SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zoq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 8 THR I 375
ASN I 275
ASP I 423
GLY I 277
 None
 0.98A 1bu5B-4zoqI:
2.5		 1bu5B-4zoqI:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 11 MET I 193
GLY I 192
THR I 348
GLY I 185
GLN I 189
 None
 1.37A 1jr1A-4zoqI:
undetectable		 1jr1A-4zoqI:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 6 LEU I 377
VAL I 389
ILE I 197
ARG I 411
 None
 1.03A 1opjB-4zoqI:
undetectable		 1opjB-4zoqI:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 ILE I 196
ALA I 383
ASN I 235
VAL I 346
SER I 237
 None
 1.32A 2gl0A-4zoqI:
undetectable
2gl0C-4zoqI:
undetectable		 2gl0A-4zoqI:
18.70
2gl0C-4zoqI:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 SER I 237
ILE I 196
ALA I 383
ASN I 235
VAL I 346
 None
 1.38A 2gl0D-4zoqI:
undetectable
2gl0E-4zoqI:
undetectable		 2gl0D-4zoqI:
18.70
2gl0E-4zoqI:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 11 THR I 204
SER I 376
LEU I 209
VAL I 208
ALA I 226
 None
 1.23A 2zbzA-4zoqI:
undetectable		 2zbzA-4zoqI:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 9 ARG I 319
ALA I 273
GLY I 277
VAL I 424
ILE I 321
 None
 1.20A 3em4B-4zoqI:
undetectable		 3em4B-4zoqI:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 5 LEU I 437
GLN I 137
THR I 135
GLU I 392
 None
 1.37A 3n58C-4zoqI:
2.9		 3n58C-4zoqI:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 11 ARG I 319
ALA I 273
GLY I 277
VAL I 424
ILE I 321
 None
 1.00A 3oxxD-4zoqI:
undetectable		 3oxxD-4zoqI:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 GLY I 318
GLU I 320
GLY I 277
ASP I 335
ASN I 279
 None
 1.27A 3qowA-4zoqI:
undetectable		 3qowA-4zoqI:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 GLU I 232
ILE I 390
SER I 391
GLU I 139
GLU I 395
 None
 1.29A 3r75A-4zoqI:
undetectable		 3r75A-4zoqI:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 ARG I 319
ALA I 273
GLY I 277
VAL I 424
ILE I 321
 None
 0.96A 3tkgB-4zoqI:
undetectable		 3tkgB-4zoqI:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 LEU I 123
LEU I 330
LEU I 377
GLY I 327
PHE I 125
 None
 0.94A 3uwlB-4zoqI:
undetectable		 3uwlB-4zoqI:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 LEU I 123
LEU I 330
LEU I 377
GLY I 327
PHE I 125
 None
 0.95A 3uwlD-4zoqI:
undetectable		 3uwlD-4zoqI:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 11 GLY I 274
ALA I 273
ILE I 321
ILE I 425
ILE I 311
 None
 1.02A 4dt8A-4zoqI:
undetectable		 4dt8A-4zoqI:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 10 GLY I 274
ALA I 273
ILE I 321
ILE I 425
ILE I 311
 None
 1.10A 4dt8B-4zoqI:
undetectable		 4dt8B-4zoqI:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		3 / 3 LYS I 128
TYR I 434
ARG I 432
 None
 1.34A 4gc9A-4zoqI:
undetectable		 4gc9A-4zoqI:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 ILE I 150
ALA I 226
ILE A  61
ASN I 260
TYR I 173
 None
 1.38A 4gh8B-4zoqI:
undetectable		 4gh8B-4zoqI:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 9 ARG I 319
ALA I 273
GLY I 277
VAL I 424
ILE I 321
 None
 0.97A 4ll3B-4zoqI:
undetectable		 4ll3B-4zoqI:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 7 GLN I 129
LEU I 388
THR I 135
THR I 202
 None
 1.12A 4mbsA-4zoqI:
undetectable		 4mbsA-4zoqI:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 4 LEU I 345
SER I 370
LEU I 377
LEU I 330
 None
 1.00A 4n09A-4zoqI:
5.2		 4n09A-4zoqI:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 5 LEU I 345
SER I 370
LEU I 377
LEU I 330
 None
 1.01A 4n09B-4zoqI:
5.5		 4n09B-4zoqI:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 5 LEU I 345
SER I 370
LEU I 377
LEU I 330
 None
 1.02A 4n09D-4zoqI:
4.9		 4n09D-4zoqI:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		3 / 3 GLU I 232
THR I 204
HIS I 231
 None
 0.84A 4q15A-4zoqI:
undetectable		 4q15A-4zoqI:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		3 / 3 GLU I 232
THR I 204
HIS I 231
 None
 0.87A 4q15B-4zoqI:
2.9		 4q15B-4zoqI:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		3 / 3 GLU I 232
THR I 204
HIS I 231
 None
 0.81A 4ydqB-4zoqI:
2.8		 4ydqB-4zoqI:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 11 GLU I 395
HIS I 142
VAL I 201
VAL I 145
LEU I 388
 None
 1.29A 4ygfD-4zoqI:
undetectable		 4ygfD-4zoqI:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 LEU I 123
LEU I 330
LEU I 377
GLY I 327
PHE I 125
 None
 0.96A 5j7wC-4zoqI:
undetectable		 5j7wC-4zoqI:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 7 GLY A  85
ALA A  86
ASP A  87
GLY A  62
 None
 0.69A 5kqyB-4zoqA:
undetectable		 5kqyB-4zoqA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		3 / 3 THR I 375
SER I 272
ASP I 151
 None
 0.73A 5kvaA-4zoqI:
undetectable		 5kvaA-4zoqI:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		3 / 3 GLY I 187
THR I 324
PRO I 380
 None
 0.60A 5v5zA-4zoqI:
undetectable		 5v5zA-4zoqI:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 ARG I 140
VAL I 431
LEU I 410
GLY I 384
ILE I 197
 None
 1.19A 5vooA-4zoqI:
undetectable		 5vooA-4zoqI:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		6 / 12 GLY I 153
GLY I 187
ASP I 182
SER I 180
VAL I 179
ILE I 150
 None
 1.17A 5wy0A-4zoqI:
undetectable		 5wy0A-4zoqI:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		4 / 8 ILE I 203
THR I 202
GLU I 139
SER I 391
 None
 1.12A 6c06C-4zoqI:
undetectable		 6c06C-4zoqI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 LEU I 123
LEU I 330
LEU I 377
GLY I 327
PHE I 125
 None
 0.95A 6qxsB-4zoqI:
undetectable		 6qxsB-4zoqI:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 LEU I 123
LEU I 330
LEU I 377
GLY I 327
PHE I 125
 None
 0.94A 6qyaB-4zoqI:
undetectable		 6qyaB-4zoqI:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 4zoq INTRACELLULAR SERINE
PROTEASE
(Bacillus
licheniformis) 		5 / 12 LEU I 123
LEU I 330
LEU I 377
GLY I 327
PHE I 125
 None
 0.95A 6qyaD-4zoqI:
undetectable		 6qyaD-4zoqI:
21.68