SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4znj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 5 ARG A 170
ALA A 141
ASP A 144
GLY A  63
 None
 1.06A 1e7bA-4znjA:
undetectable		 1e7bA-4znjA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHO_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 9 GLY A 201
GLY A 182
PHE A 252
LEU A 183
ARG A 245
 None
 1.17A 1jhoA-4znjA:
undetectable		 1jhoA-4znjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHR_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 9 GLY A 201
GLY A 182
PHE A 252
LEU A 183
ARG A 245
 None
 1.19A 1jhrA-4znjA:
undetectable		 1jhrA-4znjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHY_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 9 GLY A 201
GLY A 182
PHE A 252
LEU A 183
ARG A 245
 None
 1.21A 1jhyA-4znjA:
undetectable		 1jhyA-4znjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 9 GLY A 201
GLY A 182
PHE A 252
LEU A 183
ARG A 245
 None
 1.24A 1l4nA-4znjA:
undetectable		 1l4nA-4znjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5K_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 9 GLY A 201
GLY A 182
PHE A 252
LEU A 183
ARG A 245
 None
 1.19A 1l5kA-4znjA:
undetectable		 1l5kA-4znjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5L_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 9 GLY A 201
GLY A 182
PHE A 252
LEU A 183
ARG A 245
 None
 1.18A 1l5lA-4znjA:
undetectable		 1l5lA-4znjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5M_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 9 GLY A 201
GLY A 182
PHE A 252
LEU A 183
ARG A 245
 None
 1.19A 1l5mA-4znjA:
undetectable		 1l5mA-4znjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 12 ARG A  32
ILE A 176
PHE A 189
THR A 166
LEU A 143
 None
 0.95A 1og5B-4znjA:
undetectable		 1og5B-4znjA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 5 ILE A 154
PRO A 155
PHE A 156
ILE A 176
 None
 1.04A 2hjhA-4znjA:
undetectable		 2hjhA-4znjA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 5 VAL A 158
PHE A 189
ILE A 176
PHE A 214
 None
 1.11A 3owxB-4znjA:
undetectable		 3owxB-4znjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 8 TYR A  16
HIS A  26
LEU A 175
TRP A 173
 None
 1.11A 3uzzB-4znjA:
undetectable		 3uzzB-4znjA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 9 LEU A  87
ILE A  25
LEU A 175
ILE A 147
ILE A  76
 None
 1.23A 3zosB-4znjA:
undetectable		 3zosB-4znjA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MFL_B_GCSB502_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24
TEICOPLANIN
PSEUDOAGLYCONE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 6 TRP A 185
TRP A 159
ALA A 174
PHE A 214
 None
 1.44A 4mflA-4znjA:
0.0		 4mflA-4znjA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		5 / 12 ALA A  46
GLU A  50
LEU A 175
ARG A   5
LEU A  37
 None
 1.25A 4xi3D-4znjA:
undetectable		 4xi3D-4znjA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 5 GLY A 129
ARG A 128
GLY A  63
GLU A 126
 None
SO4  A 305 (-3.3A)
None
None
 1.28A 4z2eB-4znjA:
undetectable
4z2eC-4znjA:
undetectable		 4z2eB-4znjA:
21.03
4z2eC-4znjA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 7 GLY A 201
PHE A 252
SER A 205
ARG A 236
 None
 0.96A 5n5dB-4znjA:
4.8		 5n5dB-4znjA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4znj PHAGE TERMINASE
LARGE SUBUNIT
(Thermus
virus
P74-26) 		4 / 5 ARG A  86
LEU A  87
PHE A  10
LEU A  14
 None
 0.83A 5x1bP-4znjA:
undetectable		 5x1bP-4znjA:
18.93