SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zk7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4zk7 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Thermus
thermophilus) 		4 / 6 PHE M  64
VAL M  57
LEU M  22
ALA M  63
 None
 0.98A 2e1qA-4zk7M:
undetectable		 2e1qA-4zk7M:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4zk7 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Thermus
thermophilus) 		4 / 6 PHE M  64
VAL M  57
LEU M  22
ALA M  63
 None
 0.97A 2e1qC-4zk7M:
undetectable		 2e1qC-4zk7M:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4zk7 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Thermus
thermophilus) 		4 / 6 LEU M  74
VAL M  71
VAL M  31
VAL M  57
 None
 0.98A 2z97A-4zk7M:
undetectable		 2z97A-4zk7M:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4zk7 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Thermus
thermophilus) 		4 / 7 PHE M  64
VAL M  57
LEU M  22
ALA M  63
 None
 1.00A 3uniA-4zk7M:
undetectable		 3uniA-4zk7M:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4zk7 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Thermus
thermophilus) 		4 / 4 LEU M  55
TYR M  41
PRO M  80
ILE M  82
 None
 0.99A 5esgA-4zk7M:
undetectable		 5esgA-4zk7M:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 4zk7 DIVALENT-CATION
TOLERANCE PROTEIN
CUTA
(Thermus
thermophilus) 		4 / 6 TYR M  77
VAL M  79
TYR M  41
GLU M  43
 None
 0.94A 5z3jA-4zk7M:
undetectable		 5z3jA-4zk7M:
15.85