SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zlh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 4zlh LIPOPOLYSACCHARIDE
ASSEMBLY PROTEIN B
(Escherichia
coli) 		4 / 8 LEU A 133
GLU A 136
THR A 102
ILE A 110
 None
 1.03A 1qvtA-4zlhA:
undetectable		 1qvtA-4zlhA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4zlh LIPOPOLYSACCHARIDE
ASSEMBLY PROTEIN B
(Escherichia
coli) 		4 / 7 SER A 155
TRP A 157
PHE A 182
GLU A 156
 None
 1.42A 3n5tA-4zlhA:
undetectable
3n5tB-4zlhA:
undetectable		 3n5tA-4zlhA:
20.65
3n5tB-4zlhA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 4zlh LIPOPOLYSACCHARIDE
ASSEMBLY PROTEIN B
(Escherichia
coli) 		3 / 3 LEU A 113
ASP A 116
TYR A 117
 None
 0.54A 4qc6B-4zlhA:
undetectable		 4qc6B-4zlhA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 4zlh LIPOPOLYSACCHARIDE
ASSEMBLY PROTEIN B
(Escherichia
coli) 		4 / 5 ILE A 305
ILE A 292
TYR A 324
GLU A 293
 None
 1.22A 4zzcE-4zlhA:
3.0		 4zzcE-4zlhA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 4zlh LIPOPOLYSACCHARIDE
ASSEMBLY PROTEIN B
(Escherichia
coli) 		3 / 3 HIS A 181
GLU A 185
TRP A 369
 None
 1.24A 5odiD-4zlhA:
undetectable		 5odiD-4zlhA:
17.99