SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zpm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		5 / 9 THR A 219
LEU A 310
VAL A 311
VAL A 275
VAL A 234
 None
 1.43A 2l8mA-4zpmA:
undetectable		 2l8mA-4zpmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		4 / 6 LEU A 254
VAL A 293
VAL A 234
VAL A 235
 None
 0.87A 2z97A-4zpmA:
undetectable		 2z97A-4zpmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		4 / 6 HIS A 126
GLU A 128
PHE A 106
GLN A 131
 None
 1.08A 3gclA-4zpmA:
undetectable		 3gclA-4zpmA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		5 / 12 ILE A 268
VAL A 234
ILE A 313
VAL A 311
VAL A 309
 None
 0.86A 3iw1A-4zpmA:
undetectable		 3iw1A-4zpmA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		4 / 7 ASP A  64
TYR A  47
GLN A  10
GLU A   8
 CA  A 804 (-3.2A)
None
None
CA  A 805 ( 3.0A)
 1.23A 3l2vA-4zpmA:
undetectable		 3l2vA-4zpmA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		4 / 7 ASP A  64
ASP A 101
ASN A 102
GLU A   8
 CA  A 804 (-3.2A)
CA  A 804 ( 2.8A)
CA  A 805 (-4.8A)
CA  A 805 ( 3.0A)
 1.12A 4feuB-4zpmA:
undetectable		 4feuB-4zpmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		4 / 8 LEU A 254
VAL A 293
VAL A 234
VAL A 235
 None
 0.82A 4l4bA-4zpmA:
undetectable		 4l4bA-4zpmA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		4 / 4 HIS A 181
ALA A 179
VAL A 205
GLU A 176
 None
None
None
CA  A 808 ( 2.4A)
 1.02A 4n6pA-4zpmA:
undetectable		 4n6pA-4zpmA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		5 / 12 SER A  44
ILE A  63
ASP A 101
ILE A  96
ARG A  62
 None
None
CA  A 804 ( 2.8A)
None
None
 1.30A 4uroD-4zpmA:
undetectable		 4uroD-4zpmA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4zpm PROTEIN PCDHAC2
(Mus
musculus) 		4 / 8 LEU A 254
VAL A 293
VAL A 234
VAL A 235
 None
 0.86A 6cp4A-4zpmA:
undetectable		 6cp4A-4zpmA:
22.12