SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 11 LEU A 110
ALA A 178
VAL A 101
LEU A 141
ARG A 128
 None
 1.45A 1kt6A-4zpdA:
undetectable		 1kt6A-4zpdA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 ASN A 302
ASN A 303
ILE A 325
GLY A 207
 None
 0.95A 1oniA-4zpdA:
undetectable
1oniB-4zpdA:
undetectable		 1oniA-4zpdA:
15.58
1oniB-4zpdA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 ASN A 302
ASN A 303
ILE A 325
GLY A 207
 None
 0.95A 1oniD-4zpdA:
undetectable
1oniF-4zpdA:
undetectable		 1oniD-4zpdA:
15.58
1oniF-4zpdA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.11A 1p7lC-4zpdA:
undetectable		 1p7lC-4zpdA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.11A 1p7lD-4zpdA:
undetectable		 1p7lD-4zpdA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.12A 1rg9A-4zpdA:
undetectable		 1rg9A-4zpdA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.13A 1rg9B-4zpdA:
undetectable		 1rg9B-4zpdA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.11A 1rg9C-4zpdA:
undetectable		 1rg9C-4zpdA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.11A 1rg9D-4zpdA:
undetectable		 1rg9D-4zpdA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 7 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 1.00A 1rxcC-4zpdA:
undetectable		 1rxcC-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 7 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.97A 1rxcD-4zpdA:
undetectable		 1rxcD-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 7 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 1.08A 1rxcF-4zpdA:
undetectable		 1rxcF-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 7 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 1.03A 1rxcL-4zpdA:
undetectable		 1rxcL-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 9 PHE A 217
PHE A 379
VAL A 372
LEU A 229
PHE A 322
 None
 1.27A 1wrkA-4zpdA:
undetectable
1wrkB-4zpdA:
undetectable		 1wrkA-4zpdA:
13.48
1wrkB-4zpdA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.20A 2obvA-4zpdA:
undetectable		 2obvA-4zpdA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 ASN A 302
SER A 299
ALA A 326
ASP A 330
 None
 1.29A 3aruA-4zpdA:
undetectable		 3aruA-4zpdA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 LEU A 256
TYR A 258
PHE A 191
LEU A 194
 None
 0.87A 3i45A-4zpdA:
undetectable		 3i45A-4zpdA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.97A 3kvvA-4zpdA:
undetectable		 3kvvA-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.96A 3kvvB-4zpdA:
undetectable		 3kvvB-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.93A 3kvvC-4zpdA:
undetectable		 3kvvC-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.94A 3kvvD-4zpdA:
undetectable		 3kvvD-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.95A 3kvvE-4zpdA:
undetectable		 3kvvE-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.99A 3kvvF-4zpdA:
undetectable		 3kvvF-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 LEU A 375
PHE A 374
ILE A 325
ALA A 326
 None
 0.70A 3mdrA-4zpdA:
undetectable		 3mdrA-4zpdA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 TYR A 120
ILE A 130
SER A 179
SER A 180
 None
 1.36A 3pmzD-4zpdA:
undetectable		 3pmzD-4zpdA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 12 VAL A 313
ILE A 305
PHE A 322
ILE A 339
TYR A 335
 None
 1.26A 3q5pA-4zpdA:
undetectable		 3q5pA-4zpdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		6 / 9 ASP A 238
ASN A 298
TYR A 327
GLY A 328
ASP A 329
ASP A 330
 None
 0.62A 3sfuA-4zpdA:
31.3		 3sfuA-4zpdA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		7 / 9 ASP A 238
SER A 289
THR A 294
TYR A 327
GLY A 328
ASP A 329
ASP A 330
 None
 0.72A 3sfuA-4zpdA:
31.3		 3sfuA-4zpdA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		7 / 9 ASP A 238
ASN A 298
TYR A 327
GLY A 328
ASP A 329
ASP A 330
LEU A 375
 None
 0.61A 3sfuB-4zpdA:
31.4		 3sfuB-4zpdA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 11 ASP A 238
SER A 289
THR A 294
GLY A 328
ASP A 329
 None
 0.86A 3sfuC-4zpdA:
31.3		 3sfuC-4zpdA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		6 / 11 LYS A 159
ARG A 174
ASP A 238
ASN A 298
GLY A 328
ASP A 329
 None
 1.02A 3sfuC-4zpdA:
31.3		 3sfuC-4zpdA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		6 / 11 LYS A 159
ASP A 238
THR A 294
ASN A 298
GLY A 328
ASP A 329
 None
 0.91A 3sfuC-4zpdA:
31.3		 3sfuC-4zpdA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 9 ASN A  65
GLY A   1
GLY A 285
ASN A 271
GLY A  64
 None
 1.29A 3ztvA-4zpdA:
undetectable		 3ztvA-4zpdA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.99A 4e1vA-4zpdA:
undetectable		 4e1vA-4zpdA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 7 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.97A 4e1vB-4zpdA:
undetectable		 4e1vB-4zpdA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.96A 4e1vC-4zpdA:
undetectable		 4e1vC-4zpdA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.96A 4e1vD-4zpdA:
undetectable		 4e1vD-4zpdA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.99A 4e1vE-4zpdA:
undetectable		 4e1vE-4zpdA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 6 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 1.00A 4e1vF-4zpdA:
undetectable		 4e1vF-4zpdA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 GLY A 207
GLN A  84
ARG A 307
ILE A 325
 None
 0.98A 4e1vH-4zpdA:
undetectable		 4e1vH-4zpdA:
19.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 5 LYS A  96
LEU A  97
GLU A  98
LEU A 138
LYS A 142
 None
 0.67A 4k4yA-4zpdA:
57.5		 4k4yA-4zpdA:
99.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 4 LYS A  96
LEU A  97
GLU A  98
LEU A 138
 None
 0.62A 4k4yE-4zpdA:
57.6		 4k4yE-4zpdA:
99.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 5 LYS A  96
LEU A  97
GLU A  98
LEU A 138
LYS A 142
 None
 0.63A 4k4yI-4zpdA:
57.6		 4k4yI-4zpdA:
99.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		3 / 3 HIS A 199
GLY A 293
ILE A 296
 None
 0.28A 4k50A-4zpdA:
52.5		 4k50A-4zpdA:
57.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		3 / 3 HIS A 199
GLY A 293
ILE A 296
 None
 0.27A 4k50I-4zpdA:
26.9		 4k50I-4zpdA:
57.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 7 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.18A 4odjA-4zpdA:
undetectable		 4odjA-4zpdA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 12 LEU A 269
LEU A 253
MET A 300
ILE A 304
VAL A  78
 None
 1.17A 4ok1A-4zpdA:
undetectable		 4ok1A-4zpdA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 12 GLY A 192
ASN A 193
GLN A 189
SER A 184
SER A 179
 None
 1.25A 4pooB-4zpdA:
undetectable		 4pooB-4zpdA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.15A 5a1iA-4zpdA:
undetectable		 5a1iA-4zpdA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 7 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.15A 5a1iA-4zpdA:
undetectable		 5a1iA-4zpdA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 12 LEU A 107
GLY A 106
SER A  91
PHE A 191
TYR A 258
 None
 1.21A 5czyA-4zpdA:
undetectable		 5czyA-4zpdA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
GLY A 426
VAL A 392
HIS A 390
 None
 0.78A 5f8yA-4zpdA:
undetectable		 5f8yA-4zpdA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 PHE A 191
GLY A 192
THR A 263
TYR A 268
 None
 0.98A 5flcB-4zpdA:
undetectable		 5flcB-4zpdA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 PHE A 191
GLY A 192
THR A 263
TYR A 268
 None
 0.97A 5flcF-4zpdA:
3.0		 5flcF-4zpdA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.13A 5t8sB-4zpdA:
undetectable		 5t8sB-4zpdA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.21A 6fbnB-4zpdA:
undetectable		 6fbnB-4zpdA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.16A 6fboA-4zpdA:
undetectable		 6fboA-4zpdA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 8 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.14A 6fcdA-4zpdA:
undetectable		 6fcdA-4zpdA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		4 / 7 HIS A 424
PRO A 391
PHE A 462
ASP A 215
 None
 1.15A 6g6rA-4zpdA:
undetectable		 6g6rA-4zpdA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 4zpd RNA-DIRECTED RNA
POLYMERASE
(Enterovirus
B) 		5 / 12 ILE A 301
TYR A  81
ILE A  90
PHE A 191
MET A 187
 None
 1.42A 6j20A-4zpdA:
undetectable		 6j20A-4zpdA:
22.14