SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4zpx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		6 / 10 LEU A 250
ALA A 294
VAL A 301
ILE A  66
GLY A  67
THR A 249
 None
 1.43A 1k6cA-4zpxA:
undetectable		 1k6cA-4zpxA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 5 LEU A 185
VAL A 286
CYH A 288
ALA A 261
 None
 1.08A 1mz9D-4zpxA:
undetectable		 1mz9D-4zpxA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 4 LEU A 185
VAL A 286
CYH A 288
ALA A 261
 None
 1.08A 1mz9E-4zpxA:
undetectable		 1mz9E-4zpxA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 5 ASP A  91
LEU A 184
ALA A 111
LEU A  89
 None
 1.05A 1nh8A-4zpxA:
undetectable		 1nh8A-4zpxA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 11 MET A 233
GLY A 232
GLN A 272
THR A 270
THR A 283
 None
 1.47A 1v54G-4zpxA:
undetectable
1v54N-4zpxA:
0.5
1v54O-4zpxA:
undetectable		 1v54G-4zpxA:
12.94
1v54N-4zpxA:
22.98
1v54O-4zpxA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		3 / 3 GLU A 284
THR A 283
LEU A 185
 None
 0.66A 1v8bC-4zpxA:
undetectable		 1v8bC-4zpxA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 ILE A  53
ALA A  56
ALA A  57
LEU A  84
VAL A  43
 None
 0.93A 1xiuB-4zpxA:
undetectable		 1xiuB-4zpxA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 ILE A  53
ALA A  56
ALA A  57
LEU A  84
VAL A  43
 None
 0.90A 1xlsA-4zpxA:
undetectable		 1xlsA-4zpxA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 ILE A  53
ALA A  56
ALA A  57
LEU A  84
VAL A  43
 None
 0.89A 1xlsB-4zpxA:
undetectable		 1xlsB-4zpxA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 ILE A  53
ALA A  56
ALA A  57
LEU A  84
VAL A  43
 None
 0.90A 1xlsC-4zpxA:
undetectable		 1xlsC-4zpxA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 ILE A  53
ALA A  56
ALA A  57
LEU A  84
VAL A  43
 None
 0.89A 1xlsD-4zpxA:
undetectable		 1xlsD-4zpxA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 11 MET A 233
GLY A 232
GLN A 272
THR A 270
THR A 283
 None
 1.46A 2dyrG-4zpxA:
undetectable
2dyrN-4zpxA:
0.5
2dyrO-4zpxA:
undetectable		 2dyrG-4zpxA:
12.94
2dyrN-4zpxA:
22.98
2dyrO-4zpxA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 11 MET A 233
GLY A 232
GLN A 272
THR A 270
THR A 283
 None
 1.47A 2eijG-4zpxA:
undetectable
2eijN-4zpxA:
1.0
2eijO-4zpxA:
undetectable		 2eijG-4zpxA:
12.94
2eijN-4zpxA:
22.98
2eijO-4zpxA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 11 MET A 233
GLY A 232
GLN A 272
THR A 270
THR A 283
 None
 1.48A 2eilG-4zpxA:
undetectable
2eilN-4zpxA:
0.6
2eilO-4zpxA:
undetectable		 2eilG-4zpxA:
12.94
2eilN-4zpxA:
22.98
2eilO-4zpxA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 ARG A 332
LEU A 381
ALA A 368
THR A 324
ARG A 333
 None
 1.19A 2v0mC-4zpxA:
undetectable		 2v0mC-4zpxA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 7 PHE A 267
LEU A 258
ALA A 261
PHE A 290
 None
 0.83A 2vcvG-4zpxA:
undetectable		 2vcvG-4zpxA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 GLY A 296
GLU A 246
ASP A 299
THR A  71
GLU A  68
 None
 0.97A 2vdvE-4zpxA:
undetectable		 2vdvE-4zpxA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 11 GLY A 296
GLU A 246
ASP A 299
THR A  71
GLU A  68
 None
 0.96A 2vdvF-4zpxA:
undetectable		 2vdvF-4zpxA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 7 LEU A 207
ILE A 244
ALA A  56
ILE A  53
 None
 0.82A 2xkwA-4zpxA:
undetectable		 2xkwA-4zpxA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		3 / 3 GLY A 232
GLY A 205
GLY A 209
 None
 0.38A 3bogC-4zpxA:
undetectable		 3bogC-4zpxA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		3 / 3 GLY A 232
