SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zoy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 6 VAL A 258
THR A 244
GLU A 260
LEU A 302
 None
 1.13A 1s8fB-4zoyA:
undetectable		 1s8fB-4zoyA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 5 LEU A 417
ARG A 414
ARG A 415
ILE A 392
 None
 1.49A 2cmlA-4zoyA:
7.5		 2cmlA-4zoyA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 5 LEU A 417
ARG A 414
ARG A 415
ILE A 392
 None
 1.41A 2cmlB-4zoyA:
6.9		 2cmlB-4zoyA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 5 LEU A 417
ARG A 414
ARG A 415
ILE A 392
 None
 1.37A 2cmlC-4zoyA:
7.7		 2cmlC-4zoyA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 5 LEU A 417
ARG A 414
ARG A 415
ILE A 392
 None
 1.42A 2cmlD-4zoyA:
8.2		 2cmlD-4zoyA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 5 VAL A 258
THR A 257
VAL A 216
GLY A 210
 None
 1.11A 2p2fA-4zoyA:
undetectable		 2p2fA-4zoyA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 4 VAL A 258
THR A 257
VAL A 216
GLY A 210
 None
 1.12A 2p2fB-4zoyA:
undetectable		 2p2fB-4zoyA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		3 / 3 GLU A 532
HIS A 537
HIS A 538
 None
 0.83A 3co4A-4zoyA:
undetectable		 3co4A-4zoyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 7 ILE A 142
PHE A 147
PHE A 180
GLY A 137
 None
 1.07A 3em0B-4zoyA:
undetectable		 3em0B-4zoyA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		3 / 3 CYH A 198
PRO A 150
ASP A 202
 None
 0.97A 3hlwB-4zoyA:
undetectable		 3hlwB-4zoyA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_2
(NEURAMINIDASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 5 LEU A 417
ARG A 414
ARG A 415
ILE A 392
 None
 1.49A 3ticD-4zoyA:
8.7		 3ticD-4zoyA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 12 TYR A  77
ILE A 102
ASN A  79
VAL A 520
PHE A 147
 None
 1.24A 4a97A-4zoyA:
undetectable
4a97B-4zoyA:
undetectable		 4a97A-4zoyA:
20.84
4a97B-4zoyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 5 HIS A  74
LEU A 221
LEU A 183
ASP A 222
 None
 1.34A 4aqlA-4zoyA:
undetectable		 4aqlA-4zoyA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 12 ALA A 420
SER A 401
VAL A 426
GLN A 512
PHE A 510
 None
 1.26A 4c49A-4zoyA:
undetectable		 4c49A-4zoyA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 11 ILE A 402
ALA A 420
GLY A 419
GLU A 423
GLY A 452
 None
 1.16A 4e47A-4zoyA:
undetectable		 4e47A-4zoyA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 11 ILE A 402
ALA A 420
GLY A 419
GLU A 423
GLY A 452
 None
 1.15A 4e47B-4zoyA:
undetectable		 4e47B-4zoyA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 12 LEU A 328
LEU A 254
ILE A 325
THR A 285
VAL A 305
 None
 1.20A 4f4dB-4zoyA:
undetectable		 4f4dB-4zoyA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 4zoy SQT1
(Chaetomium
thermophilum) 		3 / 3 ASP A 153
ARG A 151
ASP A 222
 None
 0.47A 4fp9C-4zoyA:
undetectable		 4fp9C-4zoyA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 4zoy SQT1
(Chaetomium
thermophilum) 		3 / 3 ASP A 153
ARG A 151
ASP A 222
 None
 0.52A 4fp9F-4zoyA:
undetectable		 4fp9F-4zoyA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 11 ASP A 293
ILE A 370
THR A 369
GLY A 368
VAL A 305
 None
 0.67A 4qgiA-4zoyA:
undetectable		 4qgiA-4zoyA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 12 LEU A 289
SER A 288
LEU A 371
GLY A 327
ALA A 367
 None
 1.22A 5iktB-4zoyA:
undetectable		 5iktB-4zoyA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 12 LEU A 445
GLY A 396
ALA A 395
SER A 383
LEU A 384
 None
 1.07A 5jvzA-4zoyA:
undetectable		 5jvzA-4zoyA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4zoy SQT1
(Chaetomium
thermophilum) 		5 / 12 LEU A 445
GLY A 396
ALA A 395
SER A 383
LEU A 384
 None
 1.08A 5jvzB-4zoyA:
undetectable		 5jvzB-4zoyA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 6 GLY A 210
SER A 259
THR A 257
VAL A 216
 None
 1.20A 5ysiA-4zoyA:
undetectable		 5ysiA-4zoyA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 7 PHE A 296
ILE A 370
LEU A 371
ALA A 312
 None
 0.73A 6b5vA-4zoyA:
undetectable
6b5vC-4zoyA:
undetectable		 6b5vA-4zoyA:
8.41
6b5vC-4zoyA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 7 PHE A 296
ILE A 370
LEU A 371
ALA A 312
 None
 0.73A 6b5vC-4zoyA:
undetectable
6b5vD-4zoyA:
undetectable		 6b5vC-4zoyA:
8.41
6b5vD-4zoyA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 7 ALA A 312
PHE A 296
ILE A 370
LEU A 371
 None
 0.72A 6b5vB-4zoyA:
undetectable
6b5vD-4zoyA:
undetectable		 6b5vB-4zoyA:
8.41
6b5vD-4zoyA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 4zoy SQT1
(Chaetomium
thermophilum) 		4 / 4 MET A 450
GLY A 506
HIS A 498
GLY A 449
 None
 1.48A 6fgdA-4zoyA:
undetectable		 6fgdA-4zoyA:
22.51