SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zjp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		4 / 6 VAL A 267
GLY A 266
ALA A  46
LEU A  57
 None
 0.74A 1e7bB-4zjpA:
undetectable		 1e7bB-4zjpA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		4 / 5 ASP A 271
LEU A  85
ALA A  50
LEU A  53
 None
 1.09A 1nh8A-4zjpA:
undetectable		 1nh8A-4zjpA:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		5 / 12 THR A 239
ASP A 237
GLY A 235
ILE A 209
ALA A 223
 None
RIP  A 301 (-2.8A)
None
None
None
 1.38A 1oltA-4zjpA:
undetectable		 1oltA-4zjpA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		4 / 6 THR A 158
PHE A 187
PHE A  39
ASN A  87
 None
RIP  A 301 (-3.4A)
RIP  A 301 (-4.6A)
None
 1.49A 1tt0C-4zjpA:
undetectable		 1tt0C-4zjpA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		5 / 12 ILE A 172
GLY A 165
GLY A 132
ALA A 171
ALA A 160
 None
None
None
None
RIP  A 301 (-3.3A)
 1.07A 2yvlA-4zjpA:
4.9		 2yvlA-4zjpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		5 / 12 ILE A 172
GLY A 165
GLY A 132
ALA A 171
ALA A 160
 None
None
None
None
RIP  A 301 (-3.3A)
 1.08A 2yvlD-4zjpA:
undetectable		 2yvlD-4zjpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		4 / 7 LEU A 232
ALA A 253
THR A 291
VAL A 289
 None
 0.70A 3ozkB-4zjpA:
undetectable		 3ozkB-4zjpA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		5 / 12 PHE A 210
GLY A 132
GLY A 136
ALA A 171
GLY A 167
 None
 1.00A 3tegA-4zjpA:
undetectable		 3tegA-4zjpA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		4 / 8 THR A 269
ILE A 283
VAL A 285
GLY A 263
 None
 0.84A 4eq4B-4zjpA:
2.9		 4eq4B-4zjpA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		5 / 12 LEU A 221
LEU A 218
GLY A 219
LEU A 152
VAL A 234
 None
 1.37A 4olmA-4zjpA:
undetectable		 4olmA-4zjpA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4zjp MONOSACCHARIDE-TRANS
PORTING ATPASE
(Actinobacillus
succinogenes) 		5 / 12 LEU A 111
ILE A 262
ILE A 109
VAL A 120
ILE A 124
 None
 1.04A 6emuB-4zjpA:
4.8		 6emuB-4zjpA:
24.08