
22.57
2dyrW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.31A 2eimJ-4zi6A:
undetectable		 2eimJ-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.29A 2eimW-4zi6A:
undetectable		 2eimW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 6 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.41A 2einN-4zi6A:
undetectable
2einW-4zi6A:
undetectable		 2einN-4zi6A:
22.57
2einW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A 492
VAL A 256
ASP A 364
GLY A 306
PRO A 359
 None
 1.11A 2f8lA-4zi6A:
2.1		 2f8lA-4zi6A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 PHE A 475
TYR A 465
ALA A 461
ALA A 280
GLY A 370
 None
 1.21A 2igtC-4zi6A:
2.3		 2igtC-4zi6A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 ILE A   4
VAL A  78
LEU A  20
PHE A  22
ALA A 111
 None
 1.31A 2jj8C-4zi6A:
undetectable		 2jj8C-4zi6A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 LEU A 174
LEU A 120
TYR A 166
MET A   1
 None
 1.18A 2w8yA-4zi6A:
undetectable		 2w8yA-4zi6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 8 ALA A 163
ALA A 167
THR A 171
LEU A 118
 None
 0.95A 2wx2B-4zi6A:
undetectable		 2wx2B-4zi6A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A 260
ASP A 281
LYS A 270
ASP A 340
LEU A 368
 ZN  A 501 ( 4.8A)
ZN  A 501 (-2.4A)
ZN  A 502 (-3.6A)
ZN  A 502 (-2.9A)
BCT  A 503 (-4.5A)
 1.24A 2zj0A-4zi6A:
undetectable		 2zj0A-4zi6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.38A 3ablA-4zi6A:
0.2
3ablJ-4zi6A:
undetectable		 3ablA-4zi6A:
22.57
3ablJ-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.56A 3ag1J-4zi6A:
undetectable		 3ag1J-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 6 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.51A 3ag1N-4zi6A:
undetectable
3ag1W-4zi6A:
undetectable		 3ag1N-4zi6A:
22.57
3ag1W-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.38A 3ag2J-4zi6A:
undetectable		 3ag2J-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 8 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.42A 3ag3N-4zi6A:
0.7
3ag3W-4zi6A:
undetectable		 3ag3N-4zi6A:
22.57
3ag3W-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.39A 3ag4J-4zi6A:
undetectable		 3ag4J-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 GLU A 303
LEU A 206
LEU A 292
GLY A 306
HIS A 241
 None
 1.38A 3g1uA-4zi6A:
undetectable		 3g1uA-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A 260
ASP A 281
LYS A 270
ASP A 340
LEU A 368
 ZN  A 501 ( 4.8A)
ZN  A 501 (-2.4A)
ZN  A 502 (-3.6A)
ZN  A 502 (-2.9A)
BCT  A 503 (-4.5A)
 1.20A 3glqA-4zi6A:
undetectable		 3glqA-4zi6A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 GLY A 284
GLY A 257
ALA A 480
ALA A 464
LEU A 260
 None
None
None
None
ZN  A 501 ( 4.8A)
 1.26A 3mteA-4zi6A:
undetectable		 3mteA-4zi6A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A  70
GLY A  61
ALA A  60
ALA A  77
LEU A  20
 None
 1.12A 3p5nA-4zi6A:
undetectable		 3p5nA-4zi6A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A  70
GLY A  61
ALA A  60
ALA A  77
LEU A  20
 None
 1.13A 3p5nB-4zi6A:
undetectable		 3p5nB-4zi6A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 SER A 381
THR A 367
GLY A 283
ALA A 464
GLY A 481
 None
 1.14A 3tegA-4zi6A:
undetectable		 3tegA-4zi6A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 6 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.40A 3wg7N-4zi6A:
0.4
3wg7W-4zi6A:
undetectable		 3wg7N-4zi6A:
22.57
3wg7W-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 LYS A 214
LEU A 216
GLU A 217
LEU A 225
 None
 1.29A 4k4yA-4zi6A:
undetectable		 4k4yA-4zi6A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 4 LYS A 214
LEU A 216
GLU A 217
LEU A 225
 None
 1.31A 4k4yE-4zi6A:
0.0		 4k4yE-4zi6A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 LYS A 214
LEU A 216
GLU A 217
LEU A 225
 None
 1.31A 4k4yI-4zi6A:
0.1		 4k4yI-4zi6A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 ALA A 366
GLY A 284
ASP A 356
ASP A 364
 None
 0.90A 4n48A-4zi6A:
undetectable		 4n48A-4zi6A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 LEU A 441
LEU A 408
MET A 384
THR A 369
VAL A 373
 None
 1.47A 4okxA-4zi6A:
undetectable		 4okxA-4zi6A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 ALA A 160
ILE A   4
LEU A 112
PHE A 113
 None
 1.00A 4uymA-4zi6A:
0.3		 4uymA-4zi6A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		3 / 3 THR A 369
