SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4zij THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Escherichia
coli) 		5 / 10 ALA A 125
ALA A 105
ILE A 108
LEU A  92
PHE A 112
 None
 1.12A 3fl9A-4zijA:
undetectable		 3fl9A-4zijA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 4zij THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Escherichia
coli) 		5 / 10 ALA A 125
ALA A 105
ILE A 108
LEU A  92
PHE A 112
 None
 1.15A 3fl9F-4zijA:
undetectable		 3fl9F-4zijA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zij THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Escherichia
coli) 		4 / 6 GLN A  74
PHE A 112
LEU A  92
PHE A  28
 None
 1.17A 5b1bC-4zijA:
undetectable
5b1bJ-4zijA:
undetectable		 5b1bC-4zijA:
19.69
5b1bJ-4zijA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 4zij THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Escherichia
coli) 		5 / 12 VAL A  16
VAL A  46
ALA A 179
PHE A 154
LEU A  12
 None
 1.48A 6a7pB-4zijA:
undetectable		 6a7pB-4zijA:
15.44