SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		5 / 12 CYH A 179
ALA A 178
GLU A 184
LEU A 188
PHE A  79
 None
 1.28A 1s9pB-4zo0A:
undetectable		 1s9pB-4zo0A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 ILE A   9
ARG A 119
THR A  65
LEU A  64
 None
 0.92A 2einN-4zo0A:
undetectable
2einW-4zo0A:
undetectable		 2einN-4zo0A:
16.50
2einW-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 LEU A  37
PRO A  38
ARG A 185
 None
 0.64A 2qd4B-4zo0A:
undetectable		 2qd4B-4zo0A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 ILE A   9
PHE A 132
ARG A 119
THR A  65
 None
 0.76A 2zxwN-4zo0A:
undetectable
2zxwW-4zo0A:
undetectable		 2zxwN-4zo0A:
16.50
2zxwW-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 ILE A   9
PHE A 132
ARG A 119
THR A  65
 None
 0.82A 3ablN-4zo0A:
undetectable
3ablW-4zo0A:
undetectable		 3ablN-4zo0A:
16.50
3ablW-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 ILE A   9
ARG A 119
THR A  65
LEU A  64
 None
 0.93A 3ag1N-4zo0A:
undetectable
3ag1W-4zo0A:
undetectable		 3ag1N-4zo0A:
16.50
3ag1W-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 ILE A   9
PHE A 132
ARG A 119
THR A  65
 None
 0.73A 3ag3N-4zo0A:
undetectable
3ag3W-4zo0A:
undetectable		 3ag3N-4zo0A:
16.50
3ag3W-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 ILE A   9
PHE A 132
ARG A 119
THR A  65
 None
 0.87A 3ag4N-4zo0A:
undetectable
3ag4W-4zo0A:
undetectable		 3ag4N-4zo0A:
16.50
3ag4W-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 ILE A   7
LEU A 109
PHE A 132
THR A  65
 None
 1.04A 5b1aN-4zo0A:
undetectable
5b1aW-4zo0A:
undetectable		 5b1aN-4zo0A:
16.50
5b1aW-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 ILE A   9
PHE A 132
ARG A 119
THR A  65
 None
 0.80A 5iy5N-4zo0A:
undetectable
5iy5W-4zo0A:
undetectable		 5iy5N-4zo0A:
16.50
5iy5W-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 4 LEU A  45
ASP A  44
GLN A 162
VAL A  27
 None
 1.19A 6bzoF-4zo0A:
undetectable		 6bzoF-4zo0A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 ILE A   9
ARG A 119
THR A  65
LEU A  64
 None
 0.92A 6nmfA-4zo0A:
undetectable
6nmfJ-4zo0A:
undetectable		 6nmfA-4zo0A:
16.50
6nmfJ-4zo0A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4zo0 PROTEIN REP68
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 ILE A   9
ARG A 119
THR A  65
LEU A  64
 None
 0.90A 6nmpA-4zo0A:
undetectable
6nmpJ-4zo0A:
undetectable		 6nmpA-4zo0A:
16.50
6nmpJ-4zo0A:
17.78