SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zps'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 7 VAL A  16
GLY A  17
ILE A  77
VAL A  90
 None
 0.77A 1p2yA-4zpsA:
undetectable		 1p2yA-4zpsA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 6 TYR A 250
GLY A 246
THR A 249
GLU A 242
 None
CA  A 805 ( 4.8A)
None
None
 1.00A 3fpjA-4zpsA:
undetectable		 3fpjA-4zpsA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		5 / 10 ILE A   2
VAL A  90
ILE A  79
ILE A  19
SER A  20
 None
 1.43A 3kpbD-4zpsA:
undetectable		 3kpbD-4zpsA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 5 ASP A 130
VAL A 133
GLY A 134
ASP A 187
 None
None
None
CA  A 803 (-3.3A)
 1.48A 3w9tA-4zpsA:
undetectable		 3w9tA-4zpsA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 5 ASP A 130
VAL A 133
GLY A 134
ASP A 187
 None
None
None
CA  A 803 (-3.3A)
 1.47A 3w9tB-4zpsA:
undetectable		 3w9tB-4zpsA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 5 ASP A 130
VAL A 133
GLY A 134
ASP A 187
 None
None
None
CA  A 803 (-3.3A)
 1.48A 3w9tC-4zpsA:
undetectable		 3w9tC-4zpsA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 5 ASP A 130
VAL A 133
GLY A 134
ASP A 187
 None
None
None
CA  A 803 (-3.3A)
 1.47A 3w9tD-4zpsA:
undetectable		 3w9tD-4zpsA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 5 ASP A 130
VAL A 133
GLY A 134
ASP A 187
 None
None
None
CA  A 803 (-3.3A)
 1.48A 3w9tE-4zpsA:
undetectable		 3w9tE-4zpsA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 5 ASP A 130
VAL A 133
GLY A 134
ASP A 187
 None
None
None
CA  A 803 (-3.3A)
 1.48A 3w9tF-4zpsA:
undetectable		 3w9tF-4zpsA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 5 ASP A 130
VAL A 133
GLY A 134
ASP A 187
 None
None
None
CA  A 803 (-3.3A)
 1.46A 3w9tG-4zpsA:
undetectable		 3w9tG-4zpsA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 7 ASP A 208
GLU A 176
ASP A 205
GLU A 242
 CA  A 806 ( 2.8A)
None
CA  A 804 (-2.7A)
None
 1.20A 4fevB-4zpsA:
undetectable		 4fevB-4zpsA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 8 ASP A 208
GLU A 176
ASP A 205
GLU A 242
 CA  A 806 ( 2.8A)
None
CA  A 804 (-2.7A)
None
 1.19A 4gkhD-4zpsA:
undetectable		 4gkhD-4zpsA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		4 / 4 ASN A  78
LEU A  23
PHE A  46
TYR A   4
 None
 1.27A 4u14A-4zpsA:
undetectable		 4u14A-4zpsA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 4zps MCG133388, ISOFORM
CRA_M
(Mus
musculus) 		5 / 10 ALA A 121
ILE A 113
PRO A 119
LEU A 171
TYR A 123
 None
 1.01A 4xj7A-4zpsA:
undetectable
4xj7B-4zpsA:
undetectable		 4xj7A-4zpsA:
21.87
4xj7B-4zpsA:
21.87