SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ARG A 245
LEU A 169
LEU A  78
ASP A  81
MET A  82
 None
 1.29A 1e7wA-4zmhA:
undetectable		 1e7wA-4zmhA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ARG A 245
LEU A 192
LEU A 169
LEU A  78
ASP A  81
 None
 1.18A 1e7wA-4zmhA:
undetectable		 1e7wA-4zmhA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.01A 1fkfA-4zmhA:
undetectable		 1fkfA-4zmhA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.00A 1fkjA-4zmhA:
undetectable		 1fkjA-4zmhA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.07A 1fklA-4zmhA:
undetectable		 1fklA-4zmhA:
7.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 SER A 108
VAL A 109
GLY A 110
TYR A  68
GLY A 156
 None
 1.42A 1iolA-4zmhA:
undetectable		 1iolA-4zmhA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ALA A 894
VAL A 940
TRP A 952
 None
 0.88A 1micA-4zmhA:
undetectable
1micB-4zmhA:
undetectable		 1micA-4zmhA:
2.77
1micB-4zmhA:
2.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ASP A 403
THR A 880
GLU A 451
 None
 0.85A 1pj7A-4zmhA:
4.3		 1pj7A-4zmhA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ILE A 954
GLY A 965
VAL A 871
ALA A 800
LEU A 865
 None
 0.72A 1vptA-4zmhA:
undetectable		 1vptA-4zmhA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ALA A  74
GLY A 165
ILE A 163
ASP A 128
ILE A 129
 None
None
None
PO4  A1002 ( 4.7A)
None
 0.97A 1x1aA-4zmhA:
undetectable		 1x1aA-4zmhA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.17A 1yatA-4zmhA:
undetectable		 1yatA-4zmhA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.02A 2fkeA-4zmhA:
undetectable		 2fkeA-4zmhA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 LYS A 380
GLY A 434
PRO A 435
 ACT  A1007 ( 3.6A)
GOL  A1006 ( 2.9A)
None
 0.89A 2hreB-4zmhA:
undetectable		 2hreB-4zmhA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ARG A 924
GLY A 965
PRO A 966
 None
 0.49A 2hreD-4zmhA:
undetectable		 2hreD-4zmhA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 6 LEU A 124
ILE A 129
VAL A 109
ALA A 155
 None
 1.04A 2j5mA-4zmhA:
undetectable		 2j5mA-4zmhA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 7 GLN A 580
TYR A 634
TYR A 579
TYR A 524
 None
 1.27A 2ph9A-4zmhA:
undetectable
2ph9B-4zmhA:
undetectable		 2ph9A-4zmhA:
14.88
2ph9B-4zmhA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 TRP A 180
VAL A 184
TRP A 181
 None
 1.33A 2xdcE-4zmhA:
undetectable
2xdcF-4zmhA:
undetectable		 2xdcE-4zmhA:
2.77
2xdcF-4zmhA:
2.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 4 LEU A 964
GLN A 526
THR A 831
THR A 540
 None
 1.43A 2zj0D-4zmhA:
undetectable		 2zj0D-4zmhA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 TRP A 312
VAL A 382
ARG A 410
 None
 0.89A 3b0wA-4zmhA:
undetectable		 3b0wA-4zmhA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 10 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.14A 3ihzA-4zmhA:
undetectable		 3ihzA-4zmhA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 7 PHE A 877
SER A 926
VAL A 873
VAL A 903
 None
 1.20A 3n61A-4zmhA:
undetectable
3n61B-4zmhA:
undetectable		 3n61A-4zmhA:
17.51
3n61B-4zmhA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 8 PHE A 877
SER A 926
VAL A 873
VAL A 903
 None
 1.18A 3nlrA-4zmhA:
undetectable
3nlrB-4zmhA:
undetectable		 3nlrA-4zmhA:
17.51
3nlrB-4zmhA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 6 GLU A 824
THR A 948
ALA A 809
ALA A 808
 None
 1.24A 3ns1C-4zmhA:
undetectable		 3ns1C-4zmhA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 7 PHE A 624
ASP A 661
VAL A 592
TYR A 596
 None
 0.86A 3p6hA-4zmhA:
undetectable		 3p6hA-4zmhA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 LYS A 951
ARG A 551
LEU A 964
 None
 1.36A 3v4tE-4zmhA:
undetectable		 3v4tE-4zmhA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ARG A 417
 None
 1.00A 3vawA-4zmhA:
undetectable		 3vawA-4zmhA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.05A 3vawA-4zmhA:
undetectable		 3vawA-4zmhA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 8 TRP A 914
ARG A 923
GLU A 916
HIS A 911
 GOL  A1005 ( 4.8A)
None
None
GOL  A1005 ( 4.8A)
 1.26A 3zmdA-4zmhA:
undetectable
3zmdB-4zmhA:
undetectable		 3zmdA-4zmhA:
9.58
