SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 12 PHE A 340
PHE A 230
LEU A 184
VAL A 181
VAL A 155
 None
 1.33A 1q23B-4zmiA:
undetectable		 1q23B-4zmiA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 9 LEU A 254
LEU A 251
ILE A 293
PHE A 271
ILE A 318
 None
 1.17A 2f7aA-4zmiA:
undetectable		 2f7aA-4zmiA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 9 LEU A 254
LEU A 251
ILE A 293
PHE A 271
ILE A 318
 None
 1.25A 2f7aB-4zmiA:
undetectable		 2f7aB-4zmiA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 11 LEU A 251
LEU A 254
ILE A 326
ASN A 328
LEU A 246
 None
 1.13A 2ft9A-4zmiA:
undetectable		 2ft9A-4zmiA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 224
LEU A 191
LEU A 197
GLY A 196
PHE A 217
 None
 1.20A 3g1uA-4zmiA:
undetectable		 3g1uA-4zmiA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 224
LEU A 191
LEU A 197
GLY A 196
PHE A 217
 None
 1.21A 3g1uB-4zmiA:
undetectable		 3g1uB-4zmiA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 224
LEU A 191
LEU A 197
GLY A 196
PHE A 217
 None
 1.25A 3g1uC-4zmiA:
undetectable		 3g1uC-4zmiA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 224
LEU A 191
LEU A 197
GLY A 196
PHE A 217
 None
 1.19A 3g1uD-4zmiA:
undetectable		 3g1uD-4zmiA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 224
LEU A 191
LEU A 197
GLY A 196
PHE A 217
 None
 1.22A 3glqA-4zmiA:
undetectable		 3glqA-4zmiA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 224
LEU A 191
LEU A 197
GLY A 196
PHE A 217
 None
 1.25A 3glqB-4zmiA:
undetectable		 3glqB-4zmiA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 224
LEU A 191
LEU A 197
GLY A 196
PHE A 217
 None
 1.23A 3n58A-4zmiA:
undetectable		 3n58A-4zmiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		5 / 9 LEU A 237
PHE A 172
ILE A 166
GLY A 177
LYS A 178
 None
 1.43A 3oshA-4zmiA:
undetectable		 3oshA-4zmiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		3 / 3 ARG A 247
LEU A 251
THR A 201
 None
 0.90A 3oxcA-4zmiA:
undetectable		 3oxcA-4zmiA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		4 / 7 ALA A 267
TYR A 264
ALA A 257
ARG A 359
 None
 0.95A 3twpB-4zmiA:
undetectable		 3twpB-4zmiA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		4 / 8 SER A 171
ARG A 277
ILE A 166
GLU A 170
 None
 1.25A 4cx7A-4zmiA:
undetectable
4cx7B-4zmiA:
undetectable		 4cx7A-4zmiA:
19.55
4cx7B-4zmiA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		4 / 8 SER A 171
ARG A 277
ILE A 166
GLU A 170
 None
 1.27A 4cx7C-4zmiA:
undetectable
4cx7D-4zmiA:
undetectable		 4cx7C-4zmiA:
19.55
4cx7D-4zmiA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4zmi TELOMERE LENGTH
REGULATOR TAZ1
(Schizosaccharomy
ces
pombe) 		4 / 7 ASN A 168
TYR A 278
LEU A 274
PHE A 271
 None
 1.23A 4yv5A-4zmiA:
undetectable		 4yv5A-4zmiA:
17.45