SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		4 / 7 MET A 284
PRO A 157
ALA A 291
ALA A 132
 None
EDO  A 503 (-4.5A)
None
None
 0.97A 1k5qA-4zn6A:
undetectable
1k5qB-4zn6A:
2.4		 1k5qA-4zn6A:
20.79
1k5qB-4zn6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		4 / 7 TYR A 173
GLU A 239
SER A 266
VAL A 268
 None
SO4  A 501 ( 4.5A)
None
None
 1.23A 1tv8B-4zn6A:
undetectable		 1tv8B-4zn6A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		4 / 8 LEU A 137
SER A 140
ALA A 148
ALA A 147
 None
 0.91A 3ax9B-4zn6A:
undetectable		 3ax9B-4zn6A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		6 / 10 LEU A  16
ALA A 114
VAL A 111
ILE A 383
ALA A 108
ILE A 110
 None
 1.49A 3ekpB-4zn6A:
undetectable		 3ekpB-4zn6A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		4 / 7 GLY A  17
GLY A  20
THR A  26
ALA A 109
 None
 0.85A 3fpjB-4zn6A:
4.3		 3fpjB-4zn6A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		3 / 3 ARG A  47
ILE A  15
THR A 119
 None
 0.67A 3ia4D-4zn6A:
undetectable		 3ia4D-4zn6A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		5 / 11 GLN A  11
VAL A 158
ALA A 132
THR A  26
ILE A  22
 None
 1.35A 3n23A-4zn6A:
undetectable		 3n23A-4zn6A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 120
PRO A 118
GLN A  91
ASP A 390
GLY A 112
 None
 1.37A 4j7xF-4zn6A:
6.7		 4j7xF-4zn6A:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A  54
VAL A  63
VAL A  65
GLY A 115
THR A 119
 None
 1.25A 5igiA-4zn6A:
0.6		 5igiA-4zn6A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		3 / 3 LEU A 131
LEU A 156
TRP A 294
 EDO  A 503 (-4.4A)
None
None
 0.87A 5nwuA-4zn6A:
undetectable		 5nwuA-4zn6A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zn6 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE
(Acinetobacter
baumannii) 		4 / 6 LYS A 188
GLN A 269
LEU A 169
PHE A 247
 None
 1.33A 6nmpC-4zn6A:
undetectable
6nmpJ-4zn6A:
undetectable		 6nmpC-4zn6A:
21.07
6nmpJ-4zn6A:
12.00