HIS A 413
LEU A 417
 None
 0.71A 5axdA-4zi6A:
undetectable		 5axdA-4zi6A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.35A 5b1bN-4zi6A:
undetectable
5b1bW-4zi6A:
undetectable		 5b1bN-4zi6A:
22.57
5b1bW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.37A 5b3sN-4zi6A:
0.5
5b3sW-4zi6A:
undetectable		 5b3sN-4zi6A:
22.57
5b3sW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 GLU A 312
THR A 311
GLU A 342
THR A 339
 None
None
ZN  A 501 (-2.5A)
None
 1.20A 5hm8A-4zi6A:
undetectable		 5hm8A-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 GLU A 312
THR A 311
GLU A 342
THR A 339
 None
None
ZN  A 501 (-2.5A)
None
 1.19A 5hm8B-4zi6A:
undetectable		 5hm8B-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 GLU A 312
THR A 311
GLU A 342
THR A 339
 None
None
ZN  A 501 (-2.5A)
None
 1.19A 5hm8C-4zi6A:
undetectable		 5hm8C-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 GLU A 312
THR A 311
GLU A 342
THR A 339
 None
None
ZN  A 501 (-2.5A)
None
 1.19A 5hm8D-4zi6A:
undetectable		 5hm8D-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 GLU A 312
THR A 311
GLU A 342
THR A 339
 None
None
ZN  A 501 (-2.5A)
None
 1.19A 5hm8E-4zi6A:
undetectable		 5hm8E-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 GLU A 312
THR A 311
GLU A 342
THR A 339
 None
None
ZN  A 501 (-2.5A)
None
 1.19A 5hm8F-4zi6A:
undetectable		 5hm8F-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 GLU A 312
THR A 311
GLU A 342
THR A 339
 None
None
ZN  A 501 (-2.5A)
None
 1.02A 5hm8G-4zi6A:
undetectable		 5hm8G-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 GLU A 312
THR A 311
GLU A 342
THR A 339
 None
None
ZN  A 501 (-2.5A)
None
 1.19A 5hm8H-4zi6A:
undetectable		 5hm8H-4zi6A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.42A 5iy5N-4zi6A:
0.3
5iy5W-4zi6A:
undetectable		 5iy5N-4zi6A:
22.57
5iy5W-4zi6A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 LEU A 260
SER A 286
ILE A 187
ASN A 235
 ZN  A 501 ( 4.8A)
None
None
None
 0.97A 5n5dA-4zi6A:
2.2		 5n5dA-4zi6A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.55A 5w97J-4zi6A:
undetectable		 5w97J-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.41A 5wauJ-4zi6A:
undetectable		 5wauJ-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.50A 5x19J-4zi6A:
undetectable		 5x19J-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.60A 5x1bJ-4zi6A:
undetectable		 5x1bJ-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.47A 5x1bW-4zi6A:
undetectable		 5x1bW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.54A 5x1fW-4zi6A:
undetectable		 5x1fW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 12 GLY A 309
GLY A 284
GLY A 257
ALA A 464
ASP A 281
 None
None
None
None
ZN  A 501 (-2.4A)
 0.92A 5x7fA-4zi6A:
undetectable		 5x7fA-4zi6A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 7 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.64A 5xdqA-4zi6A:
undetectable
5xdqJ-4zi6A:
undetectable		 5xdqA-4zi6A:
22.57
5xdqJ-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.40A 5z86J-4zi6A:
undetectable		 5z86J-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 6 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.38A 5z86N-4zi6A:
undetectable
5z86W-4zi6A:
undetectable		 5z86N-4zi6A:
22.57
5z86W-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 8 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.43A 5zcoA-4zi6A:
undetectable
5zcoJ-4zi6A:
undetectable		 5zcoA-4zi6A:
22.57
5zcoJ-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 6 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.40A 5zcoN-4zi6A:
undetectable
5zcoW-4zi6A:
undetectable		 5zcoN-4zi6A:
22.57
5zcoW-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 6 CYH A  75
TYR A 166
LEU A 174
SER A 401
 None
 1.41A 6a7pB-4zi6A:
undetectable		 6a7pB-4zi6A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		5 / 10 LEU A 295
ALA A 302
GLU A 107
SER A 397
PHE A 394
 None
 1.26A 6b89B-4zi6A:
undetectable		 6b89B-4zi6A:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.59A 6nknJ-4zi6A:
undetectable		 6nknJ-4zi6A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zi6 CYTOSOL
AMINOPEPTIDASE
(Helicobacter
pylori) 		4 / 5 TYR A 166
MET A 170
THR A 171
LEU A 174
 None
 0.62A 6nknW-4zi6A:
undetectable		 6nknW-4zi6A:
9.28