GLY A 205
GLY A 209
 None
 0.41A 3bogD-4zpxA:
undetectable		 3bogD-4zpxA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 VAL A  50
ALA A  56
ALA A  57
LEU A  84
VAL A  43
 None
 0.95A 3fc6C-4zpxA:
undetectable		 3fc6C-4zpxA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		3 / 3 ILE A  66
VAL A 301
ARG A 309
 None
 0.71A 3p73A-4zpxA:
undetectable		 3p73A-4zpxA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 LEU A 208
ALA A 261
LEU A 258
ALA A 237
ILE A 244
 None
 0.90A 3ut5D-4zpxA:
undetectable		 3ut5D-4zpxA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 ILE A 234
LEU A 242
ILE A 197
ALA A 199
ILE A 269
 None
 1.02A 3vrmA-4zpxA:
undetectable		 3vrmA-4zpxA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 11 ASP A 404
ALA A 392
GLY A 389
VAL A 405
VAL A 343
 None
 1.35A 4c5lA-4zpxA:
undetectable		 4c5lA-4zpxA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 9 ASP A 404
ALA A 392
GLY A 389
VAL A 405
VAL A 343
 None
 1.26A 4c5lB-4zpxA:
undetectable		 4c5lB-4zpxA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 10 ASP A 404
ALA A 392
GLY A 389
VAL A 405
VAL A 343
 None
 1.25A 4c5nB-4zpxA:
undetectable		 4c5nB-4zpxA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 10 ASP A 404
ALA A 392
GLY A 389
VAL A 405
VAL A 343
 None
 1.35A 4c5nD-4zpxA:
2.1		 4c5nD-4zpxA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 LEU A 208
ALA A 261
LEU A 258
ALA A 237
ILE A 244
 None
 0.81A 4o2bD-4zpxA:
undetectable		 4o2bD-4zpxA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		3 / 3 PRO A  85
LEU A  84
HIS A  62
 None
 0.70A 4pevA-4zpxA:
undetectable		 4pevA-4zpxA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_B_377B401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 5 TYR A 399
GLU A  31
GLU A  32
PHE A  27
 None
 0.82A 4twdA-4zpxA:
undetectable
4twdB-4zpxA:
undetectable		 4twdA-4zpxA:
21.12
4twdB-4zpxA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 7 GLU A  31
GLU A  32
PHE A  27
TYR A 399
 None
 0.87A 4twdF-4zpxA:
undetectable
4twdJ-4zpxA:
undetectable		 4twdF-4zpxA:
21.12
4twdJ-4zpxA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 6 TYR A 399
GLU A  31
GLU A  32
PHE A  27
 None
 0.86A 4twdG-4zpxA:
undetectable
4twdH-4zpxA:
undetectable		 4twdG-4zpxA:
21.12
4twdH-4zpxA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 LEU A 208
ALA A 261
LEU A 258
ALA A 237
ILE A 244
 None
 0.85A 4x20B-4zpxA:
undetectable		 4x20B-4zpxA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 LEU A 208
ALA A 261
LEU A 258
ALA A 237
ILE A 244
 None
 0.83A 5eypB-4zpxA:
undetectable		 5eypB-4zpxA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 LEU A 208
ALA A 261
LEU A 258
ALA A 237
ILE A 244
 None
 0.87A 5nm5B-4zpxA:
undetectable		 5nm5B-4zpxA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 8 VAL A 357
ILE A  33
GLU A  26
LEU A  23
 None
 0.62A 5og9A-4zpxA:
undetectable		 5og9A-4zpxA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 LEU A 292
LEU A 242
MET A  80
ILE A 312
LEU A  65
 None
 1.03A 5toaA-4zpxA:
undetectable		 5toaA-4zpxA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		4 / 5 LEU A 292
LEU A 242
MET A  80
TYR A 317
 None
 1.41A 5uc3A-4zpxA:
undetectable		 5uc3A-4zpxA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		3 / 3 THR A 323
MET A 325
HIS A 373
 None
 0.86A 5uunA-4zpxA:
undetectable		 5uunA-4zpxA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 4zpx ATP-DEPENDENT
PROTEASE LON
(Thermococcus
onnurineus) 		5 / 12 LEU A 208
ALA A 261
LEU A 258
ALA A 237
ILE A 244
 None
 0.90A 5xiwB-4zpxA:
undetectable		 5xiwB-4zpxA:
14.04