SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zkq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_J_ZPCJ1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	4zkq	PUTATIVE UNCHARACTERIZED PROTEIN (Cricetid gammaherpesvirus 2)	4 / 5	GLU A 116 GLU A 115 PHE A 110 HIS A 253	None	1.08A	4a97J-4zkqA: undetectable	4a97J-4zkqA: 21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4USW_A_ACTA1470_0 (ADENYLATE CYCLASE TYPE 10)	4zkq	PUTATIVE UNCHARACTERIZED PROTEIN (Cricetid gammaherpesvirus 2)	4 / 6	LYS A 319 LEU A 318 LEU A 400 VAL A 399	None	1.06A	4uswA-4zkqA: undetectable	4uswA-4zkqA: 23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FUK_A_SNPA1236_1 (MROUPO)	4zkq	PUTATIVE UNCHARACTERIZED PROTEIN (Cricetid gammaherpesvirus 2)	4 / 7	ILE A 217 THR A 80 ILE A 79 LEU A 221	None	0.81A	5fukA-4zkqA: undetectable 5fukB-4zkqA: undetectable	5fukA-4zkqA: 18.52 5fukB-4zkqA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5SXQ_B_NIZB808_1 (CATALASE-PEROXIDASE)	4zkq	PUTATIVE UNCHARACTERIZED PROTEIN (Cricetid gammaherpesvirus 2)	4 / 8	GLU A 384 VAL A 308 GLY A 391 LEU A 381	None	1.06A	5sxqB-4zkqA: undetectable	5sxqB-4zkqA: 18.94

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A97_J_ZPCJ1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL","4zkq","PUTATIVE UNCHARACTERIZED PROTEIN","Cricetid gammaherpesvirus 2",4,"GLU A 116;GLU A 115;PHE A 110;HIS A 253","None","1.08A","4a97J-4zkqA:undetectable","4a97J-4zkqA:21.78"],["4USW_A_ACTA1470_0","ADENYLATE CYCLASE TYPE 10","4zkq","PUTATIVE UNCHARACTERIZED PROTEIN","Cricetid gammaherpesvirus 2",4,"LYS A 319;LEU A 318;LEU A 400;VAL A 399","None","1.06A","4uswA-4zkqA:undetectable","4uswA-4zkqA:23.09"],["5FUK_A_SNPA1236_1","MROUPO;MROUPO","4zkq","PUTATIVE UNCHARACTERIZED PROTEIN","Cricetid gammaherpesvirus 2",4,"ILE A 217;THR A  80;ILE A  79;LEU A 221","None","0.81A","5fukA-4zkqA:undetectable;5fukB-4zkqA:undetectable","5fukA-4zkqA:18.52;5fukB-4zkqA:18.52"],["5SXQ_B_NIZB808_1","CATALASE-PEROXIDASE","4zkq","PUTATIVE UNCHARACTERIZED PROTEIN","Cricetid gammaherpesvirus 2",4,"GLU A 384;VAL A 308;GLY A 391;LEU A 381","None","1.06A","5sxqB-4zkqA:undetectable","5sxqB-4zkqA:18.94"]]