SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ziu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 LEU A1188
THR A1254
GLU A1249
LEU A1231
GLY A1238
 None
 1.47A 1d4fD-4ziuA:
undetectable		 1d4fD-4ziuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 PHE A1240
LEU A1283
VAL A1315
VAL A1257
 None
 0.97A 1e7aB-4ziuA:
undetectable		 1e7aB-4ziuA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 GLY A1186
CYH A1187
LEU A1546
MET A1634
TYR A1256
 None
 1.45A 1fm6D-4ziuA:
undetectable		 1fm6D-4ziuA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 4 LEU A1569
ILE A1511
ARG A1509
TRP A1533
 None
 1.46A 1ie9A-4ziuA:
undetectable		 1ie9A-4ziuA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 ILE A1227
LEU A1231
PHE A1240
GLY A1279
 None
 1.01A 1os6A-4ziuA:
undetectable		 1os6A-4ziuA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ARG A1124
TYR A1185
LEU A1557
LEU A1551
TYR A1614
 None
 1.46A 1p33B-4ziuA:
undetectable		 1p33B-4ziuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 ARG A1124
TYR A1185
LEU A1557
LEU A1551
TYR A1614
 None
 1.44A 1p33C-4ziuA:
undetectable		 1p33C-4ziuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 4 THR A1158
GLY A1034
ASP A1035
ALA A1126
 None
 1.20A 1sg9A-4ziuA:
undetectable		 1sg9A-4ziuA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 SER A1385
GLN A1416
SER A1384
LEU A1341
GLY A1340
 None
 0.87A 1uakA-4ziuA:
undetectable		 1uakA-4ziuA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 GLY A1186
CYH A1187
LEU A1546
MET A1634
TYR A1256
 None
 1.47A 1zgyA-4ziuA:
undetectable		 1zgyA-4ziuA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 ASP A1259
PHE A1196
ARG A1263
 None
 0.82A 2a3aA-4ziuA:
undetectable		 2a3aA-4ziuA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 11 LEU A1423
LEU A1386
LEU A1413
LEU A1431
ARG A1175
 None
 0.94A 2ceoA-4ziuA:
undetectable		 2ceoA-4ziuA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 TYR A1256
THR A1425
GLY A1194
THR A1191
ALA A1192
 None
 1.36A 2coiA-4ziuA:
undetectable
2coiB-4ziuA:
undetectable		 2coiA-4ziuA:
21.31
2coiB-4ziuA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		6 / 10 LEU A1649
VAL A1626
ASP A1035
GLY A1554
LEU A1555
LEU A1551
 None
 1.31A 2v3kA-4ziuA:
undetectable		 2v3kA-4ziuA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 THR A1620
GLU A1556
PHE A1030
ILE A1121
 None
 1.14A 2w98B-4ziuA:
undetectable		 2w98B-4ziuA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 LEU A1423
LEU A1386
LEU A1413
LEU A1431
ARG A1175
 None
 0.98A 2xn6A-4ziuA:
undetectable
2xn6B-4ziuA:
undetectable		 2xn6A-4ziuA:
20.31
2xn6B-4ziuA:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 10 LEU A1423
LEU A1386
LEU A1413
LEU A1431
ARG A1175
 None
 0.93A 2xn7A-4ziuA:
undetectable
2xn7B-4ziuA:
undetectable		 2xn7A-4ziuA:
20.00
2xn7B-4ziuA:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 5 LEU A1569
ILE A1511
ARG A1509
TRP A1533
 None
 1.43A 2zlcA-4ziuA:
undetectable		 2zlcA-4ziuA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 TRP A1252
ALA A1303
VAL A1308
 None
 0.98A 3l8lC-4ziuA:
undetectable
3l8lD-4ziuA:
undetectable		 3l8lC-4ziuA:
2.53
3l8lD-4ziuA:
2.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 GLN A1345
ARG A1387
GLN A1309
GLU A1249
 None
 1.41A 4azvA-4ziuA:
undetectable		 4azvA-4ziuA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 ILE A1227
LEU A1231
PHE A1240
GLY A1279
 None
 1.01A 4hc3A-4ziuA:
undetectable		 4hc3A-4ziuA:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 ALA A1417
GLU A1179
LEU A1423
LEU A1431
 None
 0.98A 4iomA-4ziuA:
undetectable		 4iomA-4ziuA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 LEU A1433
ALA A1434
LEU A1395
LEU A1344
LEU A1413
 None
 1.16A 4j24D-4ziuA:
undetectable		 4j24D-4ziuA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 LEU A1025
MET A1027
ASP A1068
 None
 0.72A 4j7xB-4ziuA:
undetectable		 4j7xB-4ziuA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		3 / 3 SER A1541
ALA A1603
VAL A1602
 None
 0.63A 4o2bA-4ziuA:
undetectable		 4o2bA-4ziuA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 7 SER A1424
ARG A1371
SER A1384
GLU A1427
 None
 1.27A 4xzkA-4ziuA:
undetectable		 4xzkA-4ziuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		5 / 12 LEU A1401
ALA A1313
GLY A1340
ALA A1366
LEU A1367
 None
 1.02A 5jw1B-4ziuA:
undetectable		 5jw1B-4ziuA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 ASP A1381
TYR A1311
SER A1428
SER A1339
 None
 1.13A 5l1fA-4ziuA:
undetectable
5l1fB-4ziuA:
undetectable		 5l1fA-4ziuA:
21.35
5l1fB-4ziuA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 8 LEU A1283
TYR A1286
GLU A1249
ASN A1237
 None
 1.24A 6c71B-4ziuA:
undetectable		 6c71B-4ziuA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM
(Escherichia
coli) 		4 / 6 TRP A1144
GLY A1167
ALA A1137
LEU A1486
 None
 1.05A 6fosA-4ziuA:
2.3		 6fosA-4ziuA:
8.78