3zmdB-4zmhA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 TRP A 881
VAL A 922
TRP A 914
 None
None
GOL  A1005 ( 4.8A)
 1.28A 3zq8A-4zmhA:
undetectable
3zq8B-4zmhA:
undetectable		 3zq8A-4zmhA:
2.77
3zq8B-4zmhA:
2.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 5 ILE A 358
GLN A 374
ILE A 325
GLU A 323
 None
 0.90A 4a99D-4zmhA:
3.8		 4a99D-4zmhA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.19A 4drhA-4zmhA:
undetectable		 4drhA-4zmhA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.08A 4dz2A-4zmhA:
undetectable
4dz2B-4zmhA:
undetectable		 4dz2A-4zmhA:
8.63
4dz2B-4zmhA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.10A 4dz2A-4zmhA:
undetectable
4dz2B-4zmhA:
undetectable		 4dz2A-4zmhA:
8.63
4dz2B-4zmhA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 10 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.11A 4dz3A-4zmhA:
undetectable		 4dz3A-4zmhA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 10 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.11A 4dz3B-4zmhA:
undetectable		 4dz3B-4zmhA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ARG A 919
TRP A 405
GLY A 434
 None
None
GOL  A1006 ( 2.9A)
 0.90A 4e7cA-4zmhA:
undetectable		 4e7cA-4zmhA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		4 / 7 ARG A 531
SER A 910
VAL A 918
TRP A 914
 None
None
None
GOL  A1005 ( 4.8A)
 1.48A 4klaA-4zmhA:
undetectable		 4klaA-4zmhA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 10 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.10A 4laxA-4zmhA:
undetectable		 4laxA-4zmhA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 TYR A 653
ARG A 439
SER A 437
 None
 1.21A 4lf7I-4zmhA:
undetectable
4lf7J-4zmhA:
undetectable		 4lf7I-4zmhA:
8.74
4lf7J-4zmhA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 TYR A 653
ARG A 439
SER A 437
 None
 1.21A 4lf8I-4zmhA:
undetectable
4lf8J-4zmhA:
undetectable		 4lf8I-4zmhA:
8.74
4lf8J-4zmhA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 10 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.21A 4nnrB-4zmhA:
undetectable		 4nnrB-4zmhA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 PRO A 412
LEU A 411
HIS A 454
 None
 0.66A 4pevA-4zmhA:
3.2		 4pevA-4zmhA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ARG A 209
GLN A 207
GLU A 134
 None
 0.81A 4tvtA-4zmhA:
2.4		 4tvtA-4zmhA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHQ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 VAL A 269
TYR A 322
ASN A 249
ARG A 245
ASP A  77
 None
 1.43A 5fhqA-4zmhA:
undetectable		 5fhqA-4zmhA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 TRP A 487
GLU A 484
ASP A 168
 None
 1.03A 5gqbA-4zmhA:
4.2		 5gqbA-4zmhA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 11 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.13A 5hw8D-4zmhA:
undetectable		 5hw8D-4zmhA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 GLY A 470
ASP A 471
ASN A 222
 None
NA  A1004 (-3.0A)
None
 0.43A 5jglA-4zmhA:
undetectable		 5jglA-4zmhA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ALA A 925
GLY A 934
THR A 932
HIS A 929
THR A 872
 None
 1.24A 5jlcA-4zmhA:
1.0		 5jlcA-4zmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 LEU A 721
VAL A 680
SER A 724
ILE A 748
GLU A 745
 None
 1.49A 5w8aA-4zmhA:
undetectable		 5w8aA-4zmhA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 LYS A 951
LEU A 876
ARG A 830
 None
 0.93A 5yw0A-4zmhA:
undetectable		 5yw0A-4zmhA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 ARG A 355
ARG A 419
ARG A 391
 None
 0.81A 6bplA-4zmhA:
3.0
6bplB-4zmhA:
undetectable		 6bplA-4zmhA:
6.44
6bplB-4zmhA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 LEU A 399
HIS A 282
ASP A 402
ASN A 404
HIS A 428
 None
None
None
ACT  A1007 (-3.6A)
PO4  A1001 (-3.9A)
 1.39A 6exiC-4zmhA:
undetectable		 6exiC-4zmhA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		5 / 12 ASP A 944
PHE A 845
ILE A 840
TYR A 459
ILE A 883
 None
 1.03A 6mkeA-4zmhA:
undetectable
6mkeD-4zmhA:
undetectable		 6mkeA-4zmhA:
6.27
6mkeD-4zmhA:
6.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4zmh UNCHARACTERIZED
PROTEIN
(Saccharophagus
degradans) 		3 / 3 THR A 525
GLU A 534
ASN A 442
 None
 0.85A 6nj9K-4zmhA:
undetectable		 6nj9K-4zmhA:
19.47