SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zlg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		3 / 3 GLN A 377
HIS A 445
PRO A 432
 None
 0.91A 1d8cA-4zlgA:
undetectable		 1d8cA-4zlgA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 GLN A 332
THR A 694
ASN A 340
GLY A 308
VAL A 697
 None
SO4  A 805 (-3.7A)
None
None
None
 0.96A 1jg4A-4zlgA:
undetectable		 1jg4A-4zlgA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 4 SER A 634
LEU A 580
TYR A 631
GLY A 639
 None
 1.41A 1liiA-4zlgA:
undetectable		 1liiA-4zlgA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		3 / 3 LEU A 418
LEU A 498
MET A 446
 None
 0.77A 1ya3B-4zlgA:
undetectable		 1ya3B-4zlgA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 ALA A 644
ILE A 632
VAL A 708
PHE A 709
LEU A 312
 None
 1.27A 2h42A-4zlgA:
undetectable		 2h42A-4zlgA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 7 TYR A  40
TYR A  81
GLU A 224
GLY A 228
 None
 1.26A 2ha4B-4zlgA:
undetectable		 2ha4B-4zlgA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 6 LEU A 142
ASN A 104
ILE A  82
PHE A  80
 None
SO4  A 806 (-3.1A)
None
None
 0.95A 2jn3A-4zlgA:
0.8		 2jn3A-4zlgA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		3 / 3 ARG A 349
ASP A 345
ASN A 350
 LGC  A 804 (-4.0A)
GOL  A 802 (-3.0A)
LGC  A 804 (-3.0A)
 0.76A 2zzmA-4zlgA:
undetectable		 2zzmA-4zlgA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 VAL A 484
ASP A 458
ARG A 457
ILE A 522
THR A 492
 None
 1.30A 3bexC-4zlgA:
undetectable
3bexD-4zlgA:
undetectable		 3bexC-4zlgA:
14.32
3bexD-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 10 THR A 492
VAL A 484
ASP A 458
ARG A 457
ILE A 522
 None
 1.31A 3bexC-4zlgA:
undetectable
3bexD-4zlgA:
undetectable		 3bexC-4zlgA:
14.32
3bexD-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 10 VAL A 484
ASP A 458
ARG A 457
ILE A 522
THR A 492
 None
 1.30A 3bexE-4zlgA:
undetectable
3bexF-4zlgA:
undetectable		 3bexE-4zlgA:
14.32
3bexF-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 THR A 492
VAL A 484
ASP A 458
ARG A 457
ILE A 522
 None
 1.30A 3bexE-4zlgA:
undetectable
3bexF-4zlgA:
undetectable		 3bexE-4zlgA:
14.32
3bexF-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 VAL A 484
ASP A 458
ARG A 457
ILE A 522
THR A 492
 None
 1.34A 3bf1A-4zlgA:
undetectable
3bf1B-4zlgA:
undetectable		 3bf1A-4zlgA:
14.32
3bf1B-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 VAL A 484
ASP A 458
ARG A 457
ILE A 522
THR A 492
 None
 1.32A 3bf1C-4zlgA:
undetectable
3bf1D-4zlgA:
undetectable		 3bf1C-4zlgA:
14.32
3bf1D-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 THR A 492
VAL A 484
ASP A 458
ARG A 457
ILE A 522
 None
 1.34A 3bf1C-4zlgA:
undetectable
3bf1D-4zlgA:
undetectable		 3bf1C-4zlgA:
14.32
3bf1D-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 VAL A 484
ASP A 458
ARG A 457
ILE A 522
THR A 492
 None
 1.30A 3bf1E-4zlgA:
undetectable
3bf1F-4zlgA:
undetectable		 3bf1E-4zlgA:
14.32
3bf1F-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 THR A 492
VAL A 484
ASP A 458
ARG A 457
ILE A 522
 None
 1.32A 3bf1E-4zlgA:
undetectable
3bf1F-4zlgA:
undetectable		 3bf1E-4zlgA:
14.32
3bf1F-4zlgA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		3 / 3 LYS A 551
ILE A 465
PHE A 464
 None
 0.75A 3j7zS-4zlgA:
1.0
3j7za-4zlgA:
undetectable		 3j7zS-4zlgA:
9.91
3j7za-4zlgA:
2.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		3 / 3 HIS A 406
SER A 380
GLU A 378
 None
 0.77A 3s8pA-4zlgA:
undetectable		 3s8pA-4zlgA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		3 / 3 GLN A 265
GLU A 141
LYS A 143
 None
 1.22A 3su9A-4zlgA:
undetectable		 3su9A-4zlgA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 8 LEU A 546
ARG A 538
VAL A 484
LEU A 462
 None
CL  A 807 (-4.0A)
None
None
 0.90A 3uniB-4zlgA:
undetectable		 3uniB-4zlgA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 8 ARG A 341
VAL A 697
VAL A 700
GLN A 332
 SO4  A 805 (-3.0A)
None
None
None
 0.99A 3uy4A-4zlgA:
undetectable		 3uy4A-4zlgA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 4 ASP A 469
THR A 404
VAL A 477
SER A 463
 None
 1.17A 3wxoA-4zlgA:
undetectable		 3wxoA-4zlgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 6 GLY A 147
GLY A 148
GLU A 124
ILE A 123
 None
 0.97A 4fglD-4zlgA:
undetectable		 4fglD-4zlgA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 6 GLU A 619
ASP A 472
ASP A 469
ARG A 349
 LGC  A 804 ( 3.7A)
LGC  A 804 ( 4.0A)
None
LGC  A 804 (-4.0A)
 1.36A 4kcnA-4zlgA:
undetectable		 4kcnA-4zlgA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 4 LEU A   2
SER A  15
LEU A 661
LEU A 666
 GOL  A 803 ( 4.1A)
GOL  A 803 ( 4.6A)
None
None
 0.92A 4n09A-4zlgA:
undetectable		 4n09A-4zlgA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 VAL A 484
ASP A 458
ARG A 457
ILE A 522
THR A 492
 None
 1.25A 4o5fA-4zlgA:
undetectable
4o5fB-4zlgA:
undetectable		 4o5fA-4zlgA:
16.08
4o5fB-4zlgA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 THR A 492
VAL A 484
ASP A 458
ARG A 457
ILE A 522
 None
 1.28A 4o5fA-4zlgA:
undetectable
4o5fB-4zlgA:
undetectable		 4o5fA-4zlgA:
16.08
4o5fB-4zlgA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 LEU A 102
GLU A  96
PRO A  16
THR A  17
ARG A  38
 None
 1.35A 4q15A-4zlgA:
undetectable		 4q15A-4zlgA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		6 / 12 GLY A 568
LEU A 488
ILE A 566
SER A 563
ILE A 522
ALA A 570
 None
 1.38A 4qtuB-4zlgA:
undetectable		 4qtuB-4zlgA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 5 ILE A   5
PHE A  25
SER A 106
ASP A 113
 None
None
SO4  A 806 (-2.6A)
None
 0.97A 4rzvB-4zlgA:
undetectable		 4rzvB-4zlgA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 GLU A 573
ILE A 576
GLN A 562
ILE A 566
SER A 637
 None
 1.16A 4uroC-4zlgA:
undetectable		 4uroC-4zlgA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 7 TYR A  71
TRP A 116
ILE A 114
HIS A  75
 None
 1.23A 4xo7B-4zlgA:
undetectable		 4xo7B-4zlgA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 10 ALA A 685
TYR A 673
SER A 617
SER A 622
GLY A 676
 None
 1.23A 4xp1A-4zlgA:
undetectable		 4xp1A-4zlgA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 VAL A 484
ASP A 458
ARG A 457
ILE A 522
THR A 492
 None
 1.28A 5b8hA-4zlgA:
undetectable
5b8hB-4zlgA:
undetectable		 5b8hA-4zlgA:
17.03
5b8hB-4zlgA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 THR A 492
VAL A 484
ASP A 458
ARG A 457
ILE A 522
 None
 1.27A 5b8hA-4zlgA:
undetectable
5b8hB-4zlgA:
undetectable		 5b8hA-4zlgA:
17.03
5b8hB-4zlgA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB403_0
(D-ALANINE--D-ALANINE
LIGASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 5 TYR A 624
ARG A 341
ASN A 350
GLY A 695
 SO4  A 805 ( 4.7A)
SO4  A 805 (-3.0A)
LGC  A 804 (-3.0A)
SO4  A 805 (-3.8A)
 1.33A 5bphB-4zlgA:
0.0		 5bphB-4zlgA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 PHE A 633
ARG A 702
TYR A 701
ILE A 705
LEU A 321
 None
 1.17A 5ljbA-4zlgA:
2.6		 5ljbA-4zlgA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 12 PHE A 633
ARG A 702
TYR A 701
ILE A 705
LEU A 321
 None
 1.16A 5ljcA-4zlgA:
undetectable		 5ljcA-4zlgA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 7 TYR A 360
ILE A 361
THR A 366
ILE A 365
 None
 0.91A 5murB-4zlgA:
2.7		 5murB-4zlgA:
6.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 8 LEU A 427
VAL A 442
MET A 414
TYR A 417
 None
 1.02A 5nu7A-4zlgA:
undetectable		 5nu7A-4zlgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 7 THR A 694
LEU A 648
LYS A 646
GLU A 320
 SO4  A 805 (-3.7A)
None
None
None
 1.13A 5tudA-4zlgA:
2.2		 5tudA-4zlgA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 9 LEU A 154
SER A 155
ILE A 144
VAL A 125
ILE A  82
 None
 1.27A 6ef6A-4zlgA:
undetectable		 6ef6A-4zlgA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 7 ASP A 469
GLY A 537
SER A 485
GLY A 486
 None
 0.97A 6ekzA-4zlgA:
undetectable		 6ekzA-4zlgA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 5 ALA A 234
TYR A 157
GLN A 236
ILE A  90
 None
 1.21A 6f6sA-4zlgA:
undetectable
6f6sB-4zlgA:
0.0		 6f6sA-4zlgA:
8.36
6f6sB-4zlgA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		4 / 8 LYS A 480
LYS A 482
GLY A 483
GLY A 544
 None
 0.75A 6mdqA-4zlgA:
undetectable		 6mdqA-4zlgA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE
(Saccharophagus
degradans) 		5 / 11 SER A 463
LEU A 453
ALA A 495
TRP A 487
ALA A 491
 None
 1.38A 6qgbE-4zlgA:
undetectable		 6qgbE-4zlgA:
21.89