SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zpl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 4zpl PROTEIN PCDHB1
(Mus
musculus) 		3 / 3 ASP A  23
LEU A  24
HIS A  77
 None
 0.58A 1qknA-4zplA:
undetectable		 1qknA-4zplA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 4zpl PROTEIN PCDHB1
(Mus
musculus) 		4 / 8 ILE A 200
PHE A 150
LEU A 166
PHE A 124
 None
 0.85A 2vdbA-4zplA:
undetectable		 2vdbA-4zplA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 4zpl PROTEIN PCDHB1
(Mus
musculus) 		4 / 4 ASP A 131
ASP A 188
GLY A 196
THR A 143
 CA  A 415 (-2.5A)
CA  A 415 (-3.6A)
None
NAG  A 401 (-4.7A)
 1.38A 3tl9B-4zplA:
undetectable		 3tl9B-4zplA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 4zpl PROTEIN PCDHB1
(Mus
musculus) 		4 / 6 GLY A  54
VAL A  28
GLY A  35
GLU A  33
 None
 0.86A 4dxuA-4zplA:
undetectable		 4dxuA-4zplA:
